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Vitamin C and ferrous sulfate sustained and controlled release tablet and preparation method thereof

A technology of ferrous sulfate and vitamins, which is applied in the direction of medical formulas, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc., can solve the problems of drug waste and changes, and achieve low production costs and low costs , the effect of high content

Inactive Publication Date: 2021-06-04
陕西思瑰瑞食品科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Humans cannot synthesize it by themselves and need to ingest it from the outside world. In addition to daily vitamin C intake, oral vitamin C tablets are a good way to supplement vitamin C. However, vitamin C is prone to chemical effects during long-term storage and transportation. Changes, the rapid release of a large amount of vitamin C in the human body will also cause unnecessary waste of drugs

Method used

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  • Vitamin C and ferrous sulfate sustained and controlled release tablet and preparation method thereof
  • Vitamin C and ferrous sulfate sustained and controlled release tablet and preparation method thereof
  • Vitamin C and ferrous sulfate sustained and controlled release tablet and preparation method thereof

Examples

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Embodiment 1

[0032] Vitamin C plus ferrous sulfate sustained and controlled release tablet, which is composed of a tablet-shaped drug core and a sustained-release coating. The tablet-shaped drug core includes the following raw materials in parts by weight: 10 parts of vitamin C, 15 parts of ferrous sulfate, and the balance of water ; The sustained-release coating includes the following raw materials in parts by weight: 20 parts of ethyl cellulose, 5 parts of sodium bicarbonate, 5 parts of toughening agent, 5 parts of anti-blocking agent, 1 part of colorant, 1 part of auxiliary agent, ethanol balance.

[0033] The preparation method of the vitamin C plus ferrous sulfate sustained-release tablet comprises the following steps:

[0034] (1) Take vitamin C in parts by weight and pulverize it into powder, add ferrous sulfate in parts by weight, mix well, add water, keep stirring to make the solution viscous, put it into a tablet kneader, and tablet Kneading of drug cores;

[0035] (2) dissolve...

Embodiment 2

[0038] Vitamin C plus ferrous sulfate sustained and controlled release tablet, which is composed of a tablet core and a sustained release coating. The tablet core includes the following raw materials in parts by weight: 15 parts of vitamin C, 20 parts of ferrous sulfate, and the balance of water ; The sustained-release coating includes the following raw materials in parts by weight: 80 parts of ethyl cellulose, 8 parts of sodium bicarbonate, 15 parts of toughening agent, 10 parts of anti-blocking agent, 5 parts of colorant, 5 parts of auxiliary agent, ethanol balance.

[0039] The preparation method of the vitamin C plus ferrous sulfate sustained-release tablet comprises the following steps:

[0040] (1) Take vitamin C in parts by weight and pulverize it into powder, add ferrous sulfate in parts by weight, mix well, add water, keep stirring to make the solution viscous, put it into a tablet kneader, and tablet Kneading of drug cores;

[0041] (2) dissolve the ethyl cellulose...

Embodiment 3

[0044]Vitamin C plus ferrous sulfate sustained and controlled release tablet, which is composed of a tablet core and a sustained release coating. The tablet core includes the following raw materials in parts by weight: 13 parts of vitamin C, 17 parts of ferrous sulfate, and the balance of water ; The sustained-release coating includes the following raw materials in parts by weight: 50 parts of ethyl cellulose, 6 parts of sodium bicarbonate, 10 parts of toughening agent, 8 parts of anti-blocking agent, 3 parts of colorant, 3 parts of auxiliary agent, ethanol balance.

[0045] The preparation method of the vitamin C plus ferrous sulfate sustained-release tablet comprises the following steps:

[0046] (1) Take vitamin C in parts by weight and pulverize it into powder, add ferrous sulfate in parts by weight, mix well, add water, keep stirring to make the solution viscous, put it into a tablet kneader, and tablet Kneading of drug cores;

[0047] (2) dissolve the ethyl cellulose o...

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Abstract

The invention relates to the technical field of vitamin C sustained release, in particular to a vitamin C and ferrous sulfate sustained and controlled release tablet and a preparation method thereof. The vitamin C and ferrous sulfate sustained and controlled release tablet comprises a tablet-shaped drug core and a sustained-release coating, wherein the tablet-shaped drug core comprises the following raw materials: 10-15 parts of vitamin C, 15-20 parts of ferrous sulfate and the balance of water; the sustained-release coating comprises the following raw materials: 20-80 parts of ethyl cellulose, 5-8 parts of sodium bicarbonate, 5-15 parts of a toughening agent, 5-10 parts of an anti-blocking agent, 1-5 parts of a coloring agent, 1-5 parts of an auxiliary agent and the balance of ethanol. According to the vitamin C and ferrous sulfate sustained and controlled release tablet and the preparation method thereof, vitamin C and ferrous sulfate are combined, vitamin C and ferrous sulfate are added to prepare the sustained release tablet, VC is added while iron is supplemented, ferrous sulfate can be protected from being oxidized, and VC also has the effect of promoting ferrous ion absorption. The vitamin C and ferrous sulfate sustained and controlled release tablet has good toughness and wear resistance, and VC and ferrous ions are uniformly and slowly released through the sustained-release coating, and are released for a long time.

Description

technical field [0001] The invention relates to the technical field of vitamin C sustained release, in particular to a vitamin C plus ferrous sulfate sustained and controlled release tablet and a preparation method thereof. Background technique [0002] Vitamin C is one of the indispensable substances for human beings. It assists various enzyme reactions in the body. Vitamin C plays an important role in the formation of collagen. Collagen is an important substance for the development and repair of human tissue cells, gums, blood vessels, bones, and teeth; it helps the body absorb iron; it accelerates the consumption of vitamin C in a state of tension. Vitamin C participates in the oxidation-reduction process in the body, promotes the growth and development of the human body, enhances the body's resistance to diseases, promotes the formation of collagen in the intercellular substance, maintains the normal functions of teeth, bones, blood vessels and muscles, and enhances the ...

Claims

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Application Information

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IPC IPC(8): A61K9/22A61K9/36A61K47/02A61K47/04A61K47/32A61K47/26A61K47/10A61K47/36A61K47/12A61K47/38A61K47/14A61K31/375A61K33/26A61P3/02
CPCA61K9/2095A61K9/2893A61K9/2813A61K9/282A61K9/2826A61K9/2853A61K9/286A61K9/2866A61K9/284A61K31/375A61K33/26A61P3/02A61K2300/00
Inventor 贾毅
Owner 陕西思瑰瑞食品科技有限公司