Application of traditional Chinese medicine composition and/or pharmaceutical preparation containing traditional Chinese medicine composition in preparation of anti-inflammatory drugs or immunomodulatory drugs

A technology of pharmaceutical preparations and compositions, which is applied in the field of traditional Chinese medicine, can solve problems such as drug marketing, and achieve the effects of treating abnormal immune function, prolonging life, and regulating the body's immunity

Active Publication Date: 2021-10-15

BEIJING CHINESE MEDICINE HOSPITAL AFFILIATED CAPITAL MEDICAL UNIV

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AI-Extracted Technical Summary

Problems solved by technology

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Method used

[0160] At the phylum level, compared with the normal control group, the abundance ratios of Firmicutes and Bacteroides in the model control group were significantly reduced. According to literature reports, Firmicutes and Bacteroidetes are closely related to obesity. There are more Firmicutes in the intestine than Bacteroidetes, which leads to the body absorbing calories more efficiently and gaining weight easily. After the mice in the model control group were infected with th...

Abstract

The invention relates to the field of traditional Chinese medicines, and particularly provides application of a traditional Chinese medicine composition and/or a pharmaceutical preparation containing the traditional Chinese medicine composition in preparation of inflammation drugs or immunomodulatory drugs, and the traditional Chinese medicine composition is obtained by repeatedly optimizing the composition and content of compound traditional Chinese medicines through clinical research and fundamental research. In the formula, ephedra, gypsum and radix bupleuri are combined as monarch drugs; radix scutellariae, herba artemisiae annuae and rhizoma atractylodis are used as ministerial drugs; verbena and agastache rugosus are used as adjuvant drugs; and liquorice is a conductant drug of the formula. The medicines have the effects of clearing away heat and toxic materials, freeing lung and relieving asthma, and play a positive role in regulating the body immunity, particularly regulating the abnormal number of immune cells, enabling the number of the immune cells to be normal, and regulating the unbalance of proinflammatory factors and anti-inflammatory factors; the proinflammatory factors and the anti-inflammatory factors are recovered to be in a balanced state, and immune dysfunction and diseases caused by the immune dysfunction are prevented and/or treated.

Application Domain

AntipyreticAnalgesics +5

Technology Topic

ChemistryAsthma +25

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Examples

Experimental program(6)

Example Embodiment

[0070] Example 1

[0071] This embodiment provides a Chinese medicine composition, including 9g, raw blue gypsum 30g, Chaihu 10g, Astragalus 15g, Artemisia 15g, bran, bran, 30g, patchouli, 15g, and glycycetic 10g.

[0072] The present embodiment also provides a pharmaceutical preparation including the above-described Chinese medicine composition. The formulation is as follows: Artemisia, bran atractylodes and patchouli, plus 10 times water, add 10 times water, vapor distillation Extract volatile oil to extract for 2 h, collect volatile oil, standby; the different water liquid after distillation is collected, spare; qi yellowing, raw gland, Bupleurum, Astragalus, chest whitening, Chaihu, Huaudus, Masterwood and glycyclasses and add water three times, first add 10 Double water, decoction 1H, second, three times each plus 8 times water, each decoction 0.5h, combined with the boiling liquid, filtered, the filtrate combined with the above-described distillation, concentrated to relative density 1.20-1.25 (50 ° C) of the thick paste, dry, powdered, addextrin, forming a particle semi-finished product, dry, sprayed into the distillation collected volatile oil, mixing, i.e., the pulmonary detoxification particles 30g.

Example Embodiment

[0073] Example 2

[0074]This embodiment provides a Chinese medicine composition, including 7 g of Zenghuang, 33G, Chaihu 8g, Astragalus 13g, Artemisia 13g, Atractylodes 13g, Vr. 33g, musk 13g and licorice 8g.

[0075] This embodiment also provides a pharmaceutical preparation comprising the above-described Chinese medicine composition, and the method is as follows: Artemisia, Atractylodes and Muxiang, add 5 times water, add 5 times water, and extract volatile oil with water vapor distillation. The extraction time is 1 h, collects volatile oil, standby; the dried water liquid is collected, spare; according to the quantity of Ma Yong, raw gypsum, Bupleurum, Astragalus, chest and licorice plus water, first add 20 times Water, decoction of 5h, second, three times each additional water, each decoction 0.5h, combined with the boiling liquid, filtered, the filtrate combined with the above-described distillation, concentrated to relative density of 1.20 -1.25 (50 ° C), dry, powdered, pellets, dry, dry, sprayed into the distillation collected volatile oil, mixed, i.e., the pulmonary detoxification particles, dry tablets, and form a tablet.

Example Embodiment

[0076] Example 3

[0077] This embodiment provides a Chinese medicine composition, including Zhenhuang 12g, raw gypsum 28g, Bupleurum 13g, Astragalus 18g, Artemisia 18g, Atractylodes 8g, Verbench 28g, musk 15g and licorice 13g.

[0078] The present embodiment also provides a pharmaceutical preparation including the above-described Chinese medicine composition. The formulation is as follows: Artemisia, Atractylodes, and musk, add 20 times water, add 20 times water, and extract volatile oil with water vapor distillation. The extraction time is 3 h, collecting volatile oil, spare; the dried water liquid can be collected, spare; in accordance with the quantity of Ma Yong, raw gypsum, Bupleurum, Astragalus, chest and licorice plus water, first add 3 Double water, decoction of 0.5 h, 2 additional water, decoction 3H, combined with the boiling liquid, filtered, the filtrate combined with the above-described distillation, concentrated to relative density of 1.20- 1.25 (50 ° C) of the thick paste, dry, powder, a particle semi-finished product, dry, sprayed into the distillation collected volatile oil, mixed, i.e., the pulmonary detoxification particles, in the capsule, and form a capsule.

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Application of traditional Chinese medicine composition and/or pharmaceutical preparation containing traditional Chinese medicine composition in preparation of anti-inflammatory drugs or immunomodulatory drugs

A technology of pharmaceutical preparations and compositions, which is applied in the field of traditional Chinese medicine, can solve problems such as drug marketing, and achieve the effects of treating abnormal immune function, prolonging life, and regulating the body's immunity

AI-Extracted Technical Summary

Problems solved by technology

Method used

Abstract

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Examples

Example Embodiment

Example Embodiment

Example Embodiment

PUM

Description & Claims & Application Information

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