Biosensor capable of obtaining broadband enhanced terahertz absorption spectrum and test method

Abstract

The invention discloses a biosensor capable of obtaining a broadband enhanced terahertz absorption spectrum. The biosensor comprises a terahertz wave refraction lens and a sub-wavelength metal sensing structure; the terahertz wave refraction lens is hemispheroid-shaped; the sub-wavelength metal sensing structure is a metal plate, and a plurality of grids are uniformly distributed on the metal plate; the circular tangent plane of the terahertz wave refraction lens is arranged opposite to the grating of the sub-wavelength metal sensing structure, and a to-be-measured gap is formed between the terahertz wave refraction lens and the sub-wavelength metal sensing structure. According to the biosensor, the sub-wavelength metal sensing structure and the hemispherical cylindrical lens are innovatively combined, and a certain tiny gap is formed; incident terahertz waves are utilized to efficiently excite the resonance effect of surface plasmon elements on the sensing structure, and an electromagnetic enhancement effect is utilized to realize enhanced terahertz absorption spectrum detection of a trace sample, and therefore, the biosensor has an important application value on unmarked sensing detection of biomolecules.

Description

technical field [0001] The invention belongs to the technical field of biosensing, and in particular relates to a biosensor capable of obtaining a broadband enhanced terahertz absorption spectrum and a testing method. Background technique [0002] Terahertz (THz) waves refer to electromagnetic waves with a frequency of 0.1THz-10THz and a wavelength of 0.03mm-3mm, and its spectrum is between infrared and microwave. Different from traditional spectral analysis techniques such as infrared spectroscopy and X-rays, the skeleton vibration and rotation spectra of many bio-organic molecules such as proteins, DNA, RNA, amino acids, sugars, etc., and the energy levels of weak interaction forces between molecules are in the terahertz band. This makes terahertz spectroscopy have inherent advantages and important applications in the study of biomolecules. [0003] Surface plasmons are highly localized surface waves on metal surfaces, which are very sensitive to the dielectric environmen...

AI Technical Summary

Problems solved by technology

[0004] At present, most of the biosensors based on surface plasmons are used in the optical band, and there are very few in the terahertz band, and they are all used for refractive index sensing, which cannot realize broadband absorption spectrum detection and analysis of samples.

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