50results about How to "Reduce morbidity and mortality" patented technology

Chimeric toxin receptor proteins having a toxin receptor associated with an immunoglobulin complex having least a portion of an immunoglobulin heavy chain and at least a portion of an immunoglobulin light chain are described. Such chimeric toxin receptor proteins have improved stability as compared to chimeric toxin receptor proteins lacking the light chain. Anthrax and botulinum chimeric toxin receptor proteins with increased stability are also described.

Pharmaceutical preparations comprising one or more agents that reduce the number of circulating platelets to low normal or below normal levels formulated in a delivery system are provided. The pharmaceutical preparations are useful in the prophylactic and therapeutic treatment of subjects for the purpose of inhibiting vaso-occlusive events, including embolism, by reducing the number of circulating platelets to low normal to below normal levels.

The present invention provides methods of treating a coronavirus infection, and methods of reducing viral load, or reducing the time to viral clearance, or reducing morbidity or mortality in the clinical outcomes, in patients suffering from a coronavirus infection. The present invention further provides methods of reducing the risk that an individual will develop a pathological coronavirus infection, that has clinical sequelae. The present invention further provides methods of reducing the risk that an individual will develop SARS. The present invention further provides methods of treating SARS. The methods generally involve administering a therapeutically effective amount of a Type I or Type III interferon receptor agonist and / or a Type II interferon receptor agonist for the treatment of a coronavirus infection.

The invention discloses a green feed capable of improving broiler meat quality and a preparation method thereof. The green feed is prepared from the following raw materials in parts by weight: 40-70 parts of peanut cake, 20-40 parts of corn flour, 10-15 parts of bean dregs, 10-15 parts of pine needle powder, 8-18 parts of konjak refined flour, 5-15 parts of osmanthus, 5-10 parts of sodium tripolyphosphate, 15-30 parts of modified montmorillonite, 5-15 parts of vitamin complex, 5-15 parts of microelement additive, 5-10 parts of garlicin, 2-8 parts of lysine, 2-5 parts of yeast nucleotide, 3-10 parts of microbial flora, 5-12 parts of glucose, 2-5 parts of cellulase, 10-20 parts of cyclodextrin and 5-15 parts of sodium alginate. The green feed has the advantages of reasonable formula, comprehensive nutrition and improved taste, is suitable for broilers to eat, enhances the disease resistance of the broilers, lowers the incidence mortality, has higher utilization ratio, and improves the broiler meat quality, so that the broiler meat quality is soft and delicious.

The invention relates to the treatment of subjects for the purpose inhibiting vaso-occlusive events, including thrombosis and embolism, by administering agents which reduce the number of circulating platelets to low or below normal levels. Methods and pharmaceutical preparations comprising such agents are provided.

The invention discloses a heart health quality early warning system and an early warning method thereof. The system comprises an analysis and calculation module used for calculating an individual heart health quality assessment value by applying a regression analysis method and a perspective and retrospective investigation and analysis method according to a pre-established heart health quality index data model, a search module used for searching out a health quality level corresponding to the individual heart health quality assessment value in a heart health quality classification standard and obtaining an individual heart health quality level, and an output and early warning module used for outputting the individual heart health quality level and performing early warning prompting. According to the heart health quality early warning system, the hearts of healthy and sub-healthy individuals and individuals with heart diseases can be analyzed and predicted, heart quality events can be discovered early and prevention measures can be proposed, so that the heart event risk is lowered.

Provided are prophylactic and therapeutic methods of treatment of subjects for the purpose of inhibiting vaso-occlusive events, including embolism, by administering agents, including anagrelide and anagrelide derivatives, which reduce the number of circulating platelets to low normal to below normal levels. Methods and pharmaceutical preparations comprising such agents are provided.

The invention provides a gastrointestinal tract non-invasive detection system based on wireless energy supply, and relates to the field of endoscopes. The gastrointestinal tract non-invasive detection system comprises a detection video capsule system, an extracorporeal wireless energy supply device and an extracorporeal image processing device. The detection video capsule system comprises a shell, an optical system, a double-circuit lighting system, a poor light video image sensor, a master control system, an image wireless sending device, a rectifying device and a wireless energy receiving three-dimensional coil, wherein the optical system, the double-circuit lighting system, the poor light video image sensor, the master control system, the image wireless sending device, the rectifying device and the wireless energy receiving three-dimensional coil are arranged in the shell. According to the system, the whole digestive tract can be accurately detected.

