Self-driven micro-fluidic chip
A microfluidic chip, self-driving technology, applied in laboratory utensils, laboratory containers, chemical instruments and methods, etc., can solve the problems of short reaction time of reaction reagents, reduce the measurement accuracy of the sample to be tested by the chip, etc. The effect of increasing the detection range, increasing the surface area, and increasing the response time
Inactive Publication Date: 2020-04-28
重庆创芯生物科技有限公司
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Problems solved by technology
[0005] The purpose of the invention of the present invention is: in the prior art, when the sample to be tested passes through the inside of the chip, the flow velocity of the sample to be tested is too fast, so that the reaction time between the sample to be tested and the reaction reagent embedded in the chip is relatively short, causing the sample to be tested to It cannot fully react with the reaction reagent, which reduces the problem of the measurement accuracy of the chip to be tested, and provides a self-driven microfluidic chip
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Embodiment 1
[0030] Such as figure 1 and figure 2 As shown, a self-driven microfluidic chip includes a base plate 1 and a cover plate 2, the base plate 1 and the cover plate 2 form a chip with a channel 4 through a connecting plate 3, and the cover plate 2 is provided with a channel hole 21, the channel 4 is provided with a blood filtration tank 41, a reaction chamber 42, a time-controlled valve 42, a detection area 44 and a waste liquid pool 45 that are sequentially communicated with the through hole 21, the reaction chamber 42 and the The detection area 44 is provided with a microcolumn 5, and the microcolumn 5 is arranged on the bottom plate 1, and the microcolumn 5 includes a body 51 and an arc-shaped protrusion 52 arranged at the end of the body 51, figure 1 The middle direction A is the flow direction of the sample to be tested in the channel 4, and the base plate 1, the cover plate 2 and the connection plate 3 are bonded to form the chip.
[0031] Such as figure 1 As shown, the ...
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Abstract
The invention relates to the technical field of micro-fluidic chips, in particular to a self-driven microfluidic chip. The microfluidic chip includes a bottom plate and cover plate, wherein the bottomplate and the cover plate form a chip with a channel through a connecting plate; a through hole is formed in the cover plate; a blood filtering groove, a reaction chamber, a time control valve, a detection area and a waste liquid pool which are sequentially communicated with the through hole are arranged in the channel; both the reaction chamber and the detection area are provided with micro-columns; the micro-columns are arranged on the bottom plate; each micro-column comprises a body and an arc-shaped protrusion arranged at the end of the body. An arc-shaped bulge structure is additionallyarranged on a body of a micro-column of an existing reaction chamber and a detection area, so that the apparent contact angle of the upper part of the micro-column is reduced, and the wettability of the upper part of the micro-column is improved, the flowing speed of a to-be-detected sample is low when the to-be-detected sample flows through the reaction chamber and the detection area, the to-be-detected sample can fully react with a reaction reagent, and the subsequent measurement precision of the to-be-detected sample is improved.
Description
technical field [0001] The invention relates to the technical field of microfluidic chips, in particular to a self-driven microfluidic chip. Background technique [0002] The microfluidic chip integrates the basic operation units such as sample preparation, reaction, separation, and detection in the biological, chemical, and medical analysis processes into a micron-scale chip, and automatically completes the entire analysis process. Due to its great potential in the fields of biology, chemistry, and medicine, it has developed into a new research field interdisciplinary in biology, chemistry, medicine, fluid, electronics, materials, and machinery. [0003] Microfluidic chip POCT detection technology is a rapid detection technology developed in the past ten years. Because microfluidic technology has the characteristics of sample flow control, closed chip, small pipeline, and strong controllability, the detection sensitivity and detection repeatability of microfluidic chip POC...
Claims
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IPC IPC(8): B01L3/00
CPCB01L3/5027
Inventor 钟越赵朝辉于梦露兰诗玉杨杰
Owner 重庆创芯生物科技有限公司