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High-capture efficiency device for simultaneously controlling low-refractive-index particles in multiple Rayleigh regions

A low-refractive-index, particle-based technology, applied in the field of new optical tweezers capture devices, can solve problems such as the inability to independently capture multiple low-refractive-index particles at the same time

Active Publication Date: 2020-10-23
ZHEJIANG UNIV +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0006] The purpose of the present invention is to overcome the problem that the existing single-beam optical tweezers technology cannot capture multiple low-refractive index particles independently on the same plane at the same time, and proposes a device that simultaneously manipulates low-refractive index particles in the Rayleigh region and can improve the capture efficiency And the processing method, the amplitude or phase of the beam is modulated by the spatial light modulator, which can realize the trapping of multiple particles and manipulate each particle at the same time

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  • High-capture efficiency device for simultaneously controlling low-refractive-index particles in multiple Rayleigh regions
  • High-capture efficiency device for simultaneously controlling low-refractive-index particles in multiple Rayleigh regions
  • High-capture efficiency device for simultaneously controlling low-refractive-index particles in multiple Rayleigh regions

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Embodiment Construction

[0038] In order to make the purpose, technical solution and advantages of the present application clearer, the present invention will be further described below in conjunction with the accompanying drawings and examples. The implementation of the present invention includes but not limited to the following examples. Based on the embodiments of the present application, all other embodiments obtained by persons of ordinary skill in the art without creative efforts fall within the protection scope of the present application.

[0039] The present invention will be further described below in conjunction with the accompanying drawings.

[0040] Such as figure 1 As shown, the specific implementation device includes a laser 1, a beam expander group 2, a transmission spatial light modulator 3, a graphic controller 4, a well adjustment mirror 5, a dichroic beam splitter 6, a high-focus objective lens 7, and a sample chamber 8 , an illuminating lamp 9 and a CCD detector 10; an illuminati...

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Abstract

The invention discloses a high-capture efficiency device for simultaneously controlling low-refractive-index particles in multiple Rayleigh regions. A light beam emitted by a laser device enters a transmission type spatial light modulator after being expanded by a beam expander set, and enters a double-color beam splitter through a trap position adjusting mirror to be reflected to a high-focusingobjective lens, then focused light can be outputted; the focused light enters a sample chamber to form light traps and irradiates a sample in the sample chamber; the sample chamber is filled with a plurality of particles; an illuminating lamp illuminates and penetrates through the sample chamber to irradiate the focus of the high-focus objective lens, and scattered light generated by irradiating the sample in the sample chamber by the focused light returns and is imaged on the target surface of a CCD detector. According to the device of the invention, the transmission-type spatial light modulator is controlled to generate a sinusoidal modulation Gaussian beam of multiple position light traps, so that new light intensity distribution is obtained; particles with high and low refractive indexes are stably captured within the range of a focus area; the multiple particles can be independently controlled at the same time; and the gradient force of the optical traps is improved by selecting asinusoidal modulation coefficient g, and therefore the capturing efficiency is improved.

Description

technical field [0001] The invention relates to a new type of optical tweezers capture device belonging to the technical field of optical capture and far-field manipulation of particles, and proposes a device that can simultaneously and independently capture low-refractive-index particles and improve capture efficiency, which can be applied in cell microbiology It belongs to the field of optical tweezers application and the field of nanoparticle assembly. Background technique [0002] The purpose of establishing an optical tweezers device is to establish a high-gradient optical field capable of trapping particles, and then realize the transport of particles through the relative movement between the particles and the environment where the light is located. Scientists have begun to have great interest in the potential excellent performance of light-harvesting technology at the micro-nano scale and its wide application in the field of cell biology. The trapping properties of a...

Claims

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Application Information

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IPC IPC(8): G21K1/00
CPCG21K1/00
Inventor 陈杏藩苏晶晶李楠胡慧珠
Owner ZHEJIANG UNIV
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