Traditional Chinese medicine composition and application thereof in preparation of drug for treating IR

A kind of composition and medicine technology, applied in the field of application in the preparation of IR medicines
CN112294893AInactive Publication Date: 2021-02-02SHANGHAI TONGREN HOSPITAL
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
SHANGHAI TONGREN HOSPITAL
Publication Date
2021-02-02
Estimated Expiration
Not applicable · inactive patent

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Abstract

The application provides a traditional Chinese medicine composition and application thereof in preparation of a drug for treating IR and relates to the field of traditional Chinese medicines. The traditional Chinese medicine composition comprises: 30g of raw milkvetch roots, 30g of radix puerariae, 9g of raw radix notoginseng, 9g of rhizoma coptidis, 30g of raw rehmannia roots, 15g of radix angelicae sinensis, 30g of raw white peony roots, 30g of panicled swallowwort roots and 15g of corydalis tubers. The traditional Chinese medicine composition can be applied to preparation of drugs for treating insulin resistance, particularly insulin resistance of post-stroke myospasm sufferers; it is verified that after the composition is taken, motor functions of affected limbs of the post-stroke myospasm sufferer are restored obviously, and fasting blood-glucose, fasting insulin and insulin resistance levels are all improved effectively; and it is confirmed that the traditional Chinese medicine composition can be applied to the preparation of the drugs for treating the insulin resistance of the post-stroke myospasm sufferers.
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Description

technical field

[0001] The application relates to a traditional Chinese medicine composition, especially the application of the composition in the preparation of medicine for treating IR. Background technique

[0002] Insulin resistance (IR for short) refers to the reduction or loss of the responsiveness of the target organs and tissues of insulin to its biological effects, mainly manifested in the weakened ability of insulin to promote the uptake and utilization of glucose in peripheral tissues (fat, muscle tissue) and Decreased efficacy of inhibiting glycogen export (Morita Yutaro, Senokuchi Takafumi, Yamada Sarie, Wada Toshiaki, Furusho Tatsuya, Matsumura Takeshi, IshiiNorio, Nishida Saiko, Nishida Syuhei, Motoshima Hiroyuki, Komohara Yoshihiro & Araki Eiichi (2020). Impact of tissue peripliferation on macrophage systemic insulin resistance in obese mice with diabetes. 8(1):10.1136 / bmjdrc-2020-001578). Its occurrence is related to multiple links and multi-level obstacles...

Claims

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