Method of determining fluid internal pressure in porous soft medium

Abstract

The invention discloses a method for determining the fluid internal pressure in a porous soft medium, which comprises the following steps: judging whether a porous soft medium material to be detected is a single porous soft medium or a porous soft medium surrounded by a wrapping material, and obtaining the mechanical property of the wrapping material and the mechanical property of a porous soft medium frame; exciting shear waves in the to-be-measured porous soft medium, and measuring the shear wave velocity of the shear waves in the to-be-measured porous soft medium; determining elastic deformation of the porous soft medium frame according to a porous elastic mechanical formula; and determining the internal pressure of the to-be-measured porous soft medium according to the deformation of the porous soft medium frame in combination with the obtained mechanical properties of the wrapping material and the obtained mechanical properties of the porous soft medium frame. The method for determining the internal pressure of the fluid in the porous soft medium is nondestructive and noninvasive, can avoid blockage, can track and measure the internal pressure of the fluid in the porous soft medium to be measured for a long time, is simple and quick to operate, can track and measure for a long time, and reduces the cost.

Description

technical field [0001] The invention relates to the technical field of fluid internal pressure measurement in porous soft media, in particular to a method for determining fluid internal pressure in porous soft media. Background technique [0002] Porous media are very common in people's production and life, such as sponges, rocks, soil, plant roots, animal lungs, livers, and tumors. On a microscopic level, there are interconnected pores inside these media that allow fluids (such as water, air, etc.) to flow through them. Measuring the fluid pressure in porous media is of great significance to people's understanding of the mechanical behavior of porous media and the effective use of porous media. [0003] Tumors, especially malignant tumors, seriously threaten people's life and health. Medical research shows that the internal fluid pressure (interstitial fluid pressure, IFP) of most malignant tumors is higher than that of benign tumors and normal physiological tissues. Hig...

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Problems solved by technology

[0005] However, existing micropuncture (micropuncture) technology, needle core (wick in needle) technology, and implanting porous capsules all have defects. The first and third methods are all invasive methods, that is, elements such as probes must be extended. Intrusion into the interior of the material to be tested, which will cause considerable inconvenience, for example, in the monitoring of pressure in tumor treatment, invasive methods will bring great pain and psychological pressure to the subjects, in the design / manufacture / experiment of materials , it means that the integrity of the material is damaged; the second and third methods all have the problem of clogging. When the fine needle and capsule are inserted into the object to be tested, the micro-blocks of the material may block the needle tube and capsule. It is especially serious when the pressure is relatively high; third, the operation is difficult, because the volume of the fine needle and porous capsule is relatively small, the overall operation process is very complicated, and the operator is very demanding; fourth, it is difficult to measure in the body for a long time. When these technologies are actually applied to patient tumors or animal tumors, the tumor must be exposed through surgery. Considering the possibility of bleeding, infection, etc., it is difficult for this type of method to achieve long-term (such as several days, several months) measurement of tumor IFP. Long-term in vivo measurement hinders the evaluation of tumor treatment effect by such methods

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