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Wrinkle-removing composition gel for eyes and preparation method thereof

A composition and eye technology, applied in the direction of dressing preparations, skin care preparations, medical preparations containing active ingredients, etc., can solve the problem of not being able to load active ingredients at the same time, reduce the contribution of irritation, and slow and controlled release capabilities Weakness and other problems, to achieve the effect of removing eye wrinkles, enhancing stability, and strengthening the skin barrier

Active Publication Date: 2020-11-24
PROYA COSMETICS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Existing eye gels usually use hydroxypropyl methylcellulose, carbomer, etc. as carriers, but such hydrogels have weak slow and controlled release capabilities, and cannot simultaneously load multiple active ingredients with widely different properties , the contribution to reducing irritation is also limited

Method used

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  • Wrinkle-removing composition gel for eyes and preparation method thereof
  • Wrinkle-removing composition gel for eyes and preparation method thereof
  • Wrinkle-removing composition gel for eyes and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] Embodiment 1: A kind of preparation method of the anti-wrinkle composition gel for eyes:

[0044] Step 1: Weigh anti-wrinkle active substance, hydroxypropyl γ-cyclodextrin, PEG-12 polymethylsiloxane / PPG-20 cross-linked copolymer, glycerin according to the mass ratio of 5:0.5:15:25:30 and deionized water, the anti-wrinkle active substance is composed of acetyl hydroxyproline, carnosine, tocopherol glucoside, thiotaurine, and nicotinamide riboside in a mass ratio of 1:1:0.6:2:0.5;

[0045] Step 2: Mix 1 / 3 mass glycerin weighed in step 1 with acetyl hydroxyproline, tocopheryl glucoside, and nicotinamide ribose weighed in step 1, and stir evenly to obtain a mixed solution A;

[0046] Step 3: Mix the remaining 2 / 3 mass of glycerin and 1 / 2 mass of deionized water weighed in step 1 with the PEG-12 polymethylsiloxane / PPG-20 cross-linked copolymer, and mix well Liquid B;

[0047] Step 4: Mix and stir carnosine, thiotaurine and hydroxypropyl γ-cyclodextrin with the remaining de...

Embodiment 2

[0050] Embodiment 2: A preparation method of a wrinkle-removing composition gel for eyes:

[0051] Step 1: Weigh anti-wrinkle active substance, hydroxypropyl γ-cyclodextrin, PEG-12 polymethylsiloxane / PPG-20 cross-linked copolymer, glycerin according to the mass ratio of 6.0:1.0:18:30:25 and deionized water, the anti-wrinkle active substance is composed of acetyl hydroxyproline, carnosine, tocopherol glucoside, thiotaurine, and nicotinamide riboside in a mass ratio of 1:1.2:0.6:2:0.2;

[0052] Step 2: Mix 1 / 3 mass glycerin weighed in step 1 with acetyl hydroxyproline, tocopheryl glucoside, and nicotinamide ribose weighed in step 1, and stir evenly to obtain a mixed solution A;

[0053] Step 3: Mix the remaining 2 / 3 mass of glycerin and 1 / 2 mass of deionized water weighed in step 1 with the PEG-12 polymethylsiloxane / PPG-20 cross-linked copolymer, and mix well Liquid B;

[0054] Step 4: Mix and stir carnosine, thiotaurine and hydroxypropyl γ-cyclodextrin with the remaining deio...

Embodiment 3

[0057] Embodiment 3: A preparation method of a wrinkle-removing composition gel for eyes:

[0058] Step 1: Weigh anti-wrinkle active substance, hydroxypropyl γ-cyclodextrin, PEG-12 polymethicone / PPG-20 cross-linked copolymer, glycerin according to the mass ratio of 4.5:0.5:12:20:24 and deionized water, the anti-wrinkle active substance is composed of acetyl hydroxyproline, carnosine, tocopheryl glucoside, thiotaurine, and nicotinamide riboside in a mass ratio of 1:3:0.6:2:0.6;

[0059] Step 2: Mix 1 / 3 mass glycerin weighed in step 1 with acetyl hydroxyproline, tocopheryl glucoside, and nicotinamide ribose weighed in step 1, and stir evenly to obtain a mixed solution A;

[0060] Step 3: Mix the remaining 2 / 3 mass of glycerin and 1 / 2 mass of deionized water weighed in step 1 with the PEG-12 polymethylsiloxane / PPG-20 cross-linked copolymer, and mix well Liquid B;

[0061] Step 4: Mix and stir carnosine, thiotaurine and hydroxypropyl γ-cyclodextrin with the remaining deionized w...

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Abstract

The invention relates to wrinkle-removing composition gel for eyes and a preparation method thereof. The wrinkle-removing composition gel is characterized by being composed of a wrinkle-removing active substance, hydroxypropyl gamma-cyclodextrin, a PEG-12 (polyethylene glycol 12) polymethylsiloxane / PPG-20 cross-linked polymer, glycerol and de-ionized water at the mass ratio of (4-10):(0.5-2):(10-20):(20-30):(20-30), wherein the wrinkle-removing active substance is composed of acetyl hydroxyproline, carnosine, tocopheryl glucoside, 2-aminoethanethiosulfonic acid and nicotinamide ribose at the mass ratio of 1:(1-3):0.6:2:(0.2-0.8). The wrinkle-removing composition gel can be used for loading five wrinkle-removing components with different properties, namely the acetylhydroxyproline, the carnosine, the tocopheryl glucoside, the 2-aminoethanethiosulfonic acid and the nicotinamide ribose, and has the beneficial effects of good effect of removing wrinkles of the eyes, good stability and goodtransdermal absorption.

Description

technical field [0001] The invention relates to the technical field of cosmetic preparation, in particular to an anti-wrinkle composition gel for eyes and a preparation method thereof. Background technique [0002] Wrinkles are the most obvious basis for judging skin aging. They are usually around the eyes, corners of the mouth, and neck. Due to the special structure of the eyes, eye wrinkles appear relatively early, so they are often used to judge the degree of skin aging. The eye wrinkles located at the outer canthus, also known as crow’s feet, are arranged in a radial pattern. At first, they usually only appear when making facial expressions such as smiling. They are temporary wrinkles. The fibers lose their vitality, the amount of oil secreted by the sebaceous glands decreases, and the skin barrier function decreases and gradually becomes loose, which makes the eye wrinkles increase and form permanent wrinkles. Generally speaking, the wrinkle-removing effect of active s...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/67A61K8/49A61K8/64A61K8/46A61K8/04A61K8/894A61K8/73A61Q19/00A61Q19/08
CPCA61K8/042A61K8/466A61K8/4913A61K8/64A61K8/675A61K8/678A61K8/738A61K8/894A61K2800/592A61Q19/005A61Q19/08
Inventor 王晗宁毕永贤钱舒敏刘红艳王晓叶迎蒋丽刚
Owner PROYA COSMETICS