33 results about "Peripheral blood flow" patented technology

The present invention relates to a novel non-invasive perfusion / resistance status monitor system and methods of using the same, and more specifically, a vascular perfusion status monitor system receiving and processing signals from at least two pulse oximeter probes, where each of the at least two pulse oximeter probes are situated at advantageously different locations in a patient. Novel pulse oximeter probes are configured to be placed, respectively, across the lip or cheek, across the septum or nares of the nose, and on the tongue. These probes are fabricated to provide signals to estimate arterial oxygen saturation. Conventional oximeter probes also can be configured to function according to the novel methods of determining differences in peripheral blood flow and / or resistance described herein.

The invention relates to methods, apparatus, articles-of-manufacture, and coded data signals for measuring cardiac output, limb blood flow, perfusion, blood pressure, artery elasticity, and cardiovascular deterioration and disease, including performing these measurements on a continuous heart beat-by-beat basis, for humans and animals. Unlike empirical methods of other noninvasive blood pressure concepts, the invention is grounded on scientifically appropriate hemodynamic principles that studies have validated as accurate, and is practical for wide clinical use. Devices constructed in accordance with the invention can be comfortably employed for numerous applications, including hospital monitoring, physician's office cardiovascular disease management and drug therapy monitoring, home monitoring, and athletic applications.The invention may be implemented in a variety of single or multi-sensor embodiments, such as: invasive pressure cannula sensor systems; non invasive pressure transducer arrays and piezo or other strain sensing materials that are placed against the skin above arteries; “upstream” pulsing-sensors (that apply single or multi-frequency vibrations that are measured “downstream” from the first placement location); other types of plethysmographic sensors; sonic / ultrasonic / Doppler sensors; MRI blood spin magnetizer / sensors; oxygen sensors; and electrocardiographic sensors, etc.

In a system and method for peripheral impedance plethysmography, an electrode for application to the patient's limb includes two outer current electrodes and two inner voltage electrodes. A distance between the two inner electrodes is automatically input into an analyzing device, either as a pre-stored value or as determined automatically from the electrode. Peripheral blood flow is calculated in accordance with that distance.

An apparatus and method process magnetic resonance image (MRI) data and other data from a subject, including image data corresponding to at least one of angiographic data, four-dimensional blood flow, neurological blood flow, abdominal blood flow, and peripheral blood flow in the subject, and applies a compressed sensing (CS) reconstruction method utilizing a complex difference of the image data as a sparsifying transform for imaging of at least one of blood flow and magnetic resonance angiography to output a reconstructed image of the blood flow and magnetic resonance angiography, in the subject with increased processing speed and having high accuracy. The apparatus receives the MRI data of the fluid flow from an MRI device. The processor operates predetermined software, receives the MRI data, and applies the CS reconstruction method to generate the reconstructed image. An output device outputs the reconstructed image of the fluid flow.

The present invention provides systems and methods for treating wounds in patients who lack the innate ability to regulate glucose (e.g., diabetic patients). In one aspect of the invention, a method includes positioning an internal bypass device within the duodenum to inhibit contact between chyme passing therethrough and an internal wall of the duodenum and maintaining the internal bypass device within the duodenum for a sufficient period of time to decrease insulin resistance and reduce a blood glucose level in the patient. The internal bypass device increases peripheral blood flow and elevates an immune system response to accelerate healing of the wound.

The present invention provides a composition containing an extract from Wisteria floribunda, Myristica fragrans, Punica granatum, Trapa bispinosa or a derivative thereof, Coix lachiryma-jobi, Elfvingia applanata and Ganoderma lucidum or a derivative thereof (optionally further containing Panax ginseng or Panax japonicus), which has a superior antiviral activity, a superior peripheral blood flow-improving activity and a superior hair growth-stimulating activity, and a production method thereof.

Methods and compositions are described which are useful for increasing the peripheral blood flow in mammals during conditions of hemodilution. The methods and compositions involve the use of materials to increase the blood viscosity in the system of microscopic blood vessels.

A non-invasive detection system with a peripheral vascular blood flow adjusting function comprises a data collecting module, a filtering module, a feature point / section identification module, a data analysis module and a blood flow adjusting function evaluation module. Cuff downstream front arm or hand skin blood flow volume signals are continuously measured before and after blood flow of the brachial artery is blocked by means of the method that the unilateral upper arm is pressurized through a cuff, after the blood flow volume signals are subjected to filtering treatment, a stable blood flow section before compression of the cuff and a congestion section after relieving of cuff compression are identified, and the specific value of average blood flow volumes of the congestion section and the stable blood flow section is calculated to obtain the index of quantitative evaluation for the peripheral vascular blood flow adjusting function. The non-invasive effect is achieved in the whole operating process, the measuring time is short, through feature analysis for a time registration curve of the blood flow, a blood flow changing section dominated by peripheral vascular ischemic reaction is identified, the influence of the upstream artery endothelial function on peripheral blood flow signals can be effectively excluded to achieve targeted evaluation on the human body peripheral vascular blood flow adjusting function, and the pretty good application prospects are achieved.

