A kind of anti-wrinkle composition gel for eyes and preparation method thereof
A composition and eye technology, which can be applied to cosmetic preparations, preparations for skin care, medical preparations containing active ingredients, etc., can solve the problems of weak and limited sustained and controlled release ability, and the contribution of reducing irritation, etc. To achieve the effect of good stability and good transdermal absorption
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Embodiment 1
[0043] Embodiment 1: A kind of preparation method of the anti-wrinkle composition gel for eyes:
[0044] Step 1: Weigh anti-wrinkle active substance, hydroxypropyl γ-cyclodextrin, PEG-12 polymethylsiloxane / PPG-20 cross-linked copolymer, glycerin according to the mass ratio of 5:0.5:15:25:30 and deionized water, the anti-wrinkle active substance is composed of acetyl hydroxyproline, carnosine, tocopherol glucoside, thiotaurine, and nicotinamide riboside in a mass ratio of 1:1:0.6:2:0.5;
[0045] Step 2: Mix 1 / 3 mass glycerin weighed in step 1 with acetyl hydroxyproline, tocopheryl glucoside, and nicotinamide ribose weighed in step 1, and stir evenly to obtain a mixed solution A;
[0046] Step 3: Mix the remaining 2 / 3 mass of glycerin and 1 / 2 mass of deionized water weighed in step 1 with the PEG-12 polymethylsiloxane / PPG-20 cross-linked copolymer, and mix well Liquid B;
[0047] Step 4: Mix and stir carnosine, thiotaurine and hydroxypropyl γ-cyclodextrin with the remaining de...
Embodiment 2
[0050] Embodiment 2: A preparation method of a wrinkle-removing composition gel for eyes:
[0051] Step 1: Weigh anti-wrinkle active substance, hydroxypropyl γ-cyclodextrin, PEG-12 polymethylsiloxane / PPG-20 cross-linked copolymer, glycerin according to the mass ratio of 6.0:1.0:18:30:25 and deionized water, the anti-wrinkle active substance is composed of acetyl hydroxyproline, carnosine, tocopherol glucoside, thiotaurine, and nicotinamide riboside in a mass ratio of 1:1.2:0.6:2:0.2;
[0052] Step 2: Mix 1 / 3 mass glycerin weighed in step 1 with acetyl hydroxyproline, tocopheryl glucoside, and nicotinamide ribose weighed in step 1, and stir evenly to obtain a mixed solution A;
[0053] Step 3: Mix the remaining 2 / 3 mass of glycerin and 1 / 2 mass of deionized water weighed in step 1 with the PEG-12 polymethylsiloxane / PPG-20 cross-linked copolymer, and mix well Liquid B;
[0054] Step 4: Mix and stir carnosine, thiotaurine and hydroxypropyl γ-cyclodextrin with the remaining deio...
Embodiment 3
[0057] Embodiment 3: A preparation method of a wrinkle-removing composition gel for eyes:
[0058] Step 1: Weigh anti-wrinkle active substance, hydroxypropyl γ-cyclodextrin, PEG-12 polymethicone / PPG-20 cross-linked copolymer, glycerin according to the mass ratio of 4.5:0.5:12:20:24 and deionized water, the anti-wrinkle active substance is composed of acetyl hydroxyproline, carnosine, tocopheryl glucoside, thiotaurine, and nicotinamide riboside in a mass ratio of 1:3:0.6:2:0.6;
[0059] Step 2: Mix 1 / 3 mass glycerin weighed in step 1 with acetyl hydroxyproline, tocopheryl glucoside, and nicotinamide ribose weighed in step 1, and stir evenly to obtain a mixed solution A;
[0060] Step 3: Mix the remaining 2 / 3 mass of glycerin and 1 / 2 mass of deionized water weighed in step 1 with the PEG-12 polymethylsiloxane / PPG-20 cross-linked copolymer, and mix well Liquid B;
[0061] Step 4: Mix and stir carnosine, thiotaurine and hydroxypropyl γ-cyclodextrin with the remaining deionized w...
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