63 results about "Skin stimulation" patented technology

The present invention relates to a method for producing a canine atopic dermatitis animal model, a canine atopic dermatitis animal model produced thereby, and a use thereof. According to the present invention, a canine atopic dermatitis animal model is produced by skin stimulation on a dog through epicutaneous sensitization with ovalbumin at a concentration of 1 to 5 mg / ml once daily for 1 to 2 weeks and then with ovalbumin at a concentration of 1 to 5 mg / ml once daily for 2 to 8 weeks. The resulting animal model exhibits clinical symptoms of atopic dermatitis, changes in relevant factors such as increased expression levels of IgE and CCL17, and elevated expression levels of Th2-related cytokines IL-4, IL-31, and IL-13. Therefore, this invention enables the establishment of a standardized animal model for symptoms and Th2 immune responses appearing upon the onset of atopic dermatitis, and the model can be used in clinical studies for screening candidate agents for the prevention, alleviation, or treatment of atopic dermatitis.

A skin-stimulating device for imparting a stimulus to the skin, includes: a first film that bends when a voltage is applied; a plurality of first film-form electrodes provided on one surface of the first film so as to be separated from one another by a prescribed spacing; a second film that bends when a voltage is applied; a second film-form electrode provided on one surface of the second film; and a dielectric member molded from a dielectric rubber in the shape of a thin sheet in which a hole is opened, with other surface of the first film being affixed to a first surface that is a prescribed surface of the dielectric member, and the other surface of the second film being affixed to a second surface on the reverse side from the first surface.

The invention relates to the technical field of visual impaired people assistance, in particular to a self-adaptive perception prompting system and method for visual impaired people assistance, and the method comprises the following steps: obtaining environment data around a user; the target information is recognized and transmitted to the user through the wearable somatosensory feedback module in a skin stimulation mode, so that the user can perceive surrounding objects and directions thereof through skin stimulation, and then obstacle avoidance can be achieved. Furthermore, an active exploration self-adaptive auxiliary module is introduced, an action track of a user is collected and analyzed to be compared with an environment model, an omission area or space deviation in perception is recognized, and a reinforcing prompt is triggered, so that the user is guided to complete more comprehensive environment exploration and space construction. Limitations of a traditional blind guiding stick and a traditional blind guiding dog are avoided, and higher-precision space perception and navigation assistance can be obtained only by wearing the somatosensory feedback module.

1. Name of the product in this design: Transcutaneous acupoint electrical stimulator (ear acupoint). 2. Purpose of this design: To stimulate acupoints on the ear through the skin to prevent and treat diseases. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: 3D view 1.

1. Name of the product in this design: Beauty Device. 2. Purpose of this design: It is a beauty device that can stimulate the skin through an electrically conductive part protruding from the bottom surface. 3. The key design features of this product are its overall shape. 4. The picture or photo that best illustrates the key design points: Design 1 3D diagram 1. 5. Design 1 is designated as the basic design.

The invention discloses a plaster for gout as well as a preparation method and application thereof, belongs to the technical field of medicines, and aims to solve the problems of poor moisture retention in winter, low transdermal efficiency and strong sensitive skin irritation of the existing external plaster for gout. The plaster comprises the following raw materials: a first component (10-20 parts of indigo naturalis, 20-30 parts of rhubarb and other 10 traditional Chinese medicines) and a second component (0.5-1 part of sea buckthorn fruit polysaccharide, 0.5-1 part of cynomorium songaricum polysaccharide, 2-3 parts of evening primrose oil microcapsules and the like). The preparation method comprises the steps of raw material pretreatment (extraction and crushing), component mixing and plaster forming. The first component ensures the core curative effects of clearing heat, eliminating dampness and activating meridians to stop pain, the second component synergistically solves the problems of skin dryness and transdermal penetration in winter, the modified component ensures the stability, the sensitive skin irritation rate is low, and the traditional Chinese medicine composition is suitable for patients suffering from gouty swelling and pain and skin sensitivity in winter and wide in clinical applicability.

The female polyurethane condom comprises a condom body, a bottom elastic ring body is fixed to the bottom end of the condom body, an upper elastic ring body is arranged on the top of the interior of the condom body, and the diameter of the upper elastic ring body is smaller than that of the bottom elastic ring body; a plurality of annular protruding parts are formed on the inner side wall of the middle of the condom body. The polyurethane condom is made of polyurethane, the condom body with the thin wall face can be manufactured, the annular protruding part of the polyurethane condom can promote the touch feeling of the male genital organ and the outer wall face of the male genital organ after the male genital organ enters the condom, skin irritation is improved, and the using effect is improved.