The invention discloses concentrated feed for piglets, belonging to the field of feed for piglets. A premix comprises lactose, glucose, calcium powder, choline chloride, 98.5% lysine, methionine, threonine, a flavouring agent, ethoxyquin, an acidifier, vitamins for suckling pigs, microelements for the suckling pigs, sesame oil cake, folium ginkgo powder, chestnut kernel powder, peanut kernel powder, sweet potato powder, sweet potato vine, sweet potato leaf powder, dried potato powder, polygonum aviculare, Asia plantain, millet, broomcorn and liquorice. The invention further provides a processing method of the concentrated feed. The processing method comprises the following steps: (1) preparing the premix; and (2) preparing the feed. The concentrated feed comprises multiple components and is rich in nutrients, meets the requirement of the growth of the piglets, is good in palatability to excite the growth potential, and facilitates the growth of the piglets; the immunity of the piglets can be improved, and the diarrhea rate and the morbidity death rate are reduced; the digestive absorption of the piglets to the feed is promoted, the daily gain of the piglets is increased, the feed conversion ratio of the feed is remarkably increased, the production cost is lowered, the cultivating benefit is increased, and the growth speed is ensured.

The invention discloses pearl cytoactive liquid, which consists of the following components in percentage by mass: 0.5 to 5 percent of sodium chloride, 0.5 to 5 percent of taurine, 0.1 to 3 percent of sulfanilic acid, 0.1 to 1 percent of chondroitin sulfate and 86 to 95 percent of purified water. The invention also discloses application of the pearl cytoactive liquid to pearl culture. By the pearl cytoactive liquid, the suffering probability and mortality of clams can be reduced, the average weight and average yield of the clams can be increased, and the situation of pearl death is reduced substantially, so the pearl cytoactive liquid has an economic significance for the pearl culture.

The invention discloses high-conversion-rate broiler feed using the synergistic effect of mulberry twigs and red dates. The feed is prepared from raw materials in parts by weight as follows: 20-30 parts of bone meal, 4-6 parts of a choline chloride preparation, 1-3 parts of phytase, 4-7 parts of baical skullcap roots, 4-5 parts of feed-grade zeolite powder, 120-150 parts of rice chaff, 4-6 parts of salt, 35-55 parts of black bean flour, 6-8 parts of nutgrass galingale rhizome powder, 90-130 parts of bran, 6-8 parts of red ginseng, 10-12 parts of conch powder, 20-24 parts of the mulberry twigs, 28-32 parts of the red dates and 10-14 parts of a feed additive. The broiler feed is rich in nutrients, added Chinese herbal medicines can interfere with breeding of harmful microorganisms, the incidence and the death and culling rate of broilers are greatly decreased, health growth of the broilers is guaranteed, meanwhile, the conversion rate of the feed is increased, and the higher economic benefit is brought.

The invention discloses a novel aquaculture method. The method is characterized by comprising the steps of control over water temperature of an aquaculture pond, control over water quality of the aquaculture pond and cultivation of symbiotic bacteria. Through control over the water quality of the aquaculture pond and cultivation of the symbiotic bacteria, the water temperature is kept constant inan optimum temperature range for fish growth. By optimizing the quality of water in the aquaculture pond, the water quality can always meet the most suitable water quality requirements for fish growth, rapid growth of fishes in the aquaculture pond is ensured, the disease rate and mortality of aquatic products are decreased, the growth rate is increased, energy is saved, the cost is reduced, circulating pollution is alleviated, the quality of aquatic meat is improved, and high-yield aquaculture of the aquatic products is achieved.