For medicine, sports and cosmonautics, a method of biomechanotherapy massage and therapeutic action on a human body performed both by heat and light waves and by mechanical waves which are sequential and parallel combinations of longitudinal and transverse modulated solitary waves of length from 0.005 to 0.1 m propagating along the body with speed from 0.01 to 12 m / s, where the solitary waves are formed on the body due to an impulsive action of separate thermovibratodes interconnected with a controlled link and acting on a human body with a temperature from 0 to 90° C., a specific pressure from 0.5·105 to 4·105 Pa and a shear thrust from 0.1 to 100 N. The proposed method of biomechanotherapy allows to increase efficiency of the therapeutic and sports massage and to improve results of an integral treatment of various diseases. Wave biomechanotherapy increases 1.5–2 times the peripheral blood flow facilitating the work of the cardiovascular system, improving the rheological properties of blood, blood supply to all organs and the functional condition of these parameters. Wave biomechanotherapy actively stimulates the metabolism, accelerates rehabilitation processes in organs and tissues and increases drainage of decay products from a body in a natural way.

An electrical therapy device for a heart has a hemodynamic sensor (1), an electrostimulation device (2) and a control unit (30). The hemodynamic sensor (1) is adapted to detect a peripheral blood flow. In this arrangement, the control unit (30) has a tachyarrhythmia evaluation device (3) and a telemetry receiver (6). The control unit (30) controls the electrostimulation device (2) for stimulating and defibrillating the heart in dependence on the peripheral blood flow which is detected by the hemodynamic sensor (1). In addition a tachyarrhythmia and / or the peripheral hemodynamic effects thereof is detected, wherein the peripheral hemodynamic effects of the tachyarrhythmia are determined on the basis of the peripheral blood flow which is detected by a peripheral hemodynamic sensor (1). The results of detecting a tachyarrhythmia and / or the peripheral hemodynamic effects thereof can be used to defibrillate or stimulate the heart by means of the electrostimulation device (2).

An instrument for synchronously obtaining and analyzing the electronystagmograph associated with dizziness and the ear-peripheral blood flow signal is composed of light-shielding eye mask, micro light source, CCD sensor, raster, infrared light source, infrared detector, signal acquisition card, computer, display and printer.

An apparatus and method process magnetic resonance image (MRI) data and other data from a subject, including image data corresponding to at least one of angiographic data, four-dimensional blood flow, neurological blood flow, abdominal blood flow, and peripheral blood flow in the subject, and applies a compressed sensing (CS) reconstruction method utilizing a complex difference of the image data as a sparsifying transform for imaging of at least one of blood flow and magnetic resonance angiography to output a reconstructed image of the blood flow and magnetic resonance angiography, in the subject with increased processing speed and having high accuracy. The apparatus receives the MRI data of the fluid flow from an MRI device. The processor operates predetermined software, receives the MRI data, and applies the CS reconstruction method to generate the reconstructed image. An output device outputs the reconstructed image of the fluid flow.

The present invention provides a composition that can effectively improve peripheral blood flow to thereby ameliorate cold sensation, numbness, pains and other skin symptoms, as well as frostbites, chilblains and chaps and other skin disorders associated with disturbed peripheral blood flow. This composition has no side effects. Specifically, the peripheral blood flow-improving composition contains, as an active ingredient, a extract of a plant of the genus Lepidium of the family Cruciferae. More specifically, the composition contains as an active ingredient a extract of maca plant (Lepidium meyenii Walp). Food and beverage products, perfumes and cosmetics, and pharmaceutical products containing the peripheral blood flow-improving composition are also provided.

The invention relates to the field of medical instruments, and particularly discloses a blood pump favorable for forming physiological laminar flow. The blood pump comprises a sleeve, a rotor arrangedin the sleeve and a driving device arranged outside the sleeve and used for driving the rotor to rotate; the rotor comprises a rotor cylinder which is coaxial with the sleeve and rotor blades fixed on the inner wall of the rotor cylinder; a hollow blood flow channel is formed in the middle of the rotor; a drainage channel is arranged in the sleeve, is positioned on the rear side of the rotor, gradually narrows along the blood flow direction and is used for draining the peripheral blood flow to the middle blood flow. Blood flowing out of the drainage channel can recover to a normal laminar flow state, and the possibility of blood component damage and thrombus generation in the subsequent flowing process is reduced effectively.