The present invention relates to a smart diaper having an improved structure, which minimizes skin problems of a wearer, increases an electrical connection force with a detection line of the diaper when a sensing device is mounted on the diaper, and minimizes a foreign body sensation or discomfort of the wearer when the sensing device is mounted on the diaper.

The invention relates to application of extracellular vesicles in antibacterial yoga clothes, the application comprises that the extracellular vesicles are micro-fixed on the surface layer of yoga clothes fabric through a padding method or a spraying method, and the problems that chemical antibacterial agents (silver ions, graphene and the like) of existing yoga clothes are high in cost and large in skin irritation, and environment / health risks exist are solved. The extracellular vesicles are slightly fixed on the surface layer of the yoga clothes fabric through a padding method or a spraying method, and the extracellular vesicles can inhibit biological membranes formed by pathogenic bacteria such as staphylococcus aureus and escherichia coli on the surface layer of the yoga clothes fabric by interfering pathogenic bacteria quorum sensing. The fabric has the advantages that peculiar smell substances such as sulfides and fatty acid volatile substances generated by metabolism of bacteria in a sweat wet environment are reduced from the source, fabric peculiar smell control is achieved, compared with chemical antibacterial agents such as silver ions and graphene, biotoxicity risks and environmental accumulation hidden dangers are avoided, anaphylactic reactions caused by long-term contact between yoga clothes and skin can be remarkably reduced, and wearing safety is improved.

The present invention relates to a skin-stimulating patch capable of autonomously contracting, and more particularly, to a skin-stimulating patch comprising a contractile material and a trigger material. According to one embodiment of the present invention, it is possible to provide a patch for skin stimulation, which is a patch capable of stimulating skin, and which comprises: a contractile material that can contract under a preset condition; and the triggering material is used for applying preset energy to the contractile material so that the condition can be met.

1. Name of the product in this design: Skin Beauty Device. 2. Purpose of this design: It is a beauty device that can stimulate the skin through an electrically conductive part protruding from the bottom surface. 3. The key design features of this product are its overall shape. 4. The image or photograph that best illustrates the design's key points: a 3D model.

The present invention relates to a beauty device. The beauty device identifies information regarding a cartridge that contains a cosmetic product and is inserted into the device, so as to automatically provide various skin-stimulation functions.

Compositions, systems, and methods for reducing electrical induction and / or skin irritation caused by application of an alternating electric field to the skin of a subject are disclosed. The compositions, systems, and methods involve administering to a subject at least one composition comprising at least one local anesthetic, and then applying an alternating electric field to the subject.

1. The name of the design product: transdermal acupoint electrical stimulation instrument. 2. The use of the design product: for stimulating acupoints of the head through the skin to achieve the purpose of preventing and treating diseases. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view 1.

The special danger warning device for the deaf based on skin stimulation, using a microphone, receives warnings and vital sounds and sends them to a microcontroller with Bluetooth and Wi-Fi for differentiation and classification. After comparing the received data with the information defined in the claimed invention, the microcontroller sends a signal to activate the vibration motor, and the vibration motor creates a vibration on the skin and informs the deaf person. In situations where there is a possibility of a change in the body's vital signs, the claimed invention has the ability to detect and issue an alert by generating vibrations on the skin and also to the claimed invention application via Bluetooth. In situations such as gassing that causes an increase in the amount of carbon monoxide gas, it has the ability to detect the amount of gas and generate an alert by inducing vibrations on the skin. Considering the safety challenges of the deaf, including the risk of getting lost and the inability to get help from others, and other disorders such as sleepwalking, the claimed invention is capable of monitoring the individual and sending the real-time location to the application via Bluetooth.

1. The name of the design product: ear stimulator. 2. The use of the design product: is a accessory of transdermal acupoint electrical stimulation instrument, used for stimulating ear acupoint through the skin, to achieve the purpose of preventing and treating diseases. 3. The design points of the design product: in shape. 4. The picture or photo that best shows the design points: design 1 perspective view 1. 5. Design 1 is designated as the basic design.

