Synthesis method and application of PASP derivative with surface activity

Abstract

The invention discloses a synthesis method of a PASP derivative with surface activity. The synthesis method comprises the following steps: s1, synthesizing polysuccinimide; s2, synthesizing a polysuccinimide derivative grafted and modified by alkyl primary amine; s3, adding the alkyl primary amine modified polysuccinimide derivative into a hydrolysis kettle, adding water of which the mass is 3-6 times that of the polysuccinimide derivative, stirring and dispersing, slowly dropwise adding 2-5mol / L NaOH solution for hydrolysis under the heating and stirring maintaining conditions, and hydrolyzing at 35-65 DEG C for 2-6h to obtain a hydrolysate, namely an alkyl primary amine graft modified polyaspartate aqueous solution; and carrying out pH adjustment, filtration, ultrafiltration, concentration and purification for further refining. The method is simple and easy to operate, and the polymerization degree and the grafting rate are regulated and controlled by regulating and controlling the proportion and the chain length of the added alkyl primary amine compound. The synthesized alkyl primary amine modified polyaspartic acid derivative has excellent surface activity and chelating property, and has the effects of moisturizing, removing freckles, whitening, improving skin, removing heavy metals and the like.

Description

technical field [0001] The invention belongs to the technical field of PASP derivative synthesis, and more specifically relates to a synthesis method and application of a surface-active PASP derivative. Background technique [0002] Polyaspartic acid (referred to as PASP) is a biodegradable polyamino acid with carboxylic acid side chains. PASP and PASP derivatives are widely used in various fields. In skin care applications, PASP derivatives The synthesis method is complicated and difficult to operate, and its moisturizing, freckle-removing and other skin-improving effects are not good when used. Therefore, we propose a synthesis method of PASP derivatives with surface activity. Contents of the invention [0003] The purpose of the present invention is to solve the shortcomings in the prior art, and propose a method for synthesizing PASP derivatives with surface activity. [0004] In order to achieve the above object, the present invention provides the following technical...

AI Technical Summary

Problems solved by technology

[0002] Polyaspartic acid (referred to as PASP) is a biodegradable polyamino acid with carboxylic acid side chains. PASP and PASP derivatives are widely used in various fields. In skin care applications, PASP derivatives The synthesis method is complicated and difficult to operate, and its moisturizing, freckle-removing and other skin-improving effects are not good when used. Therefore, we propose a synthesis method of PASP derivatives with surface activity