123results about How to "No side effect" patented technology

A preventive or therapeutic agent for asthma, comprising HGF or its salt as an active ingredient.

A novel method for evaluating an effect of an antimicrobial agent which comprises removing the antimicrobial agent remaining in a biological sample or the like to thereby accurately evaluate the effect of the antimicrobial agent without being affected by the remaining antimicrobial agent. A therapeutic agent for onychomycosis which can be obtained according to the evaluation method of the drug effect.

The present invention relates to a synergistic herbal formulation comprising an active fraction from Azadirachta indica designated as Fraction A and a fraction from Citrullus colocynthis designated as Fraction B, along with a fraction C containing an antioxidant from Cucumis sativus extract; and pharmaceutically accepted a carrier wherein the ratio of the components ranging between about 2 to 5.5% of fraction A; about 0.5 to 2.5% of fraction B; about 0.1–0.4% of extract of Cucumis sativus; and about 82–97% of carrier or additive.

The pharmaceutical composition comprising the compound of the invention having 8-azaprostaglandin skeleton represented by formula (I) (wherein, all the symbols have the same meanings as that of the specification.) a salt thereof, a solvate thereof or a cyclodextrin clathrate thereof, or a prodrug thereof and them as active ingredient have EP4 agonistic action and thus are considered useful for the prevention and / or treatment of immunological diseases, asthma, neuronal cell death, arthritis, lung failure, pulmonary fibrosis, pulmonary emphysema, bronchitis, chronic obstructive pulmonary disease, liver damage, acute hepatitis, nephritis, renal insufficiency, hypertension, myocardial ischemia, systemic inflammatory response syndrome, sepsis, hemophagous syndrome, macrophage activation syndrome, Still's disease, Kawasaki disease, burn, systemic granulomatosis, ulcerative colitis, Crohn's disease, hypercytokinemia at dialysis, multiple organ failure, shock and glaucoma, etc. Furthermore, the compounds also have an action of accelerating bone formation, so it is expected to be useful for the prevention and / or treatment of diseases associated with loss in bone mass, for example, primary osteoporosis, secondary osteoporosis, bone metastasis of cancer, hypercalcemia, Paget's disease, bone loss, osteonecrosis, bone formation after bone operation, alternative treatment for bone grafting.

A device for preventing and treating myopia includes a base, a spectacles frame (1), a holder (3) and a lens (2). The holder (3) is mounted on the base; a visual target (4) is placed on the base. The spectacles frame (1) is connected to the holder (3) by adjustable connecting parts (31,32,33,34,35), so the distance between the spectacles frame (1) and the visual target (4) which is placed on the base is adjustable.

It is to provide a pharmaceutical composition which is different from an existing therapeutic agent of an adult disease, of a biochemical reaction-inhibiting type, and which action mechanism is to improve the basal metabolism, wherein the composition has no side effects, and does not generate drug resistance against adult disease; and a method for preventing / treating an adult disease by using the same. It is to provide a composition for preventing / ameliorating an adult disease such as metabolic syndrome, diabetes, hyperlipidemia, hypertension, impaired liver function, renal failure, adiposity, erectile dysfunction, menopausal disorder, shoulder discomfort, and low back pain, comprising 5-aminolevulinic acid (ALA), its derivative, or salt thereof, preferably comprising ALA, its derivative, or salt thereof, and an iron compound such as sodium ferrous citrate, iron sodium citrate and iron ammonium citrate; a food or food material for preventing / ameliorating an adult disease comprising the composition; and a method for using the composition for preparing an agent for preventing / ameliorating an adult disease.

The present invention discloses a method for remolding bone marrow microenvironment in a subject having an impaired bone marrow microenvironment, which comprises implanting a composition comprising isolated mesenchymal stromal cells (MSCs) into the bone marrow cavity of the subject. The method of the present invention successfully remolds the bone marrow microenvironment, recovers the normal hematopoiesis of bone marrow, inhibits / delays the pathological process of leukemia and significantly prolongs the survival period. In addition, the method according to the present invention can be used for the treatment of hematologic tumors such as leukemia and aplastic anemia (AA), which is safe and effective but has no side effects.

A device for preventing and treating myopia includes a base, a spectacles frame (1), a holder (3) and a lens (2). The holder (3) is mounted on the base; a visual target (4) is placed on the base. The spectacles frame (1) is connected to the holder (3) by adjustable connecting parts (31,32,33,34,35), so the distance between the spectacles frame (1) and the visual target (4) which is placed on the base is adjustable.

A method of preparing a Chinese medicine for treatment of diabetes, the medicine including the Radix Rehmanniae Preparata, prepared Asiatic Comelian Cherry fruit, tree peony bark, Common Yam Rhizome, Indian bread, Oriental Waterplain rhizome, and refined edible vegetable oil. The tree peony bark is distilled and its residue, the Radix Rehmanniae Preparata, the Common Yam Rhizome and the Indian bread are decocted, then paeonol mother liquor is added to obtain extractum I by centrifugation and concentration. The prepared Asiatic Comelian Cherry fruit and the Oriental Waterplain rhizome are extracted in the refluxing alcohol and concentrated to obtain extractum II. The two extractum are mixed and concentrated to the thick paste; the thick paste is dried, crushed and sifted. The refined paeonol is crushed and added to the extractum powder. The mixed powder is combined with vegetable oil, milled and sifted. The fine powder is made into soft capsule.

This invention provides albumin preparations with safety and without any risk of side effects, which are free from viruses or contaminating proteins and can be stably stored over a long time while showing neither changes in appearance nor decrease in content.There are provided a stabilized albumin preparation produced by uniformly mixing a medium-chain fatty acid or a salt thereof and a sulfur-containing amino acid or a derivative thereof with an aqueous albumin solution (e.g., a buffer such as phosphate buffer which can be administered as pharmaceutical preparations, injection water, or a physiological saline) and dissolving them therein, and then processing the mixture solution into a formulation suitable for parenteral administration such as an intravenous fluid preparation or an injectable solution, and a stabilization method for an albumin preparation.