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Plant compound capable of inhibiting acne-related pathogenic bacteria and application thereof

A compound and pathogenic bacteria technology, which is applied in the direction of drug combination, plant raw materials, plant/algae/fungus/moss components, etc., to achieve high-efficiency anti-acne effects, good market value and application prospects, and good application value.

Inactive Publication Date: 2021-01-05
YUNNAN BOTANEE BIO TECH GRP CO LTD +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Compared with the relevant reports of other researchers, there is no report on compounding Chonglou, rhubarb, and Magnolia officinalis into an acne-removing plant compound

Method used

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  • Plant compound capable of inhibiting acne-related pathogenic bacteria and application thereof
  • Plant compound capable of inhibiting acne-related pathogenic bacteria and application thereof
  • Plant compound capable of inhibiting acne-related pathogenic bacteria and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0066] A plant compound capable of inhibiting acne-related pathogenic bacteria, including the following components by weight: 20 parts of stem and leaf extract of Chonglou; 40 parts of Magnolia officinalis extract; for 100 copies.

[0067] The preparation process of the stems and leaves of Chonglou is as follows: Weigh an appropriate amount of dried medicinal materials of the stems and leaves of Chonglou, grind them and add them to the methanol / water mixture with a volume fraction of 40%, the feed solution of the dried medicinal materials of the stems and leaves of Chonglou and the methanol / water mixture The ratio is 1:15kg / L, reflux extraction twice at 75°C, the two extracts are combined, concentrated under reduced pressure and evaporated to dryness in a water bath in turn to obtain the crude extract of stems and leaves of Chonglou; the obtained crude extract of stems and leaves of Chonglou Separation and purification of HPD-100 macroporous resin to obtain the stem and leaf e...

Embodiment 2

[0071] A plant compound capable of inhibiting acne-related pathogenic bacteria, the following components by weight: 30 parts of stem and leaf extract of Chonglou; 30 parts of Magnolia officinalis extract; 100 copies.

[0072] The preparation process of the stems and leaves of Chonglou is as follows: Weigh an appropriate amount of dried medicinal materials of the stems and leaves of Chonglou, crush them and add them to a 50% butanediol / water mixture, and mix the dried stems and leaves of Chonglou with butanediol / water The solid-liquid ratio of the liquid is 1:10kg / L, and it is refluxed and extracted 3 times under the condition of 75°C, the obtained extracts are combined, concentrated under reduced pressure and evaporated to dryness in a water bath to obtain the crude extract of the stems and leaves of Chonglou; the obtained stems and leaves of Chonglou The crude extract is separated and purified by DM-301 macroporous resin to obtain the stem and leaf extract of Chonglou.

[00...

Embodiment 3

[0076] A plant compound capable of inhibiting acne-related pathogenic bacteria, the mass ratio of which is as follows: 40 parts of stem and leaf extract of Chonglou; 40 parts of Magnolia officinalis extract; share.

[0077] The preparation process of stems and leaves of Chonglou is as follows: Weigh an appropriate amount of dried medicinal materials of stems and leaves of Chonglou, grind them and add them to a methanol / water mixture with a volume fraction of 95%, the feed solution of dried stems and leaves of Chonglou and methanol / water mixture Ratio of 1:20kg / L, reflux extraction at 75°C for 2 times, combined the obtained extracts, concentrated under reduced pressure and evaporated to dryness in a water bath to obtain the crude extract of stems and leaves of Chonglou; the crude extract of stems and leaves of Chonglou obtained by Separation and purification of D101 macroporous resin to obtain the stem and leaf extract of Chonglou.

[0078] The preparation process of the Magno...

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Abstract

The invention discloses a plant compound capable of inhibiting acne-related pathogenic bacteria. The plant compound comprises the following components in parts by weight: 10-40 parts of paris polyphylla stem and leaf extract, 10-40 parts of mangnolia officinalis extract and 10-40 parts of rheum officinale extract, wherein the sum of the weight parts of the plant extracts is 100 parts. The plant compound has the excellent characteristics of high safety, capability of obviously inhibiting acne, and the like, and has excellent market value and application prospect. The invention also discloses anapplication of the plant compound capable of inhibiting acne-related pathogenic bacteria.

Description

technical field [0001] The invention relates to the technical field of cosmetics, in particular to a plant compound capable of inhibiting acne-related pathogenic bacteria and its application. Background technique [0002] Acne is one of the most common skin problems, also commonly known as acne, mainly due to the surge of male hormones during puberty, which causes the skin to secrete more oil components. In the event of microbial infection such as Propionibacterium acnes, It is very easy to cause inflammation, thereby forming different types of rashes such as acne, papules, and pustules. Moderate to severe acne will not only significantly affect the appearance of teenagers, but also have a great negative impact on the psychology and social interaction of teenagers. [0003] Currently commercially available anti-acne products often use some chemically synthesized or even antibiotic-based anti-acne ingredients to achieve anti-acne effects, and such anti-acne products often ha...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/896A61P31/04A61P17/10A61K8/9789A61K8/9794A61Q19/00
CPCA61K36/575A61K36/708A61K36/896A61Q19/00A61K8/9789A61K8/9794A61P17/10A61P31/04A61K2300/00
Inventor 王飞飞吴信浪曲丽萍马骁高绍阳郭振宇
Owner YUNNAN BOTANEE BIO TECH GRP CO LTD
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