Antibody, reagent and kit for Kawasaki disease treatment effect evaluation and application of antibody, reagent and kit

A treatment effect, Kawasaki disease technology, applied in the direction of antibodies, anti-inflammatory agents, disease diagnosis, etc., to achieve the effect of reducing early misdiagnosis rate and reducing experience requirements
CN112159472AInactive Publication Date: 2021-01-01DAOZHI PRECISION MEDICINE TECH SHANGHAI CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
DAOZHI PRECISION MEDICINE TECH SHANGHAI CO LTD
Publication Date
2021-01-01
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses an antibody, a reagent and a kit for Kawasaki disease treatment effect evaluation and application of the antibody, the reagent and the kit. The antibody can be used as a markerfor Kawasaki disease treatment effect evaluation and can also be used for preparing a biomarker for high-risk judgment, a new thought is provided for clinical Kawasaki disease treatment effect evaluation, and the misdiagnosis rate of Kawasaki diseases can be reduced.
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Description

technical field

[0001] The invention relates to the field of biotechnology, in particular to an antibody, reagent, kit and application thereof for evaluating the therapeutic effect of Kawasaki disease. Background technique

[0002] Kawasaki disease (KD) was first reported by Japanese pediatrician Tomisaku Kawasaki in 1967. It is an acute, self-limited systemic vasculitis. The main clinical manifestations are fever, oral mucosal changes, rash, and cervical lymph nodes. Swelling, bulbar conjunctival hyperemia and extremity changes. Coronary artery lesion (CAL) caused by KD mainly includes coronary artery dilatation, coronary aneurysm, and later development of coronary artery stenosis. In severe cases, myocardial infarction, ischemic cardiomyopathy, and even sudden death may occur.

[0003] my country has a large population base and a large number of children under the age of 5. It belongs to the Asian population with a high incidence of Kawasaki disease. In recent years, the ...

Claims

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