Application of traditional chinese medicine for treating psoriasis in preparation of medicine for preventing and treating myocardial ischemia-reperfusion injury

A technology for reperfusion injury and myocardial ischemia, which is used in drug combinations, skin diseases, pharmaceutical formulations, etc., to achieve the effects of relieving pathological changes, inhibiting inflammatory responses, and reducing myocardial ischemia-reperfusion injury

Active Publication Date: 2021-06-18
SOUTHERN MEDICAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

"However, there are no reports of other new uses of the traditional Chinese medicine composition described in the above-mentioned patent application.

Method used

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  • Application of traditional chinese medicine for treating psoriasis in preparation of medicine for preventing and treating myocardial ischemia-reperfusion injury
  • Application of traditional chinese medicine for treating psoriasis in preparation of medicine for preventing and treating myocardial ischemia-reperfusion injury
  • Application of traditional chinese medicine for treating psoriasis in preparation of medicine for preventing and treating myocardial ischemia-reperfusion injury

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Embodiment Construction

[0020] The present invention will be described in further detail below in conjunction with the embodiments and accompanying drawings.

[0021] A. Experimental drug (hereinafter referred to as Psoriasis tablets)

[0022] 1. Raw materials and proportioning: 10 parts by weight of curcuma, 20 parts by weight of sarcocarpus, 20 parts by weight of comfrey, 15 parts by weight of red peony root, 20 parts by weight of Smilax smilax, 20 parts by weight of black plum, 10 parts by weight of licorice, 10 parts by weight of angelica parts by weight, Rhizoma Chuanxiong 10 parts by weight, and Rehmannia 20 parts by weight.

[0023] 2. Preparation method:

[0024] (1) Take Smilax Smilax and pulverize through an 80-mesh sieve to obtain Smilax Smilax powder;

[0025] (2) Weigh curcuma, sarcophagus, comfrey, red peony root, black plum, licorice, angelica, chuanxiong, and raw land dry pieces, decoct and extract three times, add 11 times the amount of water for the first time, and extract for 2 h...

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Abstract

The invention relates to application of a traditional chinese medicine for treating psoriasis in preparation of a medicine for preventing and treating a myocardial ischemia-reperfusion injury. Effective components of the traditional chinese medicine for treating the psoriasis are composed of powder prepared from 20 parts by weight of rhizoma smilacis glabrae, and aqueous extracts of the following raw material medicines of 10 parts by weight of curcuma zedoary, 20 parts by weight of glabrous sarcandra herb, 20 parts by weight of lithospermum, 15 parts by weight of radix paeoniae rubra, 20 parts by weight of dark plum, 10 parts by weight of licorice, 10 parts by weight of chinese angelica, 10 parts by weight of ligusticum wallichii, and 20 parts by weight of unprocessed rehmannia root. The medicine for preventing and treating the myocardial ischemia reperfusion injury can improve a cardiac function of a model rat, inhibit an inflammatory response, regulate an immunity, relieve a pathological change of myocardial fibrosis, and relieve the myocardial ischemia reperfusion injury.

Description

technical field [0001] The invention relates to a pharmaceutical preparation containing an undetermined structure of a traditional Chinese medicine, in particular to a medicine for treating diseases of the cardiovascular system. Background technique [0002] The morbidity and mortality of coronary heart disease and myocardial infarction are increasing year by year. With the development and progress of medical research, various treatment methods such as thrombolysis, percutaneous coronary intervention, and coronary artery stenting have been widely used in clinical treatment. . While restoring myocardial blood supply and reducing myocardial injury through these treatments, ischemia-reperfusion may aggravate cardiac dysfunction and structural damage, and even cause irreversible death of myocardial cells, which is called ischemia-reperfusion injury (Ischemia-reperfusion injury). , MIRI). Therefore, the prevention and treatment of myocardial ischemia-reperfusion injury have als...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P9/10A61P17/06
CPCA61K36/9066A61K36/185A61K36/30A61K36/71A61K36/65A61K36/90A61K36/896A61K36/736A61K36/484A61K36/232A61K36/236A61K36/804A61P9/10A61P17/06A61K2236/331A61K2236/39A61K2236/53A61K2300/00
Inventor 徐洋张月谢庆凤
Owner SOUTHERN MEDICAL UNIVERSITY
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