Polysaccharide SM-0.4M and anti-tumor product prepared from polysaccharide SM-0.4M

A technology of polysaccharides and products, which is applied in the field of polysaccharide SM-0.4M in raspberry polysaccharides and its preparation, can solve problems that have not been studied in depth, and achieve the effects of enhancing phagocytosis, promoting proliferation, and improving immunity
CN112538121AActive Publication Date: 2021-03-23QINGHAI UNIVERSITY

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
QINGHAI UNIVERSITY
Publication Date
2021-03-23

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Abstract

The invention discloses a polysaccharide SM-0.4M which is separated from raspberry polysaccharide. A specific sugar chain structure is identified, and tests prove that the polysaccharide SM-0.4M can promote macrophage proliferation, promote macrophage to release NO and up-regulate expression of TNF-alpha and IL-6, thereby enhancing phagocytic action of macrophage and improving immunity. The anti-tumor effect by themacrophages is facilitated, related products can be prepared, and reference is provided for further exploring the structure-activity relationship of the raspberry polysaccharide anddeveloping polysaccharide anti-tumor drugs and immunologic adjuvants.
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Description

technical field

[0001] The invention belongs to the technical field of natural products, and in particular relates to polysaccharide SM-0.4M in raspberry polysaccharide and its preparation method and application. Background technique

[0002] Plant polysaccharides, also known as plant polysaccharides, are polysaccharides with a degree of polymerization of more than 10 produced by plant cell metabolism. Important biological macromolecules in living organisms are one of the basic substances to maintain the normal operation of life activities.

[0003] At the same time, plant polysaccharides are recognized as natural macromolecules with various biological activities, and most plant polysaccharides have significant immunomodulatory and antitumor activities in vivo. They can not only directly affect the functions of various immune cells such as macrophages, T lymphocytes, B lymphocytes, and natural killer cells, but also regulate the production of related cytokines and complemen...

Claims

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