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Application of traditional Chinese medicine composition and/or pharmaceutical preparation containing traditional Chinese medicine composition in preparation of anti-inflammatory drugs or immunomodulatory drugs

A technology of pharmaceutical preparations and compositions, which is applied in the field of traditional Chinese medicine, can solve problems such as drug marketing, and achieve the effects of treating abnormal immune function, prolonging life, and regulating the body's immunity

Active Publication Date: 2021-10-15
BEIJING CHINESE MEDICINE HOSPITAL AFFILIATED CAPITAL MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are no related drugs on the market

Method used

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  • Application of traditional Chinese medicine composition and/or pharmaceutical preparation containing traditional Chinese medicine composition in preparation of anti-inflammatory drugs or immunomodulatory drugs
  • Application of traditional Chinese medicine composition and/or pharmaceutical preparation containing traditional Chinese medicine composition in preparation of anti-inflammatory drugs or immunomodulatory drugs
  • Application of traditional Chinese medicine composition and/or pharmaceutical preparation containing traditional Chinese medicine composition in preparation of anti-inflammatory drugs or immunomodulatory drugs

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0071] This example provides a traditional Chinese medicine composition, including 9g of raw ephedra, 30g of raw gypsum, 10g of Bupleurum, 15g of baicalensis, 15g of Artemisia annua, 10g of bran fried herb, 30g of verbena, 15g of patchouli and 10g of raw licorice.

[0072] The present embodiment also provides a pharmaceutical preparation comprising the above-mentioned traditional Chinese medicine composition, and its preparation method is as follows: take Artemisia annua, bran fried herb and patchouli according to the prescription weight of the traditional Chinese medicine composition, add 10 times the amount of water, and steam distillation Extract the volatile oil for 2 hours, collect the volatile oil, and set aside; collect the distilled water in another device, set aside; take raw ephedra, raw gypsum, Bupleurum bupleurum, scutellaria baicalensis, verbena and raw licorice according to the prescription, add water and decoct three times, add 10 for the first time Double the am...

Embodiment 2

[0074]This example provides a traditional Chinese medicine composition, including 7g of raw ephedra, 33g of raw gypsum, 8g of Bupleurum, 13g of Scutellaria baicalensis, 13g of Artemisia annua, 13g of Atractylodes atractylodes, 33g of verbena, 13g of Huoxiang and 8g of licorice.

[0075] This embodiment also provides a pharmaceutical preparation comprising the above-mentioned traditional Chinese medicine composition, and its preparation method is as follows: take Artemisia annua, Atractylodes Rhizoma Atractylodis and Huoxiang according to the prescription weight of the traditional Chinese medicine composition, add 5 times the amount of water, and extract the volatile oil by steam distillation. The extraction time is 1 hour, collect the volatile oil, and set aside; the distilled water liquid is collected in another device, set aside; according to the prescription, take raw ephedra, raw gypsum, Bupleurum, scutellaria, verbena and licorice, add water and decoct three times, add 20 t...

Embodiment 3

[0077] This example provides a traditional Chinese medicine composition, including raw ephedra 12g, raw gypsum 28g, Bupleurum 13g, baicalin 18g, Artemisia annua 18g, atractylodes 8g, verbena 28g, Huoxiang 15g and licorice 13g.

[0078] This embodiment also provides a pharmaceutical preparation comprising the above-mentioned traditional Chinese medicine composition. The preparation method is as follows: take Artemisia annua, Atractylodes Rhizoma Atractylodis and Huoxiang according to the prescription weight of the traditional Chinese medicine composition, add 20 times the amount of water, and extract the volatile oil by steam distillation. The extraction time is 3 hours, collect the volatile oil, and set aside; the distilled water liquid is collected in another device, set aside; take raw ephedra, raw gypsum, Bupleurum bupleurum, scutellaria baicalensis, verbena and licorice according to the prescription, add water and decoct twice, add 3 Double the amount of water, decoct for 0...

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Abstract

The invention relates to the field of traditional Chinese medicines, and particularly provides application of a traditional Chinese medicine composition and / or a pharmaceutical preparation containing the traditional Chinese medicine composition in preparation of inflammation drugs or immunomodulatory drugs, and the traditional Chinese medicine composition is obtained by repeatedly optimizing the composition and content of compound traditional Chinese medicines through clinical research and fundamental research. In the formula, ephedra, gypsum and radix bupleuri are combined as monarch drugs; radix scutellariae, herba artemisiae annuae and rhizoma atractylodis are used as ministerial drugs; verbena and agastache rugosus are used as adjuvant drugs; and liquorice is a conductant drug of the formula. The medicines have the effects of clearing away heat and toxic materials, freeing lung and relieving asthma, and play a positive role in regulating the body immunity, particularly regulating the abnormal number of immune cells, enabling the number of the immune cells to be normal, and regulating the unbalance of proinflammatory factors and anti-inflammatory factors; the proinflammatory factors and the anti-inflammatory factors are recovered to be in a balanced state, and immune dysfunction and diseases caused by the immune dysfunction are prevented and / or treated.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to the application of a traditional Chinese medicine composition and / or a pharmaceutical preparation containing the traditional Chinese medicine composition in the preparation of anti-inflammatory drugs or immunomodulatory drugs. Background technique [0002] The body's immune system plays an important role in clearing cancerous tissues and pathogenic bacteria invasion, and cellular immunity is an important part of the body's immune system. In cellular immunity, lymphoid T cells and lymphoid B cells occupy a central position, and lymphoid T cells are mainly divided into CD8 and CD8 according to their surface markers. + Cytotoxic T cells, CD4 + helper T cells, CD4 + CD25 + regulatory T cells, etc. According to different surface markers, lymphoid B cells are mainly divided into CD45RB cells, B1 cells, B2 cells, etc. Lymphatic T cells and lymphoid B cells express a varie...

Claims

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Application Information

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IPC IPC(8): A61K36/85A61P29/00A61P37/02A61K33/06
CPCA61K36/17A61K33/06A61K36/233A61K36/539A61K36/282A61K36/284A61K36/85A61K36/532A61K36/484A61P29/00A61P37/02A61K2236/331A61K2236/39A61K2236/51A61K2236/333A61K2300/00
Inventor 郭玉红崔煦然刘清泉
Owner BEIJING CHINESE MEDICINE HOSPITAL AFFILIATED CAPITAL MEDICAL UNIV
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