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Medical application of cycloastrogenol

A technology of cycloastragenol and its use, which is applied in the field of preparation of cycloastragenol to prevent or treat chronic obstructive pulmonary disease drugs, to achieve the effect of increasing body weight, reducing human toxic and side effects, and improving lung function

Pending Publication Date: 2021-07-16
LUNAN PHARMA GROUP CORPORATION
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] But so far, there is no report on the anti-COPD activity of cycloastragenol

Method used

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  • Medical application of cycloastrogenol
  • Medical application of cycloastrogenol
  • Medical application of cycloastrogenol

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Embodiment 1 cycloastragenol injection

[0028]

[0029] Preparation process: mix the prescribed amount of propylene glycol and ethanol evenly, add cycloastragenol, stir to dissolve, add the prescribed amount of 0.9% sodium chloride solution, stir evenly, add 0.5% activated carbon for needles, stir, and decarbonize to obtain the product.

Embodiment 2

[0030] Embodiment 2 cycloastragenol injection

[0031]

[0032] Preparation process: Add cycloastragenol to the prescription amount of PEG-400, stir to dissolve, add 0.9% sodium chloride solution to 10L, stir evenly, add 0.5% activated carbon for needles, stir, decarbonize, and obtain.

Embodiment 3

[0033] Embodiment 3 cycloastragenol injection

[0034]

[0035] Preparation process: Mix the prescribed amount of ethanol and Tween-80 evenly, add cycloastragenol, stir to dissolve, add water for injection to 10L, stir evenly, add 0.5% activated carbon for needles, stir, decarbonize, and obtain.

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Abstract

The invention belongs to the field of medicine, and particularly relates to application of cycloastrogenol, namely application of cycloastrogenol in preparation of medicines for treating chronic obstructive pulmonary disease. Animal tests show that the compound has a remarkable prevention and treatment effect on the chronic obstructive pulmonary disease and can be used for treating the chronic obstructive pulmonary disease at a stable stage or an acute exacerbation stage. The cycloastrogenol is a natural traditional Chinese medicine monomer extracted from the traditional Chinese medicine membranous milkvetch root, is high in safety and low in toxic and side effects, and is suitable for long-term medication treatment of the chronic obstructive pulmonary disease.

Description

technical field [0001] The invention belongs to the field of medicine and relates to the medical use of cycloastragenol, in particular to the use of cycloastragenol in the preparation of drugs for preventing or treating chronic obstructive pulmonary disease. Background technique [0002] Chronic obstructive pulmonary disease (COPD) is a chronic bronchitis and / or emphysema characterized by airflow obstruction, which can further develop into a common chronic disease of pulmonary heart disease and respiratory failure. The disease is related to the abnormal inflammatory response of harmful gases or particles, and the disability rate and mortality rate are very high. The incidence rate of the disease is as high as 9% to 10% in the world over the age of 40. The exact etiology of COPD is unclear. It is generally believed that factors related to the occurrence of chronic bronchitis and obstructive emphysema may cause the onset of COPD. The risk factors that have been discovered can...

Claims

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Application Information

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IPC IPC(8): A61K31/58A61P11/00
CPCA61K31/58A61P11/00
Inventor 姚景春李红华
Owner LUNAN PHARMA GROUP CORPORATION
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