Folate preparations
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- 阿普罗福尔公司
- Publication Date
- 2021-04-16
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Abstract
Description
technical field
[0001] The present invention relates to reduced folates and their use in the management of eye diseases. Background technique
[0002] Diseases and degenerative conditions of the optic nerve and retina are the leading causes of blindness in the world. Worldwide, approximately 300 million people suffer from various forms of vision impairment caused by these diseases. The most common disorders are optic neuropathy, retinopathy, and glaucoma.
[0003] There are many forms of optic neuropathy. One form is toxic neuropathy, in which damage to the optic nerve is caused by toxic compounds such as methanol. Another form is nutritional neuropathy caused by nutritional deficiencies of one or more micronutrients such as folate and other B vitamins. Current approaches to managing nutritional deficiencies are often based on oral supplements. However, in the case of the eye, this approach may not always be effective because the blood-retinal barrier (BRB) in the retin...