Manufacturing method of microgel stent based on flexible mold capillary folding technology
A flexible mold and manufacturing method technology, applied in biochemical equipment and methods, cell culture supports/coatings, microorganisms, etc., can solve the problems of difficult to form three-dimensional microgel scaffolds, difficult to control scaffold morphology and other problems
Active Publication Date: 2020-04-24
XI AN JIAOTONG UNIV
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AI-Extracted Technical Summary
Problems solved by technology
A manufacturing method of a microgel stent based on a flexible mold capillary folding technology comprises the following steps: firstly, a flexible mold is designed, then the flexible mold is prepared, a microgel stent is prepared, and a grabbing structure of the flexible mold is in contact with the liquid level of hydrogel so that the hydrogel will wet the surface of the grabbing structure and capillary force is automatically generated at a contact line position; subsequently, the flexible mold is gradually pulled away from the liquid level of the hydrogel, the grabbing structure is graduallybent and deformed until the grabbing structure is finally closed under the action of capillary force, the hydrogel is wrapped in a formed cavity, and then the hydrogel is cross-linked and cured; andfinally, demolding of the microgel stent is conducted, the flexible mold and the hydrogel are immersed in water, water molecules infiltrate the interface of the grabbing structure and the hydrogel anddestroy the binding force between the grabbing structure and the hydrogel, the grabbing structure is automatically opened, and the hydrogel automatically falls off. According to the invention, controllable manufacturing of micron-scale hydrogel stents with different morphologies can be realized.
Cell culture supports/coatingProsthesis
Biomedical engineeringNanotechnology +2
- Experimental program(1)
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