Application of tiratrocol to treatment of coxsackie virus infection

A technology of coxsackie virus and tiratricol, which is applied in the directions of antiviral agents, medical preparations containing active ingredients, pharmaceutical formulations, etc., and can solve the problem that there is no coxsackie virus inhibited by tiratricol.
CN112336708AActive Publication Date: 2021-02-09BEIJING UNIV OF CHEM TECH
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
BEIJING UNIV OF CHEM TECH
Publication Date
2021-02-09

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Abstract

The invention discloses an application of tiratrocol to treatment of coxsackie virus infection. The invention provides an application of the tiratropine or derivatives thereof or pharmaceutically acceptable salts thereof or substances taking tiratropine or derivatives thereof or pharmaceutically acceptable salts thereof as active ingredients in any one of the following aspects: inhibiting coxsackie virus, treating diseases caused by coxsackie virus infection, and improving the symptoms caused by coxsackie virus infection. Based on a coxsackie virus drug screening model, an anti-coxsackie virusactive drug namely tiratrocol is screened from commercially available drugs. The tiratrocol has important clinical application value for treating diseases infected with the coxsackie virus.
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Description

technical field

[0001] The invention relates to the field of medicines, in particular to the application of teiratracol in the treatment of Coxsackie virus infection. Background technique

[0002] Coxsackievirus (Coxsackievirus) is an enterovirus (enterovirus), which belongs to the Picornaviridae family and the genus Enterovirus. Its biological properties are similar to those of poliovirus, the diameter of the virion is 28nm, there is no envelope structure and the nucleic acid is single positive strand RNA. Coxsackie virus is a common virus that infects the human body through the respiratory tract and digestive tract. After infection, people will have cold symptoms such as fever, sneezing, and coughing. In severe cases, it can cause aseptic meningitis. According to the observation of the pathogenicity of the virus in the early stage of neonatal mouse infection, Coxsackie virus can be divided into two types: A and B. Among them, type A is more common in children and tends to...

Claims

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