Orthopaedic implantation instrument with osteogenesis promoting coating on surface and preparation method

A technology that promotes bone and equipment. It is used in coatings, medical science, prostheses, etc. It can solve the problems of surgical failure, easy loosening, and lack of osseointegration performance. It is beneficial to adhesion, promotes cell proliferation, and improves Effects of insufficient osseointegration
CN112402693APending Publication Date: 2021-02-26SHANGHAI CITY JIADING DISTRICT CENT HOSPITAL
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
SHANGHAI CITY JIADING DISTRICT CENT HOSPITAL
Publication Date
2021-02-26

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Abstract

The invention provides an orthopaedic implantation instrument with an osteogenesis promoting coating on the surface and further discloses a preparation method of the orthopaedic implantation instrument. A polydopamine coating is arranged on the surface of a smooth orthopaedic implantation instrument base body or an orthopaedic implantation instrument base body with a micro-nano structure, and salidroside is fixed on the surface of the polydopamine coating to form the osteogenesis promoting coating. The preparation method of the orthopaedic implantation instrument comprises the following steps:1) pretreating the orthopaedic implantation instrument base body to obtain a smooth or micro-nano structure surface appearance on the surface; (2) after the orthopaedic implantation instrument base body is pretreated, adding the orthopaedic implantation instrument into a dopamine solution to react for a period of time to form the polydopamine coating on the surface of the orthopaedic implantationinstrument, then putting the orthopaedic implantation instrument into a solution containing the salidroside, and fixing the salidroside on the surface of the orthopaedic implantation instrument by utilizing the excellent bonding performance of the polydopamine coating on the surface of the orthopaedic implantation instrument; and 3) rinsing the material with deionized water, and naturally dryingthe rinsed material.
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Description

technical field

[0001] The invention belongs to the field of surface modification and drug slow release of medical devices, and in particular relates to an orthopedic implant device with a bone-promoting coating on the surface.

[0002] The present invention also relates to a method for preparing the above-mentioned orthopedic implant device. Background technique

[0003] Medical implants are very important for clinical bone defect repair. The demand for implants has increased dramatically over the past 5 years (the number of hip revisions has increased by 26% and is expected to reach 137% by 2030). Titanium (Ti) is a high-gloss transition metal with low density, high strength, high fracture toughness, biocompatibility and extremely strong corrosion resistance. Titanium implants have good mechanical properties, corrosion resistance and biocompatibility, and are widely used. However, titanium implants with smooth surfaces have no biological activity, so they do not have go...

Claims

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