A drug for the prevention of oxidative stress in retinal ganglion cells and wet maculopathy

A technology of macular degeneration and drugs, applied in drug combinations, pharmaceutical formulas, sensory diseases, etc., can solve problems such as DNA tetrahedron or miR-155 that have not yet been seen, and achieve good application prospects, good protective effects, and prevention of cell apoptosis Effect
CN112007044BActive Publication Date: 2021-11-12CHENGDU GENREZE GENE TECH CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
CHENGDU GENREZE GENE TECH CO LTD
Publication Date
2021-11-12

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Abstract

The invention provides a medicine for preventing oxidative stress of retinal ganglion, which is a preparation prepared by taking DNA tetrahedron as active ingredient and adding pharmaceutically acceptable auxiliary materials or auxiliary ingredients. The invention also provides the use of the DNA tetrahedron in the preparation of medicines for preventing oxidative stress and apoptosis of retinal ganglion cells. The use of tFNA to prepare drugs for preventing oxidative stress of retinal ganglion cells will help to treat diseases caused by oxidative stress of retinal ganglion cells including glaucoma, and has a very good application prospect.
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Description

technical field

[0001] The invention relates to the field of retinal nerve medicine. Background technique

[0002] Oxidative stress (OS) refers to a state of imbalance between oxidation and anti-oxidation in the body, which tends to oxidize, leading to inflammatory infiltration of neutrophils, increased secretion of proteases, and production of a large number of oxidized intermediates. Oxidative stress is a negative effect of free radicals in the body and is believed to be an important factor in aging and disease.

[0003] Retinal ganglion cells are cells located in the innermost layer of the retina, whose main function is to receive electrical impulses transmitted from cones and rods to bipolar cells, and to transmit electrical impulses to the optic nerve to produce vision. Oxidative stress in retinal ganglion cells is involved in the pathological process of many diseases, including glaucoma, diabetes, age-related macular degeneration, optic nerve damage, etc. When retina...

Claims

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