Biological tissue personalized blood perfusion rate evaluation method and system

A technology of biological tissue and evaluation system, applied in blood flow measurement, medical science, diagnosis, etc., can solve problems such as not considering individualized blood flow conditions, and achieve the effect of precise control of boundary temperature

Active Publication Date: 2022-06-24
MAGI CO LTD
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Problems solved by technology

The existing multimodal ablation surgery planning model does not consider the individualized blood flow, which is quite different from the actual situation

Method used

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  • Biological tissue personalized blood perfusion rate evaluation method and system
  • Biological tissue personalized blood perfusion rate evaluation method and system
  • Biological tissue personalized blood perfusion rate evaluation method and system

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Embodiment Construction

[0046] In the following description, numerous technical details are set forth in order to provide the reader with a better understanding of the present application. However, those of ordinary skill in the art can understand that even without these technical details and various changes and modifications based on the following embodiments, the technical solutions claimed in the present application can be realized.

[0047] Explanation of some concepts:

[0048] The blood flow condition refers to the richness of blood vessels at the ablation site, the blood flow velocity, etc. The blood flow condition may include: blood perfusion rate, blood convection coefficient, and the like.

[0049] Multimodal ablation, including a cryoablation stage and a subsequent heating ablation stage, wherein cryoablation methods include but are not limited to liquid nitrogen ablation, argon helium ablation and low temperature alcohol ablation, and heating ablation methods include but are not limited t...

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Abstract

This application relates to the field of biomedical engineering, and discloses a method and system for evaluating the individualized blood perfusion rate of biological tissues. Based on the influence of peripheral blood flow on the thawing process of the target biological tissue after freezing, the calculation of local tissue is established by the principle of boundary convection heat transfer. An algorithm for personalized blood perfusion rate, the method includes: obtaining the surface area of ​​the ice ball formed by freezing the target biological tissue; obtaining the temperature gradient of the ice ball surface and its change over time according to the temperature of the ice ball surface The gradient and its variation with time and the surface area of ​​the ice ball determine the personalized blood perfusion rate around the target biological tissue; output the personalized blood perfusion rate around the target biological tissue.

Description

technical field [0001] The present application relates to the field of biomedical engineering, in particular to the field of data processing technology combining medical technology and computer technology. Background technique [0002] In recent years, physical ablation of target biological tissues such as tumors, as a minimally invasive ablation method, has been widely used in the treatment of benign and malignant tumors such as liver, lung, and kidney. Common physical ablation methods include cryoablation and thermal ablation. [0003] Specifically, multimodal ablation therapy combines cryoablation and heating ablation, and utilizes the huge thermal stress generated by rapid temperature changes inside the tumor to completely destroy tumor cells, release tumor antigens, and activate the body's specific immune response to tumors. in various solid tumors. Based on a variety of animal models of highly metastatic tumors and a large number of experimental results, its effect h...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B5/026A61B5/01
CPCA61B5/026A61B5/015
Inventor 王逸飞张康伟张爱丽徐学敏孙建奇
Owner MAGI CO LTD
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