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Composition for treating beriberi and onychomycosis and preparation method thereof

A technology for onychomycosis and a composition is applied in the field of a composition for treating athlete's foot onychomycosis and its preparation field, and can solve the problems of poor curative effect and inability to cure onychomycosis in the treatment of onychomycosis

Inactive Publication Date: 2021-11-02
陈守海
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But above-mentioned method all can not radical cure to the treatment of onychomycosis, curative effect is not good.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0040] The present invention also provides a method for preparing a composition for treating beriberi and onychomycosis, comprising the following steps: combining Notopterygium, Woody Fragrance, Polygala, Safflower, Atractylodes Rhizome, Chuanxiong, Codonopsis, Cuscuta, Duhuo, Angelica, Ginseng, Gastrodia elata, and Guoshan After the dragon, Spatholobus and Centella asiatica are crushed, the mixture is obtained, and ethanol is added to the mixture, soaked for 30-90 minutes, filtered and separated after ultrasonication, and the primary filtrate and primary filter residue are obtained; ethanol is added to the primary filter residue, filtered and separated after ultrasonication , to obtain the secondary filtrate; the primary filtrate and the secondary filtrate are combined to obtain the combined filtrate, and after the combined filtrate is rotary evaporated, vacuum drying is carried out to obtain the extract; after the extract is broken, it is mixed with grape seed oil and sweet al...

Embodiment 1

[0050] A preparation method for a composition for treating beriberi onychomycosis, comprising the steps of:

[0051] Raw materials: Notopterygium 5kg, Woody Fragrance 5kg, Polygala 5kg, Safflower 7kg, Atractylodes macrocephala 7kg, Rhizoma Chuanxiong 7kg, Codonopsis 2kg, Cuscuta 2kg, Duhuo 2kg, Angelica 2kg, Ginseng 1kg, Gastrodia elata 1kg, Mountain Dragon 2kg, Caulis Spatholobus 1kg, Centella asiatica 1kg, grape seed oil 0.2kg, sweet almond oil 0.2kg and ginger root oil 0.2kg.

[0052] After crushing Notopterygium, Woody Fragrance, Polygala, Safflower, Atractylodes macrocephala, Rhizoma Chuanxiong, Codonopsis, Cuscuta, Duhuo, Angelica, Ginseng, Gastrodia elata, Mountain Dragon, Mildew Spatholobus and Centella asiatica, the mixture was added with a volume concentration of Soak in 55% ethanol for 30min, and after ultrasonic power is 200w, ultrasonic frequency is 35KHz, and temperature is 45°C, after ultrasonication for 30min, filter and separate to obtain primary filtrate and ...

Embodiment 2

[0057] A preparation method for a composition for treating beriberi onychomycosis, comprising the steps of:

[0058] Raw materials: Notopterygium 7kg, Woody Fragrance 7kg, Polygala 7kg, Safflower 10kg, Atractylodes macrocephala 10kg, Rhizoma Chuanxiong 10kg, Codonopsis 4kg, Cuscuta 5kg, Duhuo 5kg, Angelica 5kg, Ginseng 3kg, Gastrodia elata 3kg, Spatholobus 5kg, Caulis Spatholobus 3kg, Centella asiatica 3kg, grape seed oil 0.6kg, sweet almond oil 0.6kg and ginger root oil 0.6kg.

[0059] After crushing Notopterygium, Woody Fragrance, Polygala, Safflower, Atractylodes macrocephala, Rhizoma Chuanxiong, Codonopsis, Cuscuta, Duhuo, Angelica, Ginseng, Gastrodia elata, Mountain Dragon, Mildew Spatholobus and Centella asiatica, the mixture was added with a volume concentration of Soak in 70% ethanol for 60 minutes, after ultrasonic power is 250w, ultrasonic frequency is 40KHz, temperature is 55 ℃ under the condition of ultrasonic 40min, filter and separate, obtain primary filtrate and...

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Abstract

The invention provides a composition for treating beriberi and onychomycosis and a preparation method thereof, which relate to the technical field of traditional Chinese medicines. The composition for treating beriberi and onychomycosis comprises the following raw materials: notopterygium root, elecampane, polygala tenuifolia, safflower, bighead atractylodes rhizome, ligusticum wallichii, codonopsis pilosula, semen cuscutae, radix angelicae pubescentis, angelica sinensis, ginseng, gastrodia elata, vernonia gratifolia, caulis spatholobi, centella asiatica, grape seed oil, sweet almond oil and ginger root oil. Based on the principle of clearing heat and eliminating dampness, nourishing blood and moistening dryness, dredging meridians and dredging collaterals, through research by the inventor, notopterygium root, safflower, bighead atractylodes rhizome and radix angelicae pubescentis are used as monarch drugs, elecampane, polygala tenuifolia, ligusticum wallichii, codonopsis pilosula, semen cuscutae, angelica sinensis, ginseng, gastrodia elata, vernonia gratifolia, ginger root oil, caulis spatholobi and centella asiatica are used as auxiliary materials, the effects of removing dampness, diminishing swelling, activating blood to promote menstruation, eliminating dampness, inducing diuresis and activating blood to promote menstruation can be achieved on foot focuses, and grape seed oil and sweet almond oil have the moisturizing and synergistic effects.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a composition for treating beriberi fungus and a preparation method thereof. Background technique [0002] As we all know, beriberi is the most common superficial fungal disease in ringworm. According to the main clinical manifestations, it can be divided into vesicular and scaly type, impregnation and erosion type, and hyperkeratosis type. Peeling, impregnation, and erosion will occur between the toes, or There are many blisters, which are more common in patients who like to wear airtight shoes. If left untreated, it can cause infections in other parts, such as tinea manuum, onychomycosis, and jock itch. This disease can be treated with oral medicine or topical medicine. About 1 to 2 months, generally can be cured, but easy to relapse. [0003] Onychomycosis is a (finger, toe) nail disease caused by fungal infection. , Gray or white and other colors, area...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8988A61K36/9068A61K9/00A61K47/12A61K47/44A61P17/00A61P31/02A61P31/10
CPCA61K36/237A61K36/285A61K36/69A61K36/286A61K36/284A61K36/236A61K36/344A61K36/39A61K36/43A61K36/232A61K36/258A61K36/8988A61K36/87A61K36/486A61K36/23A61K36/73A61K36/9068A61K9/0014A61K47/44A61K47/12A61P17/00A61P31/10A61P31/02A61K2236/333A61K2236/39A61K2236/53A61K2236/51A61K2300/00
Inventor 陈守海
Owner 陈守海
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