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A Double Negative Acoustic Metamaterial Based on Mie Resonance for Transcranial Ultrasound Imaging

An acoustic metamaterial and ultrasonic imaging technology, which is applied in the field of acoustic metamaterials to achieve great application value and eliminate dissipation and distortion effects.

Active Publication Date: 2022-07-19
ZHEJIANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

In short, the skull has a strong attenuation and distortion effect on ultrasound, and it is difficult for ultrasound to effectively penetrate the skull to achieve intracranial tissue and blood flow imaging in conventional ways

Method used

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  • A Double Negative Acoustic Metamaterial Based on Mie Resonance for Transcranial Ultrasound Imaging
  • A Double Negative Acoustic Metamaterial Based on Mie Resonance for Transcranial Ultrasound Imaging
  • A Double Negative Acoustic Metamaterial Based on Mie Resonance for Transcranial Ultrasound Imaging

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] The density of porous hydrogel microspheres is 500kg / m 3 , the speed of sound is 120m / s, the radius is 50μm; the density of the ultrasonic couplant is 900kg / m 3 , the sound speed is 1400m / s; the porous hydrogel microspheres are uniformly dispersed in the ultrasonic couplant matrix to obtain the desired double negative acoustic metamaterial, in which the volume fraction of the porous hydrogel microspheres is 15%. The variation curves of equivalent mass density and equivalent elastic modulus with frequency calculated based on the multiple scattering model are as follows: image 3 As shown, the acoustic metamaterial exhibits both negative equivalent mass density and negative equivalent elastic modulus at frequencies from 0.63 to 0.67 MHz.

Embodiment 2

[0034] The density of porous hydrogel microspheres is 600kg / m 3 , the speed of sound is 150m / s, the radius is 60μm; the density of the ultrasonic couplant is 1000kg / m 3 , the sound speed is 1500m / s; the porous hydrogel microspheres are uniformly dispersed in the ultrasonic couplant matrix to obtain the desired double negative acoustic metamaterial, in which the volume fraction of the porous hydrogel microspheres is 20%. The variation curves of equivalent mass density and equivalent elastic modulus with frequency calculated based on the multiple scattering model are as follows: Figure 4 As shown, the acoustic metamaterial exhibits both negative equivalent mass density and negative equivalent elastic modulus at frequencies from 0.67 to 0.70 MHz.

Embodiment 3

[0036] The density of porous hydrogel microspheres is 700kg / m 3 , the speed of sound is 180m / s, the radius is 70μm; the density of the ultrasonic couplant is 1100kg / m 3 , the sound speed is 1600m / s; the porous hydrogel microspheres are uniformly dispersed in the ultrasonic couplant matrix to obtain the desired double negative acoustic metamaterial, in which the volume fraction of the porous hydrogel microspheres is 25%. The variation curves of equivalent mass density and equivalent elastic modulus with frequency calculated based on the multiple scattering model are as follows: Figure 5 As shown, the acoustic metamaterial exhibits both negative equivalent mass density and negative equivalent elastic modulus at frequencies from 0.68 to 0.73 MHz.

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Abstract

The invention discloses a double negative acoustic metamaterial for transcranial ultrasound imaging based on Mie resonance. The double negative acoustic metamaterial comprises an ultrasonic coupling agent as a matrix and a matrix dispersed in the matrix for generating mic The scatterer of the resonance, the scatterer is a porous polyethylene glycol diacrylate hydrogel microsphere; the volume fraction of the porous polyethylene glycol diacrylate hydrogel microsphere in the matrix is ​​15-25 %. The double negative acoustic metamaterial provided by the invention can effectively eliminate the dissipation and distortion of the skull on the sound wave, so it is expected to realize transcranial ultrasound imaging without relying on the naturally existing or artificial acoustic window of the skull.

Description

technical field [0001] The invention belongs to the field of acoustic metamaterials, in particular to a double negative acoustic metamaterial based on Mie resonance for transcranial ultrasound imaging. Background technique [0002] In the medical field, magnetic resonance imaging (MRI), computed tomography (CT) and brain ultrasound are the main imaging diagnostic methods for brain diseases. Although MRI is generally considered to be the most suitable method for brain examination, and CT also has its excellent diagnostic value, in some cases, brain ultrasound has an irreplaceable role. First, cranial ultrasound can provide hemodynamic information that cannot be obtained by MRI and CT; secondly, cranial ultrasound equipment is portable and suitable for bedside detection and long-term dynamic monitoring in emergency departments such as ambulances, emergency rooms, and intensive care units. In particular, bedside examinations can be performed for critically ill patients who can...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G10K11/162G10K11/172C08L83/04C08L55/00C08J9/08
CPCG10K11/172G10K11/162C08J9/08C08J2383/04C08J2455/00C08J2203/02
Inventor 黄玉辉吴勇军金一铭陈洁
Owner ZHEJIANG UNIV
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