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Novel anti-acne composition and application thereof in cosmetics

A composition and cosmetic technology, applied in the directions of cosmetics, cosmetic preparations, drug combinations, etc., can solve problems such as beneficial and harmful skin, and achieve the effect of maintaining a healthy state and having a significant anti-acne effect.

Inactive Publication Date: 2020-03-24
GUANGZHOU KENENG COSMETICS RES CO LTD +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are different genotypes of P. acnes, some beneficial to the skin and some harmful

Method used

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  • Novel anti-acne composition and application thereof in cosmetics
  • Novel anti-acne composition and application thereof in cosmetics

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] The formula and preparation method of embodiment 1 antiacne composition

[0033] The formula of table 1 anti-acne composition

[0034]

[0035] Preparation method: Stir the pine leaf extract, lactobacillus fermentation product, butanediol, dipropylene glycol and deionized water evenly at room temperature.

Embodiment 2

[0036] Example 2 Cytotoxicity Test

[0037] The cytotoxicity test was carried out according to the national standard GB / T 16886.5-2003 / ISO 10993-5:1999 of the People's Republic of China. Tested using a biological model of human epidermal keratinocytes.

[0038] The test samples include compositions 1, 3-4 and comparative compositions 1-3.

[0039] Table 2 Cytotoxicity test results

[0040] combination Cytotoxicity Test Results Comparative Composition 1 non-cytotoxic Comparative Composition 2 non-cytotoxic Composition 1 non-cytotoxic Composition 3 non-cytotoxic Composition 4 non-cytotoxic Comparative composition 3 mild cytotoxicity

[0041] The results show that comparative composition 3 has cytotoxicity, which proves that when the contents of the pine leaf extract and the fermentation product of Lactobacillus are higher than 15%, the cytotoxicity is exhibited.

Embodiment 3

[0042] Embodiment 3 acne essence

[0043] Compositions 1, 3, 4 and comparative composition 1-2 in Example 1 are used to prepare acne essence 1-5 (table 3) respectively

[0044] Table 3 The formula of anti-acne essence

[0045]

[0046] The preparation method of the above-mentioned acne essence is as follows:

[0047] 1. Add phase A into the emulsification pot in turn, stir and heat to 80-85°C, stir evenly until phase A is completely dissolved, homogenize for 3 minutes, and sterilize at constant temperature for 10 minutes.

[0048] 2. Vacuumize, turn on the cooling water to cool down, adjust the stirring speed to 800r / min, add phase B at 60°C, stir evenly, and homogenize for 1 minute.

[0049] 3. When the temperature drops to 42°C, add Phase C and Phase D and stir evenly.

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PUM

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Abstract

The invention belongs to a composition in the technical field of cosmetic compositions, and particularly relates to a novel anti-acne composition and application thereof in cosmetics. The anti-acne composition disclosed by the invention comprises the following components: a pinus koraiensis leaf extract and a lactobacillus fermentation product. The anti-acne composition of the present invention isbased on quorum effect and has the advantage that treatment is performed while maintaining microflora balance. The novel anti-acne composition is safe to use, is nontoxic, and is remarkable in anti-acne effect.

Description

technical field [0001] The invention belongs to the technical field of cosmetic compositions, and in particular relates to a novel anti-acne composition and its application in cosmetics. Background technique [0002] Propionibacterium bacteria get their name from their ability to produce propionic acid, but they actually live symbiotically on the skin of most healthy adults. In atopic dermatitis and psoriasis, the number of P. acnes decreases in the diseased state and increases after treatment. The protective role of the symbiotic state is largely unexplored and poorly understood. The skin microbiomes of older healthy individuals were similar to those of younger healthy individuals, both containing high levels of the bacterium P. acnes, which plays a role in maintaining healthy skin. There are different genotypes of P. acnes, some beneficial to the skin and some harmful. [0003] P. acnes is the only bacterium that can metabolize our sebum because it secretes lipase, whic...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/34A61K8/9767A61K8/99A61P17/10A61Q19/00
CPCA61K8/345A61K8/99A61K2800/5922A61K2800/85A61Q19/00A61K8/9767A61P17/10
Inventor 林娜妹张慧李传茂张伟杰张楚标
Owner GUANGZHOU KENENG COSMETICS RES CO LTD
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