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Composite material and its preparation method and use

A technology of composite materials and mixed solvents, which is applied in the preparation of composite materials and the field of composite materials for repairing dental hard tissues, which can solve problems such as low patient adaptability, oral bacterial erosion of materials, and difficulty in matching the properties of the surrounding original dental hard tissues.

Active Publication Date: 2022-03-22
SICHUAN UNIV
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Problems solved by technology

At the same time, although different types of artificial restoration materials including resin, metal, ceramic and composite materials have been widely used clinically, these materials are easily eroded by oral bacteria and difficult to match the properties of the surrounding original tooth hard tissue, making the current To a certain extent, the treatment methods have problems such as low patient adaptability, poor long-term treatment effect and secondary dental caries.

Method used

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  • Composite material and its preparation method and use
  • Composite material and its preparation method and use
  • Composite material and its preparation method and use

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Embodiment Construction

[0025] An ideal tooth hard tissue restoration material faces a key scientific problem: how to realize the effective interface interaction between the material and the original tooth hard tissue in the complex environment of the oral cavity, especially in the bacterial environment, and finally rebuild and maintain the tooth for a long time hard tissue structure.

[0026] The formation of dental hard tissue is a biomineralization process, which is regulated by the organic components in the organism. These organic components mainly include hydrophobic macromolecules and acidic macromolecules. Among them, hydrophobic macromolecules such as collagen molecules form a hydrophobic matrix through self-assembly and other methods, which serve as the basic structural framework for mineralization, while acidic macromolecules immobilized on the hydrophobic matrix attract mineral ions in the solution to gather in the organic matrix. , and finally rely on the structure, charge and stereochem...

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Abstract

The invention provides a composite material and its preparation method and application. The preparation method comprises: obtaining polyamino acid, polyamino acid comprises hydrophilic polyamino acid and hydrophobic polyamino acid, hydrophilic polyamino acid contains hydrophilic segment, and hydrophobic polyamino acid contains hydrophobic segment; obtains zein and tannic acid nanoparticles; The amino acid is grafted to the zein and tannin nanoparticles; the carboxyl group of the polyamino acid grafted to the zein and the tannin nanoparticles is modified by using a cross-linking agent to obtain a composite material. The invention can realize strong adsorption of tooth surface / saliva acquired film underwater, cross-linking to form plaque biofilm, and biomineralization.

Description

technical field [0001] The technical field of materials of the present invention, more specifically, relates to a composite material for repairing dental hard tissue, a preparation method and application of the composite material. Background technique [0002] Oral health is one of the important indicators to measure the physical and mental health of residents. Dental hard tissue in oral tissue is the hardest part of the human body. It is characterized by high mineralization, low organic matrix content, and lack / minimal content of differentiated Active cells, so it is difficult for mature dental hard tissue to repair itself after damage. However, damage to dental hard tissues due to mechanical wear, bacteria or acidic beverages is very common. Taking children's dental caries as an example, the fourth national oral epidemiological survey released in 2018 showed that the caries rate of deciduous teeth of 5-year-old children and permanent tooth caries of 12-year-old children w...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K6/891A61K6/62A61K6/69
CPCA61K6/891A61K6/62A61K6/69C08L87/00
Inventor 杨佼佼李继遥侯嫒琳何利邦梁坤能
Owner SICHUAN UNIV
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