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Micro-fluidic chip

A technology of microfluidic chips and coverslips, which is applied in the direction of laboratory appliances, laboratory containers, chemical instruments and methods, etc., can solve the problems of liquid sample leakage, different reaction time, and limited reaction time, so as to reduce the reaction time Time, increased reaction time, increased adequacy effects

Active Publication Date: 2021-11-12
BEIJING MICVIC BIOTECH CO LTD
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Problems solved by technology

[0003] The current microfluidic chip generally adopts the method of bonding the cover sheet and the substrate to form the corresponding flow area and reaction area, which requires extremely high sealing technology. Once the bonding sealing effect is not good, the liquid sample will leak. At the same time, the microfluidic chip involves the detection of different disease markers. According to the detection needs of different samples, different reaction times may be required, and the existing microfluidic chip is due to its inherent structural characteristics. The reaction time is limited, which has the problem of narrow detection range when detecting certain disease markers

Method used

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Embodiment Construction

[0025] It should be noted that, in the case of no conflict, the embodiments of the present invention and the features in the embodiments can be combined with each other.

[0026] In describing the present invention, it should be understood that the terms "center", "longitudinal", "transverse", "upper", "lower", "front", "rear", "left", "right", " The orientations or positional relationships indicated by "vertical", "horizontal", "top", "bottom", "inner" and "outer" are based on the orientations or positional relationships shown in the drawings, and are only for the convenience of describing the present invention and Simplified descriptions, rather than indicating or implying that the device or element referred to must have a particular orientation, be constructed and operate in a particular orientation, and thus should not be construed as limiting the invention. In addition, the terms "first", "second", etc. are used for descriptive purposes only, and should not be understood ...

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Abstract

The invention proposes a micro-fluidic chip, and the chip comprises a micro-channel defined by a substrate and a cover plate; sample fluid is injected into the micro-channel through a sample adding hole, the height of the top wall of the micro-channel is lower than that of the contact face of the substrate and the cover plate, and the sample fluid flows towards an outlet of the micro-channel under the capillary acting force of the micro-channel. Through the above setting, the liquid leakage on the side face of the micro-channel can be effectively prevented, the detection result is more accurate, and the invalid detection rate and the rejection rate are reduced.

Description

technical field [0001] The invention relates to the technical field of in vitro diagnosis, in particular to a microfluidic chip. Background technique [0002] The microfluidic chip is the main platform for the realization of microfluidic technology, which can integrate the basic operation units such as sample preparation, reaction, separation, and detection in the process of biological, chemical, and medical analysis into a small chip. The entire analysis process is automatically completed through the microchannel to realize various functions of conventional chemical or biological laboratories. Microfluidic chips have the advantages of light size, small amount of samples and reagents used, fast reaction speed, a large number of parallel processing, and ready-to-use and disposable. They have great potential in the fields of biology, chemistry, and medicine. In recent years, they have developed It has become a new research field interdisciplinary of biology, chemistry, medici...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B01L3/00
CPCB01L3/5027B01L2200/025B01L3/50273B01L2200/027B01L2300/0816B01L2400/0406B01L2300/0887
Inventor 李松晶韩军叶涛唐奎
Owner BEIJING MICVIC BIOTECH CO LTD
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