Biological tissue personalized blood perfusion rate evaluation method and system

A technology of biological tissue and target biological tissue, applied in the fields of blood flow measurement, medical science, sensors, etc., can solve the problem of not considering personalized blood flow conditions, and achieve the effect of precise control of boundary temperature

Active Publication Date: 2021-12-10
MAGI CO LTD
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Problems solved by technology

The existing multimodal ablation surgery planning model does not consider the

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  • Biological tissue personalized blood perfusion rate evaluation method and system
  • Biological tissue personalized blood perfusion rate evaluation method and system
  • Biological tissue personalized blood perfusion rate evaluation method and system

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Embodiment Construction

[0046] In the following description, many technical details are proposed in order to enable readers to better understand the application. However, those skilled in the art can understand that the technical solutions claimed in this application can be realized even without these technical details and various changes and modifications based on the following implementation modes.

[0047] Explanation of some concepts:

[0048] The blood flow condition refers to the richness of blood vessels at the ablation site, the blood flow velocity, etc. The blood flow condition may include: blood perfusion rate, blood convection coefficient, and so on.

[0049] Multi-modal ablation, including cryoablation stage and subsequent heating ablation stage, where cryoablation methods include but not limited to liquid nitrogen ablation, argon-helium ablation and low-temperature alcohol ablation, heating ablation methods include but not limited to radiofrequency ablation, microwave ablation Ablation ...

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Abstract

The invention relates to the field of biomedical engineering, and discloses a biological tissue personalized blood perfusion rate evaluation method and system. The biological tissue personalized blood perfusion rate evaluation method comprises the steps that an algorithm for calculating the local tissue personalized blood perfusion rate is calculated through a boundary convective heat transfer principle based on the influence of peripheral blood flow on the thawing process of a target biological tissue after freezing; the surface area of an ice ball formed by freezing a target biological tissue is obtained; the temperature gradient of the surface of the ice ball and the change of the ice ball along with time are obtained, and the personalized blood perfusion rate around the target biological tissue is determined according to the temperature gradient of the surface of the ice ball, the change of the ice ball along with time and the surface area of the ice ball; and the personalized blood perfusion rate around the target biological tissue is output.

Description

technical field [0001] This application relates to the field of biomedical engineering, in particular to the field of data processing technology combining medical technology and computer technology. Background technique [0002] In recent years, physical ablation of target biological tissues such as tumors, as a minimally invasive ablation method, has been widely used in the treatment of benign and malignant tumors such as liver, lung, and kidney. Common physical ablation methods include cryoablation and thermal ablation. [0003] Specifically, multimodal ablation therapy combines cryoablation and heating ablation, and uses the huge thermal stress generated by rapid temperature changes inside the tumor to completely destroy tumor cells, release tumor antigens, and activate the body's specific immune response to tumors. in various solid tumors. Based on a variety of animal models of highly metastatic tumors and a large number of experimental results, its effect has been pro...

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Application Information

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IPC IPC(8): A61B5/026A61B5/01
CPCA61B5/026A61B5/015
Inventor 王逸飞张康伟张爱丽徐学敏孙建奇
Owner MAGI CO LTD
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