System for driving micro-fluid magnetic mixing based on micro-wire magnetic field and processing method

A magnetic field-driven, micro-wire technology, applied in the field of magnetron nanometers, can solve problems such as poor control accuracy, and achieve the effect of reducing difficulty, magnetic field strength and magnetic field gradient.

Active Publication Date: 2021-09-07
XI AN JIAOTONG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] However, the current research on the magnetic field to control the movement of magnetic nanoparticles to enhance the mixing between magnetic and non-magnetic solutions still faces the problem of poor control accuracy.

Method used

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  • System for driving micro-fluid magnetic mixing based on micro-wire magnetic field and processing method
  • System for driving micro-fluid magnetic mixing based on micro-wire magnetic field and processing method

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Experimental program
Comparison scheme
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Embodiment Construction

[0036] Embodiments of the present invention are described in further detail below:

[0037] see figure 1 , a kind of microwire drives the movement of magnetic nanoparticles in the microchannel to strengthen the mixing between magnetic solution and nonmagnetic solution. The scheme includes a Y-shaped microfluidic channel, a microwire 1 and a PCB board 5 with a conductive pad 7, By applying current in the microwire 1, it can generate a highly localized magnetic field gradient in space to control the movement of magnetic nanoparticles suspended in the carrier liquid, thereby enhancing the mixing between the magnetic solution and the non-magnetic solution .

[0038] The present invention utilizes the magnetic field of the micro wire to control the movement of the magnetic nanoparticles suspended in the carrier liquid to strengthen the mixing between the magnetic solution and the non-magnetic solution, including a Y-shaped microfluidic channel, a micro wire 1 and a PCB board 5 wit...

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Abstract

The invention discloses a system for driving micro-fluid magnetic mixing based on a micro-wire magnetic field and a processing method. The system comprises a PCB, a silicon substrate is arranged on the PCB, a plurality of micro-wires are deposited on the silicon substrate side by side, the two ends of each micro-wire are connected with a conductive bonding pad arranged on the PCB through conductive connecting pieces, so that connection with an external control circuit and a power supply is realized, the silicon substrate is also provided with a Y-shaped microfluid channel for circulating magnetic nanoparticle suspension liquid and non-magnetic fluid, the bottom surface of the Y-shaped microfluid channel is in direct contact with the micro-wire, and an included angle is formed between the Y-shaped microfluid channel and the micro-wire. The magnetic solution and the non-magnetic solution in the Y-shaped channel are mixed under the action of a micro-wire magnetic field.

Description

technical field [0001] The invention relates to the field of magnetic control nanotechnology, in particular to a system and a processing method for magnetic mixing of magnetic nano particle suspension and non-magnetic solution in a microchannel driven by a microwire magnetic field. Background technique [0002] Since the microfluidic system can integrate sample sampling, dilution, mixing, reaction, separation, detection and other processes on a small chip, it is widely used in the biomedical field, such as the detection of blood components, single cell Control, isothermal PCR amplification, cancer detection, etc. In the multi-step operation of the microfluidic system, sufficient mixing and contact between the sample to be detected and the marker is the key link to improve the accuracy of sample detection, but in the traditional microfluidic system, due to the low Reynolds of the microfluidic channel Therefore, how to improve the mixing efficiency between different solutions...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B01L3/00B01F13/08B82Y40/00
CPCB01L3/5027B82Y40/00
Inventor 孙佳佳李明佳史宗谦钟明杰陈双刘小凤
Owner XI AN JIAOTONG UNIV
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