Multi-gene family identification and evolution analysis method

A gene family and evolutionary analysis technology, applied in the field of biological information analysis, can solve the problems of limited analysis range, high cost, cumbersome operation, etc., and achieve the effect of mature analysis method, high accuracy and high efficiency
CN111445954AActive Publication Date: 2020-07-24GUANGZHOU GENE DENOVO BIOTECH
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
GUANGZHOU GENE DENOVO BIOTECH
Publication Date
2020-07-24

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Abstract

The invention provides a multi-gene family identification and evolution analysis method. The method is an independent analysis technology or a joint analysis technology for target species and homologous species. The independent analysis method comprises the steps of protein gene family identification, protein gene family structure information analysis, family gene member chromosome distribution analysis, replication gene event prediction, Motif analysis and protein gene family evolutionary tree analysis. The joint analysis method comprises the following analysis processes: protein gene familyidentification, protein gene family evolutionary tree analysis, Ka / Ks analysis, gene selective evolution analysis and colinearity analysis. The method does not need design of primers, PCR amplification and construction of a genome library; the analysis process is mature, the period is short, the yield is high; analysis results are confirmed through two databases of Pfam and SMART, and the accuracyrate is high; and the method is suitable for DNA sequencing data or protein sequences.
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Description

technical field

[0001] The invention relates to the field of biological information analysis of gene sequence information and protein sequences, in particular to a cross-species, multi-dimensional, comprehensive multi-gene family identification and systematic method for evolution analysis. Background technique

[0002] A gene family is a group of genes derived from the same ancestor and produced two or more copies of a gene through gene duplication. They have obvious similarities in structure and function, encoding similar protein products. The exon sequences of genes in the same family are related, therefore, the proteins encoded by these genes have similar amino acid sequences, structural domains and functions, and these proteins are called protein families. At present, most commonly used gene family analysis methods only analyze one aspect of gene structure, replication type or evolutionary tree analysis, and there is no systematic and comprehensive bioinformatics analys...

Claims

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