The invention discloses a medicament for curing central serous chorioretinopathy (CSCR) and a preparation method thereof. The medicament is prepared from the materials in parts by weight as follows: 10g to 30g of Tuckahoe, 10g to 20g of rhizoma alismatis, 10g to 30g of salvia miltiorrhiza, 10g to 15g of shizandra berry, 5g to 20g of rhizoma cyperi, 5g to 20g of radix curcumae, 10g to 20g of radix achyranthis bidentatae, 10g to 15g of feather cockscomb seed, 10g to 15g of cicada ecdysis, 10g to 15g of horsetail, 10g to 20g of boxthorn fruit and 5g to 15g of liquorice. The method for preparing the medicament comprises the following steps: grinding the components into fine powder; decocting the components for twice; filtering; concentrating into thick paste; drying; grinding into fine powder; and packaging into capsules. By integrating the components as a whole, the medicament has the effects of activating blood, relieving depression, inducing dieresis and improving vision, thereby dilating the blood vessel, reducing the vascular resistance, increasing the peripheral blood flow, improving the microcirculation, reducing the capillary permeability, improving the metabolism of tissues, promoting the absorption of pathological changes and improving the visual function. The method has high curative effect on clinical application.

The present invention provides a composition that can effectively improve peripheral blood flow to thereby ameliorate cold sensation, numbness, pains and other skin symptoms, as well as frostbites, chilblains and chaps and other skin disorders associated with disturbed peripheral blood flow. This composition has no side effects. Specifically, the peripheral blood flow-improving composition contains, as an active ingredient, a extract of a plant of the genus Lepidium of the family Cruciferae. More specifically, the composition contains as an active ingredient a extract of maca plant (Lepidium meyenii Walp). Food and beverage products, perfumes and cosmetics, and pharmaceutical products containing the peripheral blood flow-improving composition are also provided.

The present invention provides systems and methods for treating wounds in patients who lack the innate ability to regulate glucose (e.g., diabetic patients). In one aspect of the invention, a method includes positioning an internal bypass device within the duodenum to inhibit contact between chyme passing therethrough and an internal wall of the duodenum and maintaining the internal bypass device within the duodenum for a sufficient period of time to decrease insulin resistance and reduce a blood glucose level in the patient. The internal bypass device increases peripheral blood flow and elevates an immune system response to accelerate healing of the wound.

The invention relates to the technical field of medical treatment, and particularly discloses a blood in-vitro circulation auxiliary device which comprises a sleeve, a rotor and a driving device, wherein the rotor is arranged in the sleeve, and the driving device is arranged outside the sleeve and used for driving the rotor to rotate. The rotor comprises a rotor cylinder and rotor blades, the rotor cylinder and the sleeve are coaxially arranged, the rotor blades are fixed onto the inner wall of the rotor cylinder, a hollow blood runner is formed in the middle of the rotor, a circular truncatedcone flow guide cylinder is coaxially arranged in the sleeve and positioned on the front side of the rotor, two ends of the flow guide cylinder are closed, the major diameter end of the flow guide cylinder approaches to the rotor, a flow guide channel is formed between the side wall of the flow guide cylinder and the inner wall of the sleeve, and middle blood flow is drained to peripheral blood flow by the flow guide channel. According to the device, later physiological layer flow can be formed.

An electromedical implant (100, 101, 102, 103) for monitoring a cardiac blood flow (B1) of a patient includes a detector (10, 10′, 10″) which obtains a first measurement signal (S1) associated with the cardiac blood flow (B1) and a second measurement signal (S2) associated with the epithoracic, peripheral blood flow (B2). A monitoring assembly (20) then generates a first parameter (P1) from the first measurement signal (S1) which is indicative of a time (tsys) at which blood is ejected from the heart, and a second parameter (2) from the second measurement signal (S2) which is indicative of a time (tgef) of a blood pulse in the thoracic tissue which is associated with the ejection of blood. An evaluation unit (30) then generates a pulse transit time (Δt=tgef−tsys) from the first parameter (P1) and the second parameter (P2). The detector (10, 10′, 10″) includes an impedance measuring unit (12) having an electrode assembly (11, 11′) for detection of at least the second measurement signal (S2) in the form of an impedance signal.

Noninvasive methods and apparatus for detecting blood volume imbalances in a mammalian subject are disclosed. The method includes obtaining baseline measurements of at least three physiological parameters from a subject wherein the parameters are selected from the group consisting of heart rate, electrical body impedance, skin temperature, perfusion index, peripheral blood flow and skin humidity. Measurements of electrical body impedance, skin temperature, perfusion index, peripheral blood flow and skin humidity are taken at one or more extremities of the subject such as the calf, ankle, forearm, thigh, fingers and toes. The physiological parameters for which baseline measurements were obtained are then monitored to detect changes from the baseline measurements that indicate blood volume imbalances. A preferred embodiment comprises computing a baseline blood volume index from the baseline value measurements of each parameter to be monitored and then carrying out the step of monitoring by obtaining real time (current) value measurements of these parameters which are inputted into an algorithm which computes a real time (current) blood volume index based upon the differences between the baseline and real time (current) value measurements.

