Preparation method of degradable porous ulna middle-end fracture bone connector

Abstract

The invention relates to a preparation method of a customizable, degradable and encircling nano-porous structure material 3D printing bone connector. The preparation method comprises the following steps of designing a reasonable bone connector conforming to the ulna size according to the image data of the ulna middle end obtained by CT scanning, and proportionally mixing a metal nano-mixed material and a hydroxyapatite-polylactic acid compound to obtain a bone connector matrix material; and reloading polylactic acid/osteogenic inducer fibers on the matrix. According to the printed bone connector, a sectional encircling mode is adopted, bone connectors of different lengths can be flexibly arranged according to the fracture situation, and the printed bone connector is suitable for fractures of different degrees; meanwhile, a good stress buffering and protecting effect is achieved on the bone damage position, and the bone cement also has the advantages of being degradable, promoting the formation of bone cells and improving the drug loading performance.

Description

technical field [0001] The invention relates to the technical field of medical devices, in particular to a customizable, degradable, porous bone set. Background technique [0002] Fractures occur from time to time in daily life. Fractures can be caused by trauma or bone diseases. Fractures caused by bone diseases are called pathological fracture The etiology of fractures mainly includes direct violence, indirect violence, cumulative strain, and bone diseases. [0003] At present, the clinical methods for fractures mainly include Kirschner wire fixation, plate fixation, and external fixator fixation to treat fractures. Among them, Kirschner wire fixation is simple and quick in operation, and the trauma is small, but there are situations such as unreliable fixation and easy withdrawal of the needle, which leads to If the fixation fails, a second operation is required to remove it later. Although the plate fixation is relatively firm, it is easy to react with body fluids in th...

AI Technical Summary

Problems solved by technology

[0003] At present, the clinical methods for fractures mainly include Kirschner wire fixation, plate fixation, and external fixator fixation to treat fractures. Among them, Kirschner wire fixation is simple and quick in operation, and the trauma is small, but there are situations such as unreliable fixation and easy withdrawal of the needle, which leads to If the fixation fails, a second operation is required to remove it later. Although the plate fixation is relatively firm, it is easy to react with body fluids in the human body, and the flexibility of the plate and bone pairing is low, and the steel nails used will cause great damage to the original bone. The most important thing is that the steel plate needs to be removed through a second operation, which is likely to cause secondary injury to the patient and damage the restored bone. The external fixation frame is easy to fine-tune and minimally invasive, but wound infection and loosening of the fixation may also occur and damage the peripheral nerves. organize

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