Gene selection method and device

A gene selection, gene data technology, applied in genomics, character and pattern recognition, instrumentation, etc., can solve problems such as difficulty in maintaining an effective balance between exploration and development

Pending Publication Date: 2021-01-12
WENZHOU UNIVERSITY
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AI Technical Summary

Problems solved by technology

However, in the process of gene screening, SCA still has a high room for improvement in the convergence speed and convergence accuracy of the optimized solution.
In this case, it is difficult to maintain an effective balance between exploration and development

Method used

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  • Gene selection method and device
  • Gene selection method and device
  • Gene selection method and device

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Embodiment Construction

[0049] In order to make the object, technical solution and advantages of the present invention clearer, the present invention will be further described in detail below in conjunction with the accompanying drawings.

[0050] According to a preferred embodiment of the present invention, such as figure 1 Shown, provide a kind of gene selection (screening) method, described method comprises the following steps:

[0051] Step S1. Obtain a training set and a test set through the genetic data microarray dataset, and determine the initial population;

[0052] Step S2, performing binary coding on each characteristic value of each individual of the current population using a conversion function;

[0053] Step S3, calculating the fitness value of the current population, and updating the relevant parameters in the salp and moth flame-fighting strategies;

[0054] Step S4, setting the relevant parameters of the sine-cosine optimization algorithm, and updating the population using the ite...

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Abstract

The invention provides a gene selection method which is used for gene characteristic selection. The method comprises the steps of obtaining a training set and a test set through a gene data microarraydata set, and determining an initialized population; carrying out binary coding on each individual of the current population by adopting a conversion function; calculating the fitness value of the current population, and updating related parameters in the dolio-sea squirt and moth fire suppression strategy; setting related parameters of a sine and cosine optimization algorithm, and updating the population by adopting a sine and cosine optimization algorithm iterative formula; updating the populations obtained through the sine and cosine optimization algorithm through a doliola scabra, moth fire suppression and reverse learning strategy in sequence so as to obtain three populations; selecting a next generation of population through greedy selection; and if the maximum number of iterationsis reached, ending the loop and outputting the optimal solution, otherwise, continuing the iteration until the iterative computation is ended. According to the invention, the gene characteristics which contribute most to categories can be screened out from the genes more accurately and more efficiently, and the detection cost is reduced.

Description

technical field [0001] The invention relates to a gene selection technology in the field of data preprocessing, in particular to a gene selection method. Background technique [0002] In today's competitive world where human beings are affected by various diseases especially cancer, leukemia, etc., medical tests help to determine the symptoms and causes of various diseases. With the rapid development of related technologies in the field of biomedicine and health, a large amount of bioinformatics and clinical medical data, especially molecular biology experiment data and genetic data, are growing at an unprecedented rate. Although humans have studied the occurrence and development of various diseases at the molecular level and found a large number of disease-causing genes, people still have little understanding of their occurrence and regulation mechanisms. The analysis of microarray gene expression data and protein expression data can be used to grasp the information of phy...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G06K9/62G06N3/00G16B20/20G16B40/00
CPCG06N3/006G16B20/20G16B40/00G06F18/214
Inventor 陈慧灵周伟汪鹏君
Owner WENZHOU UNIVERSITY
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