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Microfluidic disc and method for determining thyroid function based on washing-free microfluidic technology

A microfluidic, disc technology, applied in chemical instruments and methods, measuring devices, biological testing, etc., can solve problems such as low testing efficiency, and achieve the effects of improving accuracy, improving testing efficiency, and reducing quantity

Inactive Publication Date: 2020-04-17
北京柏兆嘉业科技有限公司
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  • Application Information

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Problems solved by technology

At present, the determination of the seven thyroid function indicators requires multiple sampling and multiple drops, and the test efficiency is low

Method used

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  • Microfluidic disc and method for determining thyroid function based on washing-free microfluidic technology
  • Microfluidic disc and method for determining thyroid function based on washing-free microfluidic technology

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Embodiment Construction

[0023] The following is attached figure 1 , to further illustrate a specific implementation of a microfluidic disc of the present invention. A microfluidic disc of the present invention is not limited to the description of the following examples.

[0024] Such as figure 1 As shown, a microfluidic disc 12 includes a sample inlet 1 , a plurality of detection units, a redundant sample channel 4 , a pressure balance valve 5 and a waste liquid tank 11 . Wherein, the structures of the detection units can be the same, and each detection unit includes a sampling tank 3 , a surface tension valve 6 , a preloaded reagent tank 7 , a reaction flow channel 8 , a measurement pool 9 and a waste liquid flow channel 10 .

[0025] The sample inlet 1 is located in the middle of a certain radius of the microfluidic disc 12 , and is connected to the front inlet of the sample channel 3 through the sample channel 2 . The sample flows from the sample inlet 1 into the sample dividing channel 2, and ...

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Abstract

The invention discloses a microfluidic disc and a method for determining thyroid function based on washing-free microfluidic technology. The micro-fluidic disc is provided with a sample inlet, a wasteliquid tank and a plurality of detection units; wherein each detection unit comprises a sample separation tank, a reagent pre-loading tank and a measuring tank, and the sample separation tank, the pre-loading reagent tank and the measuring tank are sequentially communicated, the sample separation tank is connected with the sample inlet, different pre-loaded reagents are packaged in the pre-loading reagent tanks, the measuring tank is communicated with the waste liquid tank, and a surface tension valve is arranged in a connecting channel between an outlet of the sample separation tank and thepre-loading reagent tank. The microfluidic disc disclosed in the invention comprises a plurality of the detection units, each detection unit comprises a pre-loading reagent tank, so that packaging ofdifferent pre-loading reagents in a plurality of pre-loading reagent tank is realized based on requirements, detection of seven thyroid function indexes can be achieved on the same microfluidic disc,it can be guaranteed that the sample adding amount, the reaction mode and the reaction time are completely unified, and the accuracy of the detection effect is improved.

Description

technical field [0001] The invention belongs to the technical field of in vitro diagnosis of immunity, and in particular relates to a microfluidic disk and a method for measuring thyroid function based on the wash-free microfluidic technology. Background technique [0002] Microfluidic technology uses the physical and chemical properties and scale effects of multiphase microfluidics to perform the generation, manipulation, reaction, analysis and screening of multiphase microfunctional units of microdroplets in microchannels, and is widely used in immunoassays and molecular diagnostics. . The determination of the seven thyroid function indexes is for thyroxine (T4), triiodothyronine (T3), thyroid stimulating hormone (TSH), free T3, free T4, antithyroglobulin antibody (TG antibody) and antithyroid Determination of peroxidase antibody (TPO antibody). At present, the determination of the seven thyroid function indicators requires multiple sampling and multiple drops, and the t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B01L3/00G01N33/68G01N33/78
CPCB01L3/5027G01N33/6854G01N33/78
Inventor 姚洪涛高希曾
Owner 北京柏兆嘉业科技有限公司
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