Reagent switching valve for using multiple reagents in same flow channel of micro-fluidic chip
A microfluidic chip, switching valve technology, applied in fluid controllers, laboratory containers, laboratory utensils, etc., can solve the problems of aerosols prone to false positives and laboratory contamination.
Inactive Publication Date: 2021-07-16
四川微康朴澜医疗科技有限责任公司
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Problems solved by technology
For example, in the detection of molecular nucleic acids, whether it is the sample itself or the nucleic acid prepared for detection after preparation, it will pollute the laboratory, and the diffusion of aerosols makes subsequent sample detection prone to false positives
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[0033] The present invention will be further described below with reference to the accompanying drawings and embodiments, and the mode of the present invention includes but not limited to the following embodiments.
[0034] In order to realize the miniaturization, integration and reliability of the standard module assembly of the microfluidic chip, the present invention designs the packaging and integration of the fixed reagent, and the reagent is packaged through the reagent switching valve, so that the chip structure is simple and the flow channel is reduced. The chip volume reduces the impact on the reagents during the chip packaging process. The specific structure is, for example figure 1 As shown: the reagent switching valve 1 includes a switching valve main body 1-1, and the middle part of the switching valve main body 1-1 is provided with a switching valve rotating shaft 1-4, and the switching valve rotating shaft 1-4 is connected to the microchannel by rotation Assembl...
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The invention discloses a reagent switching valve for using multiple reagents in the same flow channel of a micro-fluidic chip. The reagent switching valve comprises a switching valve body, a switching valve rotating shaft is arranged in the middle of the switching valve body, the switching valve rotating shaft is rotationally connected with a micro-channel assembly, the surface of the micro-channel assembly is provided with a first flow channel and a second flow channel which are not communicated. A plurality of drying reagent bins are evenly arranged on one face of the switching valve body in the circumferential direction, and any drying reagent bin can be communicated with the first flow channel and the second flow channel through rotation. A driving connecting device is arranged on the other surface of the switching valve body. By using the valve, integrated packaging of various dry reagents can be facilitated, so that the chip structure is simple, the number of the flow channels is reduced, the size of the chip is reduced, the influence on the reagents in the chip packaging process is reduced, and the production difficulty and cost are reduced.
Description
technical field [0001] The invention belongs to the field of in vitro diagnosis, in particular to a reagent switching valve for using multiple reagents in the same channel of a microfluidic chip. Background technique [0002] Microfluidic technology refers to the technology of manipulating microfluids using tiny channels and various microstructures. It is an emerging interdisciplinary subject involving chemistry, fluid physics, microelectronics, new materials, biology and biomedical engineering. Because of the characteristics of miniaturization and integration, microfluidic devices are usually called microfluidic chips or lab-on-a-chip. A small microfluidic chip is equivalent to sample preparation, reaction, The basic operations such as separation and detection are concentrated and integrated together, and the whole process of analysis can be completed automatically with the instrument. [0003] The application of microfluidic technology in the field of in vitro diagnostics...
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IPC IPC(8): B01L3/00
CPCB01L3/502738B01L3/502715B01L2300/105B01L2400/0622B01L2400/0644
Inventor 唐勇廖政潘颖罗帅
Owner 四川微康朴澜医疗科技有限责任公司