Chewable tablet containing ambroxol hydrochloride and clenbuterol hydrochloride and preparation method of chewable tablet
A technology of clenbuterol hydrochloride and ambroxol hydrochloride, which is applied to medical preparations containing active ingredients, medical preparations with non-active ingredients, and pharmaceutical formulas to achieve broad market prospects and social benefits, improve stability, The effect of increasing adherence
Active Publication Date: 2020-06-30
南京嘉晨医药科技有限公司
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- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
The oral solid preparation containing ambroxol hydrochloride and clenbuterol hydrochloride active ingredients of this invention has the characteristics of being stable on placement, but it has been found through experiments that its stability still has a lot of room for improvement
Method used
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Examples
Experimental program
Comparison scheme
Effect test
Embodiment 1-6
[0037] The composition of embodiment 1-6 is as shown in table 1:
[0038] Table 1.
[0039]
Embodiment 7
[0041] Different from embodiment 2, embodiment 7 selects talcum powder as lubricant for use, all the other are all the same.
Embodiment 8
[0043] Unlike Example 2, Example 8 selects stearic acid as the lubricant, and all the others are the same.
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The invention discloses a chewable tablet containing ambroxol hydrochloride and clenbuterol hydrochloride and a preparation method of the chewable tablet, and belongs to the technical field of pharmaceutical preparations. The chewable tablet comprises the following components in parts by weight: 15-30 parts of ambroxol hydrochloride, 0.01-0.1 part of clenbuterol hydrochloride, 220-440 parts of medicinal auxiliary materials, 2.5-5 parts of a flavoring agent and 2.5-5 parts of a lubricant, wherein the weight part ratio of the ambroxol hydrochloride to the clenbuterol hydrochloride is 1500:(0.5-5). The chewable tablet exerts the synergistic effect of ambroxol hydrochloride and clenbuterol hydrochloride on relieving symptoms such as dyspnea and the like caused by airway obstructive diseases such as bronchial asthma, chronic bronchitis, emphysema and the like, and stability is further improved. The chewable tablet has little component change in a certain time, has good taste, is easy to carry and has a wide market prospect and social benefit.
Description
technical field [0001] The invention belongs to the technical field of pharmaceutical preparations, in particular to a chewable tablet containing ambroxol hydrochloride and clenbuterol hydrochloride and a preparation method thereof. Background technique [0002] Due to factors such as air pollution, smoking, inhalation of physical and chemical factors and biological factors caused by industrial economic development, and population aging, the incidence of respiratory diseases such as lung cancer and bronchial asthma has increased significantly in recent years, and chronic obstructive pulmonary disease has remained high (40 over 8% of the population over the age of 10). With the improvement of people's living standards and the continuous deterioration of the environment, the incidence of respiratory diseases is getting higher and higher. Patients also need more drugs with definite curative effect, stable quality and convenient administration. [0003] The chemical name of amb...
Claims
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Patent Timeline
Login to View More IPC IPC(8): A61K9/20A61K31/137A61K47/38A61P11/06A61P11/00
CPCA61K9/2054A61K9/0056A61K31/137A61P11/06A61P11/00A61K2300/00
Inventor 张用杰
Owner 南京嘉晨医药科技有限公司