A skin stimulation device that applies mechanical stimulation to skin, has an actuator element having an electroded body, and a first electrode and a second electrode provided to the electroded body, which is displaced in accordance with a drive voltage applied to the first electrode and the second electrode, and a film-like base material that is wearable to the skin, which is provided with the actuator element and is stretchable and contractible, and an element array in which a plurality of the actuator elements are connected in a column along a surface of the base material is formed.

The invention discloses an adhesion-drug release collaborative design system and method of adhesion type hydrogel, which are applied to the field of biomedical materials. A gradient cross-linking density and dynamic dual-network synergistic adhesion mechanism, a pH responsive nanopore channel of a drug sustained-release layer and a molecularly imprinted chain segment synergistic controlled-release mechanism, and a micro-breathable structure of a bionic cuticle barrier membrane and a zwitter-ion anti-adhesion surface synergistic protection mechanism are constructed; collaborative optimization of triple properties of adhesion self-enhancement in a wet environment, intelligent drug release and low skin irritation is realized; the method does not depend on traditional single function layer stacking or static parameter regulation and control, and starts from three dimensions of material microstructure design, interface coupling relation construction and dynamic response mechanism implantation to establish a set of multi-level collaborative design process capable of being implemented in an engineering mode. The finally formed hydrogel application product can maintain stable adhesive force in a complex physiological environment, at the same time releases treatment components as required, and reduces interference to a skin barrier function to the maximum extent.

The present disclosure provides a slit blade block and an electric razor capable of more efficiently shaving body hair while suppressing stimulation to skin. The slit blade block according to the present disclosure includes a slit outer blade having a plurality of outer blade pieces extending in a first direction and spaced apart from each other along a second direction intersecting the first direction. The slit blade block further includes a comb component comprising a plurality of combs that are disposed outside the slit outer blade in the first direction and spaced apart from each other along the second direction. The comb component comprises a protrusion protruding outward in the first direction, and the protrusion includes a first protrusion extending across two or more of combs disposed side by side in the second direction.

1. The name of the design product: transdermal acupoint electrical stimulation instrument (cranium ear). 2. The use of the design product: for stimulating ear acupoints through the skin to achieve the purpose of preventing and treating diseases. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view 1.

The invention provides a construction method of an atopic dermatitis animal model, and the construction method comprises the step of carrying out sensitization treatment on a TSLP transgenic mouse by adopting local skin stimulation and a mixed sensitization source so as to construct the atopic dermatitis animal model. In the technical scheme, the TSLP transgenic mouse is induced and sensitized by adopting local skin stimulation and a mixed sensitization source, and the skin of the mouse specifically expresses the TSLP, so that the skin inflammation can quickly appear and is similar to the human AD symptom. Compared with a common mouse-induced allergy animal model, the method has the advantages of high sensitization efficiency, obvious sensitization effect and the like, can be applied to experimental research on AD diseases, and provides a research model for clinical research on AD diseases.

The present disclosure provides a dermal stimulation device and methods of use thereof. The dermal stimulation device comprises a removable head piece and an elongate base member. The elongate base member comprises a proximal portion comprising one or more conducting surfaces, a circumferential rim configured for engaging with the removable head piece, and an actuatable element configured to actuate one or more electrical components housed within the elongate handle. The removable head piece comprises a plurality of light emitting elements and a distal flange configured for engaging with the circumferential rim of the elongate base member, wherein engaging elongate base member with the removable head piece causes the elongate base member to be in electrical communication with the removable head piece.

Embodiments of the present invention provide a cosmetic applicator apparatus for a cosmetic eye applicator. The cosmetic applicator apparatus comprising a shell and at least one stimulation element configured to stimulate the skin. A liquid outlet channel runs through the shell, connecting to the bottle body. At the shell's output end, there are two distinct surfaces: an application surface and a stimulation surface, positioned on opposite sides. The application surface and the stimulation surface are oriented at intersecting angles, with the liquid outlet located on the application surface, and the stimulation component is placed near the stimulation surface. This structural arrangement ensures that the functions of liquid application and skin stimulation remain independent, preventing interference between the two.

