A kind of external gel for skin wound and preparation method thereof

Abstract

The invention discloses an external gel for skin wounds, which is made of the following raw materials in parts by weight: 1-3 parts of active component A, 4-6 parts of active component B, 10-10 parts of calendula extract 14 parts, 16-20 parts of Centella asiatica extract, 60-80 parts of auxiliary materials; the active component A is at least two of polymyxin B sulfate, neomycin sulfate and bacitracin; the active component Part B is at least one of lidocaine hydrochloride, pramoxine hydrochloride, procaine hydrochloride and menthol; the auxiliary materials include the following raw materials in parts by weight: 0.5-3 parts of carbomer, organic solvent 40‑75 parts, 20‑50 parts of purified water. The gel for external use of the present invention has a preventive effect on bacterial infection of skin wounds, and has analgesic and hemostatic effects on skin wounds; it can also promote the formation of wound capillaries and collagen fibers, reduce the days of wound healing, and can be used for burns, cuts, For the healing of skin wounds such as burns, the healed skin is smooth, without scars, and the healing effect is good.

Description

[0001] 1. Technical field

[0002] The invention relates to the technical field of pharmaceutical preparations, in particular to an external gel for skin wounds and a preparation method thereof.

[0003] 2. Background technology

[0004] Skin is an important organ of the human body, composed of epidermis and dermis, and has important physical, chemical and biological barrier functions. Burns, cuts, and scalds are common skin wounds in peacetime and wartime; various damages caused by skin trauma, such as: increased metabolism, decreased body temperature, excessive loss of water and protein, and disorders of the endocrine and immune systems are all related to the skin barrier. related to loss of function.

[0005] Wound healing is a complex biological process, including cell proliferation, differentiation, epithelialization, migration, and matrix synthesis and deposition. In clinical practice, skin wounds are often treated by speeding up wound healing, preventing bacterial infe...

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