Photoacoustic imaging device and method based on white light interference

Abstract

The invention discloses a photoacoustic imaging device and method based on white light interference. The device comprises an optical interference detection system, a photoacoustic excitation system, a scanning system and a computer, wherein one end of the optical interference detection system is electrically connected with the computer, and the other end of the optical interference detection system is optically connected with the scanning system; one end of the photoacoustic excitation system is electrically connected with the computer, and the other end of the photoacoustic excitation system is optically connected with the scanning system; and the scanning system is optically connected with the sample. According to the photoacoustic imaging method based on white light interference, the change of the reflected light intensity of the photoacoustic signal excitation point in the sample is detected through white light interference, photoacoustic signals from different depths of the sample at the same time can be obtained, certain depth resolution capacity is achieved, signal demodulation is conducted through Fourier transform, and compared with a currently adopted time domain demodulation mode, the detection sensitivity can be effectively improved.

Description

technical field [0001] The invention belongs to the technical field of photoacoustic imaging, and in particular relates to a photoacoustic imaging device and method based on white light interference. Background technique [0002] Photoacoustic imaging (PAI) is a medical imaging technology that has developed rapidly in recent years. PAI combines the high contrast of pure optical imaging with the deep penetration of pure ultrasound imaging. It is a non-invasive imaging mode that can be used for Structural and functional imaging of biological tissues. The principle of PAI is the photoacoustic effect. When the pulsed laser irradiates the biological tissue, the tissue absorbs the light energy and produces thermoelastic expansion, which generates the corresponding ultrasonic wave. The absorption distribution image of the tissue can be obtained by detecting the ultrasonic wave. [0003] At present, contact photoacoustic imaging technology based on piezoelectric transducers is wide...

AI Technical Summary

Problems solved by technology

Although this method solves the problem of the water layer and improves the flexibility of the method, there are still defects in this method, that is, the depth information inside the sample is blurred at the same time, and it is impossible to obtain the excitation position of the photoacoustic signal in the sample. Depth information, and the demodulation results are overly dependent on the manufacturing accuracy of the 3×3 fiber coupler, otherwise large errors will occur

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