The present invention provides systems and methods for treating wounds in patients who lack the innate ability to regulate glucose (e.g., diabetic patients). In one aspect of the invention, a method includes positioning an internal bypass device within the duodenum to inhibit contact between chyme passing therethrough and an internal wall of the duodenum and maintaining the internal bypass device within the duodenum for a sufficient period of time to decrease insulin resistance and reduce a blood glucose level in the patient. The internal bypass device increases peripheral blood flow and elevates an immune system response to accelerate healing of the wound.

Provided is a cell preparation for treating a peripheral blood flow disorder, the cell preparation including pluripotent stem cells (Muse cells) which are SSEA-3 positive and derived from mesenchymal tissues of a living body or cultured mesenchymal cells. The peripheral blood flow disorder is preferably a peripheral arterial disease, and more preferably, chronic arterial obstruction of the limbs.

In a system and method for peripheral impedance plethysmography, an electrode for application to the patient's limb includes two outer current electrodes and two inner voltage electrodes. A distance between the two inner electrodes is automatically input into an analyzing device, either as a pre-stored value or as determined automatically from the electrode. Peripheral blood flow is calculated in accordance with that distance.

This application relates to the field of biomedical engineering, and discloses a method and system for evaluating the individualized blood perfusion rate of biological tissues. Based on the influence of peripheral blood flow on the thawing process of the target biological tissue after freezing, the calculation of local tissue is established by the principle of boundary convection heat transfer. An algorithm for personalized blood perfusion rate, the method includes: obtaining the surface area of ​​the ice ball formed by freezing the target biological tissue; obtaining the temperature gradient of the ice ball surface and its change over time according to the temperature of the ice ball surface The gradient and its variation with time and the surface area of ​​the ice ball determine the personalized blood perfusion rate around the target biological tissue; output the personalized blood perfusion rate around the target biological tissue.

An instrument for synchronously obtaining and analyzing the electronystagmograph associated with dizziness and the ear-peripheral blood flow signal is composed of light-shielding eye mask, micro light source, CCD sensor, raster, infrared light source, infrared detector, signal acquisition card, computer, display and printer.

The invention relates to the field of biomedical engineering, and discloses a biological tissue personalized blood perfusion rate evaluation method and system. The biological tissue personalized blood perfusion rate evaluation method comprises the steps that an algorithm for calculating the local tissue personalized blood perfusion rate is calculated through a boundary convective heat transfer principle based on the influence of peripheral blood flow on the thawing process of a target biological tissue after freezing; the surface area of an ice ball formed by freezing a target biological tissue is obtained; the temperature gradient of the surface of the ice ball and the change of the ice ball along with time are obtained, and the personalized blood perfusion rate around the target biological tissue is determined according to the temperature gradient of the surface of the ice ball, the change of the ice ball along with time and the surface area of the ice ball; and the personalized blood perfusion rate around the target biological tissue is output.

A cell product may be used for treating a peripheral blood flow disorder, and the cell product may include an SSEA-3-positive pluripotent stem cells (Muse cells) derived from a mesenchymal tissue in a living body or a cultured mesenchymal cell. The peripheral blood flow disorder is preferably a peripheral arterial disease, more preferably chronic arterial obstruction in a limb.

A non-invasive detection system with a peripheral vascular blood flow adjusting function comprises a data collecting module, a filtering module, a feature point / section identification module, a data analysis module and a blood flow adjusting function evaluation module. Cuff downstream front arm or hand skin blood flow volume signals are continuously measured before and after blood flow of the brachial artery is blocked by means of the method that the unilateral upper arm is pressurized through a cuff, after the blood flow volume signals are subjected to filtering treatment, a stable blood flow section before compression of the cuff and a congestion section after relieving of cuff compression are identified, and the specific value of average blood flow volumes of the congestion section and the stable blood flow section is calculated to obtain the index of quantitative evaluation for the peripheral vascular blood flow adjusting function. The non-invasive effect is achieved in the whole operating process, the measuring time is short, through feature analysis for a time registration curve of the blood flow, a blood flow changing section dominated by peripheral vascular ischemic reaction is identified, the influence of the upstream artery endothelial function on peripheral blood flow signals can be effectively excluded to achieve targeted evaluation on the human body peripheral vascular blood flow adjusting function, and the pretty good application prospects are achieved.