Nucleic acid detection equipment capable of continuously working

A technology for testing equipment and nucleic acids, applied in biochemical equipment and methods, microbe measurement/inspection, biological material sampling methods, etc., can solve the problem of positive substances left in the flow channel system, etc.

Active Publication Date: 2021-04-27
INST OF MICROBIOLOGY - CHINESE ACAD OF SCI +2
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

During the test, if there is a positive sample, it may leave positive substance residues in the flow channel system after the test is completed, and how t...

Method used

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  • Nucleic acid detection equipment capable of continuously working
  • Nucleic acid detection equipment capable of continuously working
  • Nucleic acid detection equipment capable of continuously working

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Embodiment Construction

[0038] For a better understanding of the application, various aspects of the application will be described in more detail with reference to the accompanying drawings. It should be understood that these detailed descriptions are descriptions of exemplary embodiments of the application only, and are not intended to limit the scope of the application in any way. Throughout the specification, the same reference numerals refer to the same elements. The expression "and / or" includes any and all combinations of one or more of the associated listed items.

[0039] It should be noted that in this specification, expressions of first, second, etc. are only used to distinguish one feature from another, and do not represent any limitation on the features. Accordingly, a first body discussed hereinafter may also be referred to as a second body without departing from the teachings of the present application.

[0040] In the drawings, the thickness, size and shape of objects have been slight...

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Abstract

The invention relates to nucleic acid detection equipment capable of continuously working. The nucleic acid detection equipment comprises a nucleic acid amplification reaction module, a fluorescence detection device and a residue removal module, wherein the nucleic acid amplification reaction module comprises a micro-fluidic chip, a to-be-detected sample mixed solution can be injected into a flow channel of the micro-fluidic chip and an amplification reaction chamber, and a nucleic acid amplification reaction is carried out in the amplification reaction chamber; the fluorescence detection device is suitable for detecting a fluorescence signal of the amplification reaction chamber so as to obtain the amount of an amplification product in the amplification reaction chamber in real time according to the fluorescence signal; and the residue removal module comprises a high-temperature fluid cleaning module, and the high-temperature fluid cleaning module is used for injecting fluid with the temperature of 200 DEG C or above into the amplification reaction chamber of the nucleic acid amplification reaction module and the flow channel communicating with the amplification reaction chamber when a detection result of the nucleic acid detection equipment is positive, so that positive residues are removed. According to the nucleic acid detection equipment capable of continuously working, the positive residues in the equipment can be automatically removed, so that false positive of subsequent samples is avoided; and meanwhile, the use cost can be remarkably reduced.

Description

technical field [0001] The invention relates to technical fields such as nucleic acid detection and aerosol detection, and in particular, the invention relates to a continuously working nucleic acid detection device. Background technique [0002] At present, quite a few cases have shown that compared with the SARS epidemic, COVID-19 has a longer incubation period, and people with mild or even asymptomatic infections of COVID-19 may become spreaders of the virus, and fever symptoms of spreaders infected by the virus The relationship to the ability to infect others is neither sufficient nor necessary, exacerbating the difficulty of precisely controlling the spread of the virus. People are eagerly looking forward to a non-contact virus monitoring solution to quickly and accurately identify viruses, provide help for epidemic prevention and control, restore production and living order, and reduce economic and social losses. [0003] Nucleic acid detection is currently the main...

Claims

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Application Information

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IPC IPC(8): C12M1/00C12M1/34C12M1/26
CPCC12Q1/6844C12Q2563/107C12Q2565/629C12Q2545/113
Inventor 陆俊李晶陈科杜昱光王倬张琛李国强赵雪谭广文竺晓山丁玮
Owner INST OF MICROBIOLOGY - CHINESE ACAD OF SCI
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