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Shortfall quantity liquid container

A liquid container and container technology, applied in the direction of biochemical instruments, bioreactor/fermenter combination, specific-purpose bioreactor/fermenter, etc., can solve the problems of increasing consumption and cost, and achieve high sterility and consumption Low, the effect of reducing the risk of contamination

Pending Publication Date: 2021-11-09
SARTORIUS STEDIM BIOTECH GMBH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the transfer of liquid media from such liquid containers to closed systems sometimes requires multiple applications of sterile connectors, sterile filters or the like, which in turn increases effort and costs

Method used

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  • Shortfall quantity liquid container
  • Shortfall quantity liquid container
  • Shortfall quantity liquid container

Examples

Experimental program
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Embodiment Construction

[0035] Figures 1 to 6 The volume reduction liquid container 1 according to the proposed solution shown in the various embodiments is used for outputting a liquid medium, here a biological medium, which is prefilled on the manufacturer's side, to a bioprocessing plant, in particular a bioreactor In the device, the bioprocessing equipment or the bioreactor forms a closed system or is integrated into a closed system. The bioreactor not shown here for the sake of clarity is designed, for example, as a laboratory bioreactor, i.e. as a bioreactor which, in contrast to a production bioreactor, has a relatively small volume of up to 10 liters. Working volume (maximum usable filling volume). Such bioreactors are used to carry out biotechnological processes, which are here and preferably used for the production of pharmaceutical agents (ATMPs) for novel therapies. For example a biotechnological process can also be a cell expansion process for T cells. In any event, a biological reac...

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Abstract

The invention relates to a shortfall quantity liquid container for dispensing a liquid, in particular biological, medium into a bioprocess technology installation, in particular into a bioreactor, wherein the liquid container (1) provides a receiving volume (2) for the liquid medium, wherein the liquid container (1) has two dimensionally stable container parts (6, 7), which are movable relative to one another between a starting position and an end position, and has an outlet connector (8) for conducting out the liquid medium. It is proposed that the liquid container (1) has a delimiting means (9) which delimits the receiving volume (2) at least in certain portions and which is variable in shape and which is connected to the dimensionally stable container parts (6, 7) such that a relative movement, which causes a change in volume of the receiving volume (2), of the dimensionally stable container parts (6, 7) relative to one another is associated with a change in shape of the delimiting means (9).

Description

technical field [0001] The invention relates to an abatement liquid container according to the preamble of claim 1 for the discharge of a liquid medium into a bioprocessing plant, in particular into a bioreactor, a liquid according to claim 13 The described packaging assembly with a packaging and such a liquid container which is aseptically packed in the packaging as well as the use of such an aseptically packed liquid container and / or such a packaging assembly according to claim 14 . Background technique [0002] A bioprocessing plant is here understood in a very general sense to mean a device with which a biotechnological process can be carried out or supported. By way of example only bioreactors are mentioned here in which microorganisms or tissue cells are cultured under predetermined conditions. Such devices usually have a container in which a biological reaction medium is contained, on the one hand, substances provided for biotechnological processes, such as microorga...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12M1/12C12M1/00C12M1/26
CPCC12M23/06C12M23/26C12M23/28C12M23/34C12M33/04C12M37/04C12M35/04
Inventor B·德本纳M·多伊斯
Owner SARTORIUS STEDIM BIOTECH GMBH
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