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Composition capable of being used for weight control and reversing atherosclerosis

A technology for atherosclerosis and weight control, applied in the formulation of food for specific medical purposes

Inactive Publication Date: 2020-08-14
北京易思腾翻译服务有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

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Method used

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  • Composition capable of being used for weight control and reversing atherosclerosis
  • Composition capable of being used for weight control and reversing atherosclerosis
  • Composition capable of being used for weight control and reversing atherosclerosis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Mix 60g of xylitol, 0.5g of orange essence, 0.1g of orange pigment, 10g of silicon dioxide, 10g of magnesium stearate and 19.4g of light calcium carbonate powder to form 100g of solid matrix.

[0023] Add 600 g of L-ascorbyl palmitate, 200 g of lotus leaf extract, 50 g of L-ascorbic acid, 50 g of proline and 50 g of lysine in the 50 g of matrix, and stir while adding, so that they are uniformly mixed with the matrix. That is, 1000 g of the powdery composition was obtained.

Embodiment 2

[0025] Mix 900g of soybean oil, 5g of sucrose ester, 15g of monoglyceride, and 80g of water evenly to form 1000g of liquid base.

[0026] Add 300 g of L-ascorbyl laurate, 200 g of lotus leaf extract, 50 g of L-ascorbic acid, 20 g of proline, 15 g of histidine and 15 g of lysine into the 400 g of the base, and stir while adding to mix them with the base uniform. That is, 1000 g of the liquid present composition was obtained.

Embodiment 3

[0028] Get the original powder of lotus leaf extract and an appropriate amount of the composition prepared in Example 1, place in potassium phosphate buffer containing 0.5% sodium carboxymethylcellulose, ultrasonically disperse and boil, and prepare 60 mg / mL (based on lotus leaf extract) solution, stored at 4°C after cooling for later use.

[0029] Dilute the above lotus leaf extract solution and the composition solution prepared in Example 1 with potassium phosphate buffer to a diluent (25 mg / L), then each take 35 μL and orlistat solution (25 mg / L, positive control) , Potassium phosphate buffer (blank) 35 μL in a 96-well plate, and add 15 μL of porcine pancreatic lipase solution (1 g / L) prepared in potassium phosphate buffer, incubate at room temperature for 10 minutes, then add 4-methylumbelliferyl oleic acid Ester (4-MUO) (0.1mmol / L) 50μL, dynamic fluorescence measurement was performed at 37°C. The excitation wavelength and absorption wavelength are 320 and 450 nm, respect...

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Abstract

The invention belongs to the technical field of formulas of foods for specific medical purposes. The invention particularly relates to a composition capable of being used for weight control and reversing atherosclerosis. The invention provides a formula food with specific medical application, which can reverse atherosclerosis and has good effects of losing weight, reducing blood fat and controlling postprandial blood sugar. By inhibiting intestinal pancreatic lipase, the oral bioavailability of L-ascorbyl fatty acid ester is greatly improved, the effect of reversing atherosclerosis of L-ascorbyl fatty acid ester is exerted, and the health-care effect of controlling body weight can be achieved by preventing digestion and absorption of fat; meanwhile, the health-care effects of controlling postprandial blood sugar and more effectively controlling body weight are achieved by preventing digestion and absorption of starch, any toxic or harmful risk is avoided, and wide application prospectsare achieved in the public health field of controlling body weight and preventing cardiovascular and cerebrovascular diseases.

Description

technical field [0001] The invention belongs to the technical field of formulation of food for specific medical use. Specifically, it belongs to a composition useful for weight control and reversible atherosclerosis. Background technique [0002] Cardiovascular and cerebrovascular diseases are collectively referred to as cardiovascular and cerebrovascular diseases. disease. Cardiovascular and cerebrovascular disease is a common disease that seriously threatens the health of human beings, especially middle-aged and elderly people over 50 years old. It has the characteristics of high prevalence, high disability rate and high mortality rate. However, there are still more than 50% of cerebrovascular accident survivors who cannot take care of themselves completely. The number of cardiovascular and cerebrovascular diseases in the world is as high as 15 million people every year, ranking first among various causes of death. [0003] The incidence of cardiovascular and cerebrovas...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K45/06A61K31/375A61K31/198A61K31/401A61K31/4172A61K36/62A61P3/04A61P9/10A61P3/10A61P3/06A23L33/12A23L33/10A23L33/105A23L33/15A23L33/175
CPCA23V2002/00A61K31/198A61K31/375A61K31/401A61K31/4172A61K36/62A61K45/06A23L33/10A23L33/105A23L33/12A23L33/15A23L33/175A61P3/04A61P3/06A61P3/10A61P9/10A61K2300/00A23V2200/326A23V2200/3262A23V2200/328A23V2200/332A23V2250/063A23V2250/064A23V2250/1578A23V2250/1628A23V2250/18A23V2250/21A23V2250/6422A23V2250/708A23V2250/0624A23V2250/192
Inventor 汤鲁宏汤宁
Owner 北京易思腾翻译服务有限公司
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