A json-based gene ontology mapping system and method

A technology of gene ontology and mapping method, applied in transmission systems, electrical components, database design/maintenance, etc., to achieve the effect of reducing occupancy rate, efficient and full sharing, and improving data transmission efficiency

Active Publication Date: 2022-05-03
NANKAI UNIV
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Problems solved by technology

[0004] Aiming at the bottleneck problem of gene ontology data interaction and sharing among heterogeneous web platforms caused by lack of effective mapping mechanism, the present invention provides a JSON-based gene ontology mapping system and method

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  • A json-based gene ontology mapping system and method
  • A json-based gene ontology mapping system and method

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specific Embodiment approach

[0023] like figure 2 As shown, the JSON-based Gene Ontology mapping system consists of five cores: Gene Ontology data preprocessing, data extraction, data conversion, data storage, and visualization. The operating terminals include client web pages and mobile terminals. The specific implementation is as follows:

[0024] (1) Through the operation terminal, the user uploads the gene ontology to the server for management through the network.

[0025] (2) The data preprocessing module receives the operation terminal processing request, initializes the server-side gene ontology object, loads the gene ontology data, and identifies the multi-granularity metadata information of the gene ontology.

[0026] (3) The data extraction module will combine the semi-supervised learning method to extract the gene ontology hierarchical relationship, category features and metadata-attribute value and other metadata information layer by layer.

[0027] (4) The data conversion module will map t...

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Abstract

The invention discloses a JSON-based gene ontology mapping system and method, including automatic identification and data extraction of gene ontology, a mapping mechanism from gene ontology to JSON, and JSON-based gene ontology data storage. The specific steps are: identify the metadata information in the Gene Ontology, and obtain the three categories of cellular component, molecular function, and biological process in the Gene Ontology metadata, as well as the parent-child relationship (is_a) , part_of and regulation relationship (regulates) three relationship features; establish one-to-one mapping rules between gene ontology metadata features and JSON model, and use semi-supervised learning method to complete metadata extraction; build JSON-based gene ontology storage Model to complete the data migration from Gene Ontology to JSON. The invention establishes a mapping model of gene ontology and JSON, solves the problem that gene ontology data cannot be automatically converted into JSON data, and realizes efficient data interaction and full sharing of gene ontology among heterogeneous Web platforms.

Description

technical field [0001] The invention relates to data migration and ontology mapping technology, in particular to a JSON-based gene ontology mapping system and method. Background technique [0002] After the completion of the 21st Century Human Genome Project, major developed countries represented by the United States have launched a large number of life science basic research programs, driving the explosive growth of various genomics, disease and other related biological databases. Due to the differences in the data description methods of various biological databases, there is a large amount of semantically heterogeneous information. In order to make full use of the knowledge contained in these biological databases, biological ontologies are widely used in academia and industry to integrate heterogeneous biological knowledge. As a widely used biological ontology, Gene Ontology is mainly used to describe the attributes of genes and gene products, such as cellular components,...

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): H04L67/02H04L67/06H04L67/565H04L67/563G06F16/21
CPCH04L67/02H04L67/06G06F16/214H04L67/563H04L67/565
Inventor 刘健陈娇陈萍
Owner NANKAI UNIV
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