The invention relates to modified chitosan oligosaccharide, a composite decontamination preparation and a preparation method thereof, and belongs to the technical field of nuclide decontamination and daily chemicals. The raw materials mainly comprise AESA, OP-10, K12A, APG1214, LAO-30, modified chitosan oligosaccharide and the like. The modified chitosan oligosaccharide is carboxymethyl chitosan oligosaccharide, the water solubility is improved after modification, and tests show that the material has a good function of removing radionuclides from human skin. According to the compound decontamination preparation, actinide nuclide decontamination and cobalt and cesium decontamination efficiency verification proves that the decontamination efficiencies in 6-hour and 12-hour experimental groups respectively reach 85% and 65% or above. Skin stimulation experiments of the decontamination liquid prove that the decontamination liquid has no stimulation or damage to normal skin of a human body. A skin sensitization test proves that the guinea pig skin sensitization reaction grade is 0. The invention is mainly applied to emergency decontamination of radionuclide.

A skin stimulation brush pin includes an elongated tubular body, a base bottom member, an electrode member, and a metal shaft. The elongated tubular body has a proximal end portion. The tubular body includes a radially contracted portion on a distal end side of the tubular body. The base bottom member is made of a metal to allow conduction of electricity from an electric circuit. The base bottom member is at the proximal end portion of the elongated tubular body. The electrode member is connected to an opening of the tubular body on the distal end side thereof and has an exposed distal end, the radially contracted portion of the tubular body radially protruding toward the electrode member. The metal shaft is in a tubular inner portion of the tubular body to couple the base bottom member and the electrode member.

To provide a cosmetic device in which an applicator for applying cosmetics and generating skin stimulation such as electric current or vibration is integrally formed with the cosmetic device, eliminating the need for bringing and assembling a separate tool and enabling the application of cosmetics and skin stimulation to be performed simultaneously with only one device. [Solution] The cosmetic device (10) of the present invention includes a container (200) for storing cosmetics and an applicator (110) for applying the cosmetics to the skin, which are integrally provided, and a cap (100) for opening and closing the container. When at least a portion of a tip (120) formed at one end of the applicator and at least a portion of the cap come into contact with the skin, at least one of an electric current and a vibration can be transmitted to the contacted skin through the tip without a separate power switch.

This disclosure relates to a method, device, and system used for identifying and treating responders to external nerve stimulation via a combination of a skin electrode assembly and a functional near-infrared spectroscopy (fNIRS) device. More specifically, this specification discloses a method for cutaneous stimulation of the trigeminal nerve, occipital nerve, vagus nerve, facial nerve and / or any of their branches, and a method for measuring cerebral blood flow in a target brain region.

1. The name of the design product: ear stimulator. 2. The use of the design product: is a accessory of transdermal acupoint electrical stimulation instrument, used for stimulating ear acupoint through the skin, to achieve the purpose of preventing and treating diseases. 3. The design points of the design product: in shape. 4. The picture or photo that best shows the design points: design 1 perspective view 1. 5. Design 1 is designated as the basic design.

The present invention relates to a skin care device having a wire power transmission structure. A driving force generation unit for moving a skin stimulus generation unit in a handpiece may be mounted on a control body, and a driving force is transmitted to a wire body through a wire, thereby reducing the weight of the handpiece for skin treatment. Noise or vibration due to driving may not be generated in the handpiece for skin treatment, thereby significantly improving an operator's convenience and treatment satisfaction during the treatment. The handpiece for skin treatment has a simplified structure, and can be designed without limitations on the size and shape thereof, thereby significantly enhancing the degree of freedom in handpiece design.

This utility model discloses a massage top rod with rollers and a massage mechanism. The massage top rod includes a top rod body and rollers. The bottom end of the top rod body is placed inside the massage mechanism housing, and the other end has an arc-shaped mounting groove. The roller is rotatably mounted via a rotating shaft, with one end inside the groove and the other end extending out of the groove as a massage end. The massage mechanism includes a drive mechanism, a transmission mechanism, a swing mechanism, and massage components. The transmission mechanism drives the long rotating shaft to rotate, which in turn causes the swing massage head to cooperate with the massage top rod to achieve a kneading action. This utility model's massage top rod transforms fixed friction into rolling friction during massage, reducing skin irritation and improving comfort. The rollers roll without power, simulating human hand massage techniques, enhancing the massage effect, and requiring no additional power source, thus reducing the failure rate. Using a massage top rod with rollers in the massage mechanism can effectively improve the massage effect and comfort, enhancing market competitiveness.