Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Method for constructing temporomandibular joint osteoarthritis animal model by applying digital technology

A technology for temporomandibular joint and osteoarthritis, which is applied in the field of applying digital technology to construct an animal model of temporomandibular joint osteoarthritis, can solve the problems of poor accuracy, poor expected controllability, poor intuitiveness, etc., and achieves a simple production process, Avoid heterogeneity, high precision effects

Inactive Publication Date: 2021-09-28
JIAMUSI UNIVERSITY
View PDF4 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The object of the present invention is to provide a method for constructing an animal model of temporomandibular joint osteoarthritis using digital technology, so as to solve the problem that most of the above-mentioned background technologies do not use digital technology such as 3D scanning, which has poor intuitiveness and poor accuracy. The expected controllability is poor, resulting in the problem of model sample heterogeneity

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Method for constructing temporomandibular joint osteoarthritis animal model by applying digital technology
  • Method for constructing temporomandibular joint osteoarthritis animal model by applying digital technology

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0021] as attached figure 1 , 2 Shown:

[0022] 1. Experimental animals, material software and instruments:

[0023] 30 SD rats weighing 160-180g were provided by the Animal Experiment Center of Jiamusi University and kept in a clean environment;

[0024] 10% chloral hydrate, 1ml syringe, crown scissors, stereo microscope, 0.9% normal saline, small straight forceps, six-hole plate, hematoxylin;

[0025] The CAD software is Sirona inlab, the brand of the 3D metal printer is Concept LASER, the model is MLAB, and the model design software is AutotFab MLab.

[0026] 2. Experimental method;

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a method for constructing a temporomandibular joint osteoarthritis animal model by applying a digital technology, relates to the technical field of medicine and animal models, and solves the problem that an existing animal model construction method is poor in intuition, poor in precision and poor in expected controllability, resulting in that a model sample is easy to generate heterogeneity. The method for constructing the temporomandibular joint osteoarthritis animal model by applying the digital technology comprises the steps of: selecting an SD rat, anesthetizing, and digitally scanning animal teeth; selecting a 6-week-old female SD rat with the weight of 160-180 g, feeding the rat in a clean environment, adaptively feeding the rat for one week, injecting 10% chloral hydrate into the abdominal cavity of the SD rat, and anesthetizing the rat; producing a telescopic crown; establishing the temporomandibular joint osteoarthritis animal model; and under the anesthesia of chloral hydrate, adhering by zinc phosphate cement. The method applies the digital technology, is simple in production process, more visual in 3D scanning and high in precision, has predictability, and avoids heterogeneity of samples.

Description

technical field [0001] The invention relates to the technical field of medicine and animal models, in particular to a method for constructing an animal model of temporomandibular joint osteoarthritis by using digital technology. Background technique [0002] Temporomandibular joint is one of the most common sites of osteoarthritis, and it is also one of the severe manifestations of temporomandibular joint disorder. The occurrence of temporomandibular joint osteoarthritis is mostly attributed to the change of biomechanical factors of temporomandibular joint, and abnormal occlusion is considered to be the potential pathological factor of temporomandibular joint osteoarthritis. Temporomandibular joint osteoarthritis is the main cause of temporomandibular joint pain and dysfunction. The main pathological change is persistent inflammation. The establishment of mandibular joint bone animal models will help us to study mandibular osteoarthritis in more depth. [0003] For example,...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61B34/10
CPCA61B34/10A61B2034/105
Inventor 周立波刘鹏慧吴凡赵雨晴周大凤
Owner JIAMUSI UNIVERSITY
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com