Biological microscopic cutting device based on flexible vibration reduction ultrasonic amplitude transformer

Abstract

The invention discloses a biological microscopic cutting device based on a flexible vibration reduction ultrasonic amplitude transformer. The biological microscopic cutting device comprises an energyconverter, the amplitude transformer, a connecting ring, a flexible mechanism and a cutting needle, wherein one shaft end of the amplitude transformer is connected with the energy converter, the othershaft end of the amplitude transformer penetrates through the connecting ring to be connected with the flexible mechanism, the amplitude transformer and the flexible mechanism are both connected withthe connecting ring, and the cutting needle is connected with the flexible mechanism. According to the biological microscopic cutting device based on the flexible vibration reduction ultrasonic amplitude transformer, the whole device works under the longitudinal vibration frequency, so that needle point disturbance caused by other vibration modes is avoided, needle point vibration is stabler, andthe cutting precision is improved; by means of the mode by which the flexible mechanism is combined with the amplitude transformer, transverse vibration can be restrained within a smaller range, meanwhile, axial vibration can be amplified, and the cutting precision and performance are improved; and each group of flexible parts in the flexible mechanism are arranged in a circumferential array modeby adopting four flexible hinges, so that the stress is more uniformly distributed in four directions, and the inhibition effect on the transverse vibration is further improved.

Description

technical field [0001] The invention relates to the technical field of biomedicine, in particular to a biological microcutting device based on a flexible vibration-absorbing ultrasonic horn. Background technique [0002] With the rapid development of modern biomedicine, biological piezoelectric ultrasonic cutting technology has been more and more widely used, and the objects of biological tissue cutting have gradually evolved from bone tissue in clinical medicine and lesion soft tissue in surgery to more microscopic Tumor tissue slices, single cells, etc., which put forward high requirements for tools for cutting biological tissues. In the process of microdissection of microscopic biological tissues, the focus and difficulty are mainly on how to precisely separate the target tissue while reducing the damage to the tissue. Some scholars have proposed a micro-cutting method of ultrasonic vibration, which uses piezoelectric ceramics to drive the cutting needle to perform high-...

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Problems solved by technology

[0003] Nagoya University in Japan was the first to study the mechanism of microdissection based on ultrasonic vibration, and proposed a Z-direction vibration microdissection device, as shown in Figure 1(a), which consists of piezoelectric ceramics and a bent cutting needle. It is composed of piezoelectric ceramics that generate Z-direction high-frequency vibrations, and transmits the vibration energy to the needle tip through a mechanical connection, so as to achieve the purpose of tissue cutting. The cutting area is precisely positioned, and the insertion depth of the needle tip is also difficult to determine. It is easy to cause damage to the needle tip during the cutting process, so automatic cutting cannot be realized

Harbin Institute of Technology and Soochow University also proposed a microdissection device with piezoelectric ceramics in front, as shown in Figure 1(b), which directly connects piezoelectric ceramics to cutting needles, effectively reducing the energy transfer process. However, piezoelectric ceramics will inevitably be accompanied by a certain amount of lateral vibration when generating axial vibration for cutting. This lateral vibration is amplified through the transmission of the cutting needle. In the cutting of microstructure, Lateral vibration should be avoided as much as possible. Excessive lateral vibration will reduce the cutting accuracy and separation effect, and will cause cell damage or even death during the cutting process of living cells.

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