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High-integration-level micro-nano particle convergence micro-fluidic device utilizing oscillatory flow

A microfluidic device, a highly integrated technology, applied in fluid controllers, laboratory containers, laboratory utensils, etc., can solve the limitations of the development and application of micropumps, the output flow field can be adjusted in a small range, and the pump membrane Small deformation and other problems, to achieve the effect of suppressing Brownian motion, wide frequency output range, and short channel

Active Publication Date: 2021-09-03
DALIAN UNIV OF TECH
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the existing designs, the pump membrane of the micropump is mostly made of piezoelectric ceramics or shape memory alloys, which deform under the action of current to change the volume of the pump cavity. The deformation of the pump membrane is small and difficult to control, resulting in an adjustable output flow field. Small range limits the development and application of micropumps

Method used

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  • High-integration-level micro-nano particle convergence micro-fluidic device utilizing oscillatory flow
  • High-integration-level micro-nano particle convergence micro-fluidic device utilizing oscillatory flow
  • High-integration-level micro-nano particle convergence micro-fluidic device utilizing oscillatory flow

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Embodiment Construction

[0026] The specific implementation manners of the present invention will be further described below in conjunction with the accompanying drawings and technical solutions.

[0027] figure 1 Shown is a schematic diagram of a highly integrated micro-nano particle converging microfluidic device using oscillating flow according to the present invention, including a microfluidic chip, a pump membrane control system, a liquid storage tank and a catheter.

[0028] Such as figure 2 As shown, the microfluidic chip includes an inlet and two outlets, and is composed of a valveless micropump and a converging channel 6 . Wherein, the valveless micropump consists of a pump body 4 and a pump membrane 4-2. The pump body 4 mainly includes a micropump inlet, an expansion cone, a pump chamber 4-3, a contraction cone, and a micropump outlet. The micropump inlet serves as a micropump. The inlet 4-1 of the flow control chip is connected to the conduit, and the outlet of the micropump is connected...

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Abstract

The invention belongs to the technical field of micro-fluidic chips, and provides a high-integration micro-nano particle convergence micro-fluidic device utilizing oscillatory flow, which mainly comprises a micro-fluidic chip (comprising a valveless micropump and a convergence channel), a pump membrane control system (comprising an electromagnet and a singlechip), a liquid storage tank and a conduit. The device provided by the invention can realize efficient and convenient micro-nano particle convergence. The micro-fluidic device for converging the micro-nano particles, provided by the invention, is high in integration level, ingenious in design and simple to operate. Oscillatory flow design is utilized to realize 'infinite long channel' flow in a short channel, and a valveless micropump is utilized to drive fluid, so that integration and miniaturization of the device are realized; the elastic lift force and the inertial lift force are combined, convergence and enrichment of the micro-nano particles can be successfully achieved, and the device is used for research in the fields of biology, chemistry and environment.

Description

technical field [0001] The invention belongs to the technical field of biological microfluidic chips, and relates to a microfluidic control device based on oscillating flow that utilizes elastic lift and inertial lift to converge micro-nano particles, specifically a highly integrated micro-nano particle converging microchip using oscillating flow. Fluidic device. Background technique [0002] The study of micro-nano particles (referring to micron-scale and nano-scale particles, hereinafter referred to as particles) is an important content in the fields of biology, medicine, chemistry and the environment, and the aggregation and enrichment of particles is the key link. The birth of microfluidic technology has brought new opportunities for the manipulation of particles. In recent years, a variety of particle manipulation methods based on microfluidic technology have emerged, and the progress of the control methods has promoted the progress of research in related fields. Howev...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B01L3/00
CPCB01L3/50273B01L3/502761B01L2200/0668B01L2200/0636B01L2400/0433B01L2400/0481
Inventor 薛春东赵家铭覃开蓉孙仲平李泳江陈柯洁王宇
Owner DALIAN UNIV OF TECH
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