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Cosmetic soothing and repairing test method and application thereof

A testing method and cosmetic technology, applied in the direction of measuring devices, instruments, scientific instruments, etc., can solve the problems of long time, inaccurate test results of soothing and repairing effects, cumbersome testing process, etc., achieving fast detection speed, eliminating subjective factors, The effect of improving the detection range

Inactive Publication Date: 2021-11-26
广州美域医学检验有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Due to the inaccurate test results for the soothing and repairing effect of cosmetics, the test process is cumbersome and takes a long time

Method used

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  • Cosmetic soothing and repairing test method and application thereof
  • Cosmetic soothing and repairing test method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Embodiment 1: adopt the mixed solution of mass fraction 10% (mass ratio SDS: capsaicin: lactic acid=5:3.5:1.5) to carry out patch on experimenter's arm inner side 1.5 * 1.5cm skin area, each spot tester titration 0.08mL mixed solution, tear off the patch after 24h, and detect the moisture content of the test skin after tearing off the patch for 24h ( CM 825 skin moisture probe), number of erythema ( MX 18 skin pigment probe) and transepidermal water loss (AquaFlux AF200 skin water loss tester); after that, apply the sample to be tested and press (2.0±0.1) mg / cm 2 The dosage is applied once, and the moisture content of the skin, the number of erythema and the transepidermal water loss are tested 2 hours after the application, and the soothing and repairing effect of the sample to be tested is judged.

Embodiment 2

[0035] Embodiment 2: adopt the mixed solution of mass fraction 8% (mass ratio SDS: capsaicin: lactic acid=6:2:2) to carry out patch on experimenter's arm inner side 1.5 * 1.5cm skin area, each spot tester titration 0.08mL mixed solution, tear off the patch after 28h, and test the moisture content of the skin, the number of erythema and the transepidermal water loss 24h after tearing off the patch; after that, apply the sample to be tested, and press (2.0±0.1) mg / cm 2 The amount of the product is applied in a single application, and the moisture content of the skin, the number of erythema and the transepidermal water loss are tested after 2 hours, 4 hours and 8 hours of application respectively, and the soothing and repairing effect of the sample to be tested is judged.

Embodiment 3

[0036] Embodiment 3: adopt the mixed solution of mass fraction 12% (mass ratio SDS: capsaicin: lactic acid=4:5:1) to carry out patch on experimenter's arm inner side 1.5 * 1.5cm skin area, each spot tester titration 0.08mL mixed solution, tear off the patch after 20h, and test the moisture content of the skin, the number of erythema and the transepidermal water loss after tearing off the patch 24h; then apply the sample to be tested, press (2.0±0.1)mg / cm 2 The amount of the product is applied in a single application, and the moisture content of the skin, the number of erythema and the transepidermal water loss are tested after 2 hours, 4 hours and 8 hours of application respectively, and the soothing and repairing effect of the sample to be tested is judged.

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PUM

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Abstract

The invention provides a cosmetic soothing and repairing test method and application thereof, and the cosmetic soothing and repairing test method comprises the following steps: (1) performing spot pasting on human hand skin by using a stimulation solution to obtain a skin stimulation model, and detecting characterization parameters; (2) smearing a to-be-detected sample on the skin stimulation model obtained in the step (1), then detecting skin characterization parameters, and evaluating the soothing and repairing effects of the to-be-detected sample, wherein the solute of the stimulation solution in the step (1) comprises a combination of at least two of SDS, capsaicin or lactic acid. The testing method provided by the invention can effectively, scientifically and accurately detect the soothing and repairing effects of the cosmetics, and the detection speed is high.

Description

technical field [0001] The invention belongs to the field of cosmetic efficacy testing, and in particular relates to a cosmetic soothing and repairing test method and its application, in particular to an accurate cosmetic soothing and repairing testing method and its application. Background technique [0002] At present, there is no unified standard for soothing and repairing test methods. In the existing methods, patients with skin problems usually use the test substance continuously for at least 28 days to evaluate the effect of the product. The detection speed is slow, and due to the skin Different properties lead to differences in test results. [0003] CN110018161A discloses a method for detecting the anti-irritation properties of anti-irritant products, comprising step 1) acquiring images of skin or skin mimics after patch treatment, wherein the patch is coated with a substance containing the anti-irritant product and an irritant The gel composition of the object; ste...

Claims

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Application Information

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IPC IPC(8): G01N33/00
CPCG01N33/00G01N33/0078
Inventor 孙云起裴运林莫洁梅陈杰郭朝万胡露
Owner 广州美域医学检验有限公司
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