Application of Annona muricata fruit extract in preparation of anti-diabetic drugs or health-care products

Abstract

The invention provides an application of an Annona muricata fruit extract in preparation of anti-diabetic drugs or health care products. An extraction method of the Annona muricata fruit extract comprises the following steps of taking Annona muricata whole fruits, performing crushing, adding ethanol with the volume 5-10 times that of the crushed fruits, carrying out reflux extraction for 1-2 hours, performing repeated extraction for 2-4 times, combining extracting solutions, and performing concentrating under reduced pressure and drying in vacuum to obtain the Annona muricata fruit extract. The Annona muricata fruit extract provided by the invention can significantly reduce STZ-induced diabetic mouse blood sugar, and meanwhile enhance the sugar tolerance of the mouse body. In addition, theAnnona muricata fruit extract disclosed by the invention can reduce the levels of glycosylated hemoglobin and low-density lipoprotein of mice. Moreover, compared with root and leaf extracts, the Annona muricata fruit extract has a more obvious inhibition effect on alpha-glucosidase. The Annona muricata fruit extract disclosed by the invention can be better applied to preparation of the anti-diabetic drugs or the health-care products.

Description

technical field [0001] The invention relates to the technical field of soursop fruit, in particular to the application of a soursop fruit extract in the preparation of anti-diabetic medicine or health care product. Background technique [0002] Diabetes mellitus is caused by absolute or relative lack of insulin in the body, or a decrease in the sensitivity of target cells to insulin in the body. At present, worldwide, the prevalence and incidence of diabetes are rising sharply, and the incidence of type 2 diabetes accounts for about 90% of the total incidence of diabetes. Patients with type 2 diabetes are accompanied by abnormal metabolism of fat, protein and other substances in addition to glucose metabolism disorders, and have obvious symptoms of obesity. As the disease progresses, diabetic patients often cause multiple organ complications such as the heart, blood vessels, eyes, kidneys, and nerves, causing huge economic, social, and medical burdens on patients and societ...

AI Technical Summary

Problems solved by technology

But the soursop fruit is not easy to store after picking, the storage period is short, the ripe fruit is very soft, easy to squeeze and blacken, and there is loss of nutrition and flavor substances in the process of fruit production and processing

When the output of soursop fruit is excessive, it will lead to waste of resources, and it is urgent to improve its deep processing technology

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