The invention provides a genetic engineering subunit oral bicombined inactivated vaccine, and in particular relates to a porcine epidemic diarrhea virus and porcine transmissible gastroenteritis virus genetic engineering subunit oral bicombined inactivated vaccine, which is prepared by using lactococcus lactis capable of carrying out recombinant expression on S protein of porcine epidemic diarrhea virus and SLN protein of porcine transmissible gastroenteritis virus, wherein an amino acid sequence of the S protein of the porcine epidemic diarrhea virus is SEQ ID No. 1, a nucleotide sequence of a coding gene of the S protein of the porcine epidemic diarrhea virus is SEQ ID No. 2, and the SLN protein is formed by connecting genes of A and D antigenic sites with a gene of an N321 antigenic site of the porcine transmissible gastroenteritis virus. The prepared inactivated vaccine can provide effective homologous attacking protection; after being used for immunization, the inactivated vaccine can generate stronger immunity; after a pig group is inoculated with the vaccine, the morbidity and mortality rates of the pig group are obviously reduced; the genetic engineering subunit oral bicombined inactivated vaccine can be used for effectively preventing the prevalence and spread of porcine epidemic diarrhea and porcine transmissible gastroenteritis and reducing the economic loss, caused by the diseases, of pig husbandry, thus having wide application prospect.

The present description relates to methods of administering effective amounts of an anti-arrhythmic agent, e.g., dantrolene, azumolene or a pharmaceutically acceptable salt thereof, for the acute treatment of cardiac arrhythmias, e.g., atrial fibrillation, premature ventricular contraction, ventricular tachycardia or ventricular fibrillation, and prevention of subsequent cardiac arrhythmias, wherein the methods effectuate a reduction in morbidity and mortality.

The invention discloses a method for lowering turbot pedigree fry ascites disease morbidity and mortality. The method comprises the steps of firstly optimizing a maturity promoting breeding condition for parent fish; secondly adopting a scientific fine fry breeding method to formulate a reasonable and effective artificial breeding mating scheme so as to avoid inbreeding depression and achieve optimum mating combination among pedigrees; thirdly, adopting an optimized breeding scheme to conduct pedigree fry breeding, wherein through the implementation of the scheme, not only is the fry breeding cycle shortened, but the fry with stronger physique and higher disease resistance is also obtained, and the morbidity rate of ascites disease in a fry period is effectively reduced; finally, conducting timely isolation of the pedigree fry which are attacked by ascites disease and reasonable adjustment of the breeding method, and implementing a strategy of 'improvement of both internal environment and external environment'. In this way, expanding of range of the state of illness is prevented, the adaption environment of the fry is also timely improved, the survival rate of the fry is increased, and the turbot pedigree fry ascites disease morbidity and mortality rate are thus effectively lowered.

The invention provides a vibrio harveyi ML01 strain with a deposit number of CGMCC No. 11720. The vibrio harveyi ML01 strain can be used for preparing highly protective inactivated vibrio harveyi vaccine for aquaculture. The strain and the vaccine prepared from the strain can effectively prevent and control vibrio harveyi disease in mariculture fish, reduce morbidity and mortality, reduce the useamount of antibiotics in aquaculture production, improve economic benefits and protect ecological environment.

The invention discloses a daily ration for young ostriches. The daily ration comprises, by weight parts, 20-35 parts of snap bean pulp, 20-35 parts of rapeseed meal, 10-15 parts of wheat bran, 10-15 parts of cooked egg yolk, 5-10 parts of urena lobata, 1-5 parts of ardisia japonica and 1-5 parts of bidens pilosa. According to diet characteristics of the young ostriches, reasonable basic daily ration ingredients are configured, multiple characteristic traditional Chinese medicines are introduced, nutritional ingredients and medicinal characteristics of herbal medicines are fully utilized, the morbidity rate and the death rate are reduced, better conditions are created for growth of the young ostriches, and the daily ration is more suitable for artificial breeding of the ostriches.

The invention belongs to the technical field of animal nutrition and in particular relates to an anti-cold-stress nutritional preparation for quails. The preparation is prepared from the following raw materials by weight parts: 60-75 parts of hydrolyzed wheat protein, 15-30 parts of chickpea protein peptide, 0.8-1.0 part of vitamin C, 0.1-0.2 part of a sodium selenite premix containing 1wt% of selenium, 0.8-1.1 parts of a flow agent, 4-6 parts of maltodextrin and 2-4 parts of corn starch. The preparation has an important effect on solving current situations of poor cold resistance of the quails and low house temperature in winter during production of the quails, the physiological status of the quails in a stressful situation can be improved, the disease resistance of the quails is improved, the nutrient absorption speed of the quails is increased, the protein synthesis is promoted, the production performance of the quails is improved, and the feed utilization rate is increased.

Time-varying hyperglycemic stresses are derived from actual ICU patients and applied to non-critically ill virtual patients, using any model of normal glucose-insulin physiology that fulfills certain requirements, in order to model and simulate stress hyperglycemia. Other aspects provide: 1) a methodology to perform sensitivity analyses of the parameters of ICU insulin infusion therapy protocols and to improve the protocols; and 2) a training system for clinicians about the course and management of stress hyperglycemia in the ICU or other facility.

The present invention provides one kind of green environment protecting health feed produced with farm and sideline products, which wear rejected before, as main amterial and adding proper amount of Chinese herbal medicines or inorganic salt and chemical. Using the said side products can utilize the resource reasonably and avoid environmental pollution.

The invention discloses a method for feeding free-range chickens with lemon enzymes, and the free-range chickens are prepared from the following raw materials: corn, soybean meal, wheat bran, premix, fish meal, lemon enzymes, calcium hydrogen phosphate, licorice roots, table salt and multivitamins. Acid-base balance is an adjusting function of maintaining the acidity of body fluid of a chicken body to fluctuate within a very small range so as to meet the requirements of normal physiological activities and metabolism, and lemon enzyme food is very low in calorie, is rich in citric acid and is a first-class source of potassium, calcium, iron, vitamin C and bioflavonoids. The bioflavonoids are substantially lower than the fruit because they are predominantly present in the peel and membrane of the fruit. The lemon enzyme contains considerable citral, vitamin C and vitamin P, the green lemons contain an ingredient similar to insulin, and nutrition needed in the growth process of the chickens is guaranteed by adding the lemon enzyme, probiotics, nutrient sand, insect protein and various vitamins.

The invention provides a suckling pig food calling starter formula feed. The formula feed comprises, by mass, 20-30 parts of a base material, 50-60 parts of a main material, 10-15 parts of an auxiliary material, and 3-10 parts of an additive. The base material includes pea seedlings, fresh forage grass and sweet wormwood herb, the main material includes soybean meal, peas, corn, wheat bran, fish meal, bacillus freeze-dried powder, bifidobacterium freeze-dried powder, and lactic acid bacteria freeze-dried powder, and the auxiliary material includes ginseng, Codonopsis pilosula, radix stephaniaetetrandrae, radix aristolochiae, astragalus, ganoderma lucidum, honeysuckle, Chinese angelica, rhizoma polygonati, coix seed, radix asparagi, glossy privet fruit, Chinese wolfberry, jujube, ganodermalucidum, cassia twig, and radix bupleuri. The formula feed provided by the invention is added with Chinese herbal chelate and biological polypeptide, and improves the resistance ability of animals tohigh fever mixed infection, thus lowering the morbidity and mortality of animal groups. Because of the adding of fructo-oligosaccharide, polyfructose and L-carnitine, the feed can more effectively promote the proliferation of intestinal beneficial microflora, maintain intestinal health, and improve digestion and absorption functions.

The invention discloses a breeding method for prolonging mating Andrias breeding age and an apparatus, and the method comprises the steps of using a specific culture pond; forming a specific flow stimulation by increasing pool water volume of the mating Andrias gradually from early and mid march until the spawning induction breeding of the mating Andrias ends each year; and controlling the sexual gland growth, the resting and the body weight of the mating Andrias by seasonal bait feeding so as to prolong the breeding age of the mating Andrias. According to the method, the breeding age of the mating Andrias can be prolonged from 5-7 years to 7-10 years; the artificial breeding effect of the mating Andrias can be improved; the disease and mortality rate of the mating Andrias can be reduced; and the utilization value of the mating Andrias can be greatly improved.

The invention provides a traditional Chinese medicine preparation for treating hypertension, and relates to the technical field of traditional Chinese medicines. The preparation is prepared from the following medicinal raw materials in parts by weight: 1-10 parts of pseudo-ginseng, 5-10 parts of polygonum multiflorum, 1-4 parts of polygonatum kingianum, 6-10 parts of black sesame, 1-10 parts of saposhnicovia divaricata, 1-10 parts of uncaria rhynchophylla, 5-15 parts of selfheal, 1-15 parts of mulberry leaf, 1-15 parts of chrysanthemum, 1-15 parts of spanishneedles herb, 1-15 parts of radix zanthoxyli and 1-15 parts of apocynum venetum. The traditional Chinese medicine preparation is capable of treating hypertension diseases, furthest reducing cardiocerebral event occurrence rate and death rate and prolonging patient lives, and has the advantages of excellent drug property, good safety, no pollution and no side effect and is purely nature.

The invention discloses a Chinese herbal medicine preparation for preventing common diseases of pond culture haliotis discus hannai. The Chinese herbal medicine preparation is prepared from, by weight parts, 16-20 parts of scutellaria baicalensis, 16-20 parts of gardenia, 12-18 parts of sophora flavescens, 8-12 parts of andrographis paniculata, 12-18 parts of gardenia jasminoides, 12-18 parts of polygonum cuspidatum, 2-6 parts of achyranthes bidentata, 8-11 parts of dandelion, 2-6 parts of gallnut and 8-20 parts of radix glycyrrhizae. By utilizing reasonable matching of conventional Chinese herbal medicines, the common disease problem of pond culture haliotis discus hannai can be prevented through sterilization, and by adoption of the Chinese herbal medicine preparation, it can be guaranteed that no toxic or harmful chemical agent remains in pond water and haliotis discus hannai. By use of the Chinese herbal medicine preparation, the common diseases of pond culture haliotis discus hannai can be effectively prevented, the survival rate and the spawning rate of pond culture haliotis discus hannai are improved, and the Chinese herbal medicine preparation is of great significance for breeding pond culture haliotis discus hannai.

The invention relates to a traditional Chinese medicine composition. The traditional Chinese medicine composition comprises 200 to 2000 parts of euphorbiae humifusae herb, 10 to 200 parts of catechu,10 to 100 parts of dark plum, 10 to 200 parts of scorched hawthorn fruit, 20 to 400 parts of Poria cocos, 10 to 200 parts of white peony roots and 10 to 100 parts of licorice roots. The invention alsorelates to a preparation method for the traditional Chinese medicine composition. The invention further relates to a traditional Chinese medicine preparation and application of the same as a drug fortreating pathogenic diarrhea, nonpathogenic diarrhea, damp-heat type diarrhea or spleen-deficiency type diarrhea caused by swine viruses and bacteria.

A method of treating a patient who has extravasation of blood from an intravascular compartment to an extravascular compartment. An agent is administered to the patient which mitigates a harmful effect of break-down products of blood at an extravascular site, resulting in the patient having reduced morbidity and mortality. The morbidity and mortality of the patient is further reduced by concomitant administration of a suspension of submicron protein spheres having a molecular weight of ranging from 780 billion Daltons to less than 0.8 billion Daltons.

The invention relates to the technical field of livestock and poultry breeding, in particular to an anti-stress Chinese herbal medicine feed additive for muscovy ducks and a preparation method and application of the anti-stress Chinese herbal medicine feed additive. The invention aims to solve the problems that when the Muscovy ducks are in stress reaction, the health of the Muscovy ducks is harmed, and the meat quality of the Muscovy ducks is reduced. The anti-stress Chinese herbal medicine feed additive comprises a solid type and a liquid type, wherein the solid type anti-stress Chinese herbal medicine feed additive is formed by mixing an anti-stress feed additive A and an anti-stress additive B according to the mass fraction of 50: 50; the liquid anti-stress Chinese herbal medicine feed additive is formed by fermenting and filtering organic selenium earthworm liquid, selenium-rich feed mulberry leaves and orange fruits. When the Muscovy ducks are subjected to stress such as long-distance transportation, cold and heat stress, environmental climate change and the like, 1.5%-3.5% of the solid anti-stress Chinese herbal medicine feed additive is added into the feed, and 1%-3% of the liquid anti-stress Chinese herbal medicine feed additive is added into drinking water, so that the stress response of the Muscovy ducks can be effectively relieved, the feed conversion rate is improved, and the morbidity and mortality are reduced.