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Preoperative enteral nutritional composition

A technology of enteral nutrition and composition, applied in the fields of drug combination, food science, application, etc., can solve the problems of accelerating tissue repair and wound healing, the incidence of adverse complications, and reducing insulin resistance.

Inactive Publication Date: 2020-05-19
江苏西宏生物医药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, preoperative fasting and drinking may bring the following problems: (1) cause a series of adverse symptoms before operation; (2) affect tissue repair and wound healing; (3) long-term fasting puts patients under metabolic stress state, can cause insulin resistance, which is not conducive to reducing the incidence of postoperative complications
[0009] However, there are few studies on drinks suitable for preoperative drinking. It is necessary to develop a preoperative drink suitable for patients to better reduce the series of adverse symptoms before surgery; accelerate tissue repair and wound healing; better reduce surgical treatment Respond to the stress caused by the patient, better reduce insulin resistance, and better reduce the incidence of postoperative complications

Method used

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  • Preoperative enteral nutritional composition
  • Preoperative enteral nutritional composition
  • Preoperative enteral nutritional composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1-1

[0103] Recipe: Human milk oligosaccharides: 0.5g of LNnT, 4g of maltodextrin, 8g of fructose, add ion-free purified water to 100ml (or g), and mix the above components.

Embodiment 1

[0105] The LNnT in the formula of Example 1 was replaced by a mixture of equal amounts of maltodextrin and fructose (weight ratio 1:2), and the others remained unchanged.

Embodiment 2-1

[0111] Recipe: Human milk oligosaccharide: 2.5g of 2’-FL, 4g of maltodextrin, 8g of fructose, add ion-free purified water to 100ml (or g), mix the above components and get ready.

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Abstract

The present invention provides a preoperative enteral nutritional composition for reducing the stress response of surgical treatment to a patient. The composition comprises human milk oligosaccharide(HMO), maltodextrin and fructose. The composition can accelerate tissue repair and wound healing, reduce insulin resistance, reduce postoperative complication occurrence rate and mortality, acceleratepatient rehabilitation, shorten hospitalization days and improve patient prognosis.

Description

【Technical field】 [0001] The invention relates to an enteral nutrition solution. More specifically, the present invention relates to a preoperative enteral nutrition solution based on a composition of human milk oligosaccharides (HMO), maltodextrin and fructose. [0002] 【technical background】 [0003] It is recommended to perform surgery on an empty stomach when performing general surgery. At this time, it will cause a large amount of lack of nutrition in the body, so that it will cause coma, hypoglycemia, hypotension or other diseases. [0004] In order to reduce the volume and acidity of gastric contents and prevent vomiting and aspiration during anesthesia, it is generally stipulated that adult surgical patients should fast for 8-12 hours and drink for 4 hours before operation. However, preoperative fasting and drinking may bring the following problems: (1) cause a series of adverse symptoms before operation; (2) affect tissue repair and wound healing; (3) long-term fast...

Claims

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Application Information

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IPC IPC(8): A23L33/125A23L33/00A61K31/702A61K31/7004A61K31/715A61P3/02
CPCA23L33/125A23L33/40A61K31/702A61K31/7004A61K31/715A61P3/02A23V2002/00A61K2300/00A23V2200/30A23V2250/5114A23V2250/51A23V2250/606
Inventor 张新明徐增松王志强
Owner 江苏西宏生物医药有